Homo sapiens

Central nervous system macrophage Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Dentate gyrus granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Hippocampal ca4 neuron

Hippocampal field

50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Oligodendrocyte precursor cell

Neocortex

Adult stage

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Endothelial cell of artery

Mesenteric artery

42-year-old stage 28-year-old stage 59-year-old stage 46-year-old stage

Normal Type 2 diabetes mellitus

Female Male

10x 3' v3

Cell

Homo sapiens

T cell Glutamatergic neuron Oligodendrocyte precursor cell Oligodendrocyte Macrophage Microglial cell Gabaergic interneuron Mural cell Pvalb gabaergic interneuron Astrocyte

Dorsolateral prefrontal cortex

61-year-old stage 54-year-old stage 51-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Paneth cell Enteroendocrine cell Goblet cell Enterocyte Transit amplifying cell Neuron Mesenchymal stem cell Myofibroblast cell

Intestinal mucosa

26-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Obsolete inhibitory neuron Oligodendrocyte Astrocyte of the cerebellum Brain microvascular endothelial cell Obsolete excitatory neuron

Normal

10x 3' v2

Microcebus murinus

T cell Neutrophil Natural killer cell Erythroid progenitor cell Endothelial cell Mature nk t cell Hematopoietic precursor cell Cd8-positive, alpha-beta t cell Platelet Erythroid lineage cell Plasmacytoid dendritic cell Lymphocyte Macrophage Myeloid cell Plasma cell Cd4-positive, alpha-beta t cell Eosinophil Mesothelial cell B cell Granulocyte monocyte progenitor cell Monocyte Basophil Conventional dendritic cell Dendritic cell

Spleen

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Kupffer cell Classical monocyte Liver dendritic cell Macrophage Myeloid cell Monocyte

Caudate lobe of liver

Late adult stage Prime adult stage Young adult stage

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

Paneth cell Enteroendocrine cell Goblet cell Enterocyte Transit amplifying cell Neuron Mesenchymal stem cell Myofibroblast cell

Intestinal mucosa

26-year-old stage 29-year-old stage

Normal

Female Male

10x 3' v3

Cell

Danio rerio

Rohon-beard neuron Neuron

Trigeminal ganglion Epibranchial ganglion Spinal cord Vestibulocochlear ganglion Cranial ganglion Lateral line ganglion

Pharyngula:prim-15 Hatching:long-pec Larval:protruding-mouth Pharyngula:prim-25 Segmentation:26+ somites Segmentation:14-19 somites Hatching:pec-fin Segmentation:20-25 somites Pharyngula:high-pec Pharyngula:prim-5

Normal

Sci-rna-seq3

Nucleus

Homo sapiens

Macrophage Malignant cell Monocyte Fibroblast

Liver

54-year-old stage

Breast cancer

Female

10x 3' v2

Cell

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2