Homo sapiens

Platelet

Blood

75-year-old stage Sixth decade stage 53-year-old stage 61-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 39-year-old stage 29-year-old stage 38-year-old stage Fifth decade stage 84-year-old stage 82-year-old stage Third decade stage 80 year-old and over stage 49-year-old stage Seventh decade stage 59-year-old stage Adult stage 67-year-old stage 62-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 36-year-old stage Fourth decade stage 63-year-old stage Eighth decade stage 47-year-old stage 73-year-old stage 27-year-old stage

Covid-19 Normal

Female Male

Seq-well 10x 3' v3 10x 3' v2

Cell

Mus musculus

T cell Neural stem cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Mature nk t cell Cd8-positive, alpha-beta t cell Brain pericyte Ependymal cell Macrophage Microglial cell Interneuron Bergmann glial cell Neuron Neuroepithelial stem cell Astrocyte Medium spiny neuron

Brain

3-month-old stage 20-month-old stage and over 18-month-old stage

Normal

Female Male

Smart-seq2

Cell

Microcebus murinus

Neutrophil Bladder urothelial cell Endothelial cell of lymphatic vessel Non-myelinating schwann cell Endothelial cell of artery Capillary endothelial cell Smooth muscle cell Plasmacytoid dendritic cell Lymphocyte Adipocyte Macrophage Innate lymphoid cell Plasma cell Cd4-positive, alpha-beta t cell Vein endothelial cell Mesothelial cell B cell Pericyte Monocyte Vascular associated smooth muscle cell Myofibroblast cell Basophil Conventional dendritic cell Fibroblast Myelinating schwann cell Dendritic cell

Urinary bladder

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Mus musculus

Ependymal cell Obsolete excitatory neuron

Normal

10x 3' v2

Mus musculus

Microglial cell Neural crest derived fibroblast Deuterosomal cell Neuroblast (sensu vertebrata) Radial glial cell Neuron associated cell

Multiciliated ependymal cell

Theiler stage 27

Normal

10x 3' v3

Cell

Homo sapiens

Corticothalamic-projecting glutamatergic cortical neuron

Neocortex

Adult stage

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Perivascular cell Smooth muscle cell Pericyte

Forebrain meninges Brain meninx Meninx

13th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage Carnegie stage 21 Carnegie stage 16 Carnegie stage 18

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Neutrophil Mature nk t cell Platelet Myeloid cell Plasma cell B cell Dendritic cell

Blood

66-year-old stage

Covid-19

Female

10x 3' v3

Cell

Homo sapiens

Glutamatergic neuron Serotonergic neuron Dopaminergic neuron Neuroblast (sensu vertebrata) Glycinergic neuron Neuron Sensory neuron of dorsal root ganglion Gabaergic neuron

Medulla oblongata Hindbrain Telencephalon Midbrain Cerebellum Brain Diencephalon Pons

13th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage 10th week post-fertilization stage Embryonic stage

Normal

Female Male

10x multiome

Nucleus