Mus musculus

Oligodendrocyte precursor cell Oligodendrocyte Brain microvascular endothelial cell Obsolete excitatory neuron Astrocyte

Normal

10x 3' v2

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Memory b cell Naive b cell

Breast

43-year-old stage 85-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 55-year-old stage 82-year-old stage 50-year-old stage 57-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 67-year-old stage 41-year-old stage 60-year-old stage 63-year-old stage 47-year-old stage 73-year-old stage

Invasive ductal breast carcinoma Invasive lobular breast carcinoma Breast carcinoma

Female

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Macaca mulatta

Serotonergic neuron

Dorsolateral prefrontal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Ventral lateral nucleus of thalamus Inferior temporal gyrus Medulla oblongata Prefrontal cortex Midbrain Entorhinal cortex Nucleus accumbens Cerebrocerebellum Primary somatosensory cortex Primary auditory cortex Primary motor cortex Inferior parietal cortex Head of caudate nucleus Corpus callosum Hippocampal formation Perirhinal cortex Pons Cerebellar vermis Anterior cingulate cortex Superior temporal sulcus Superior parietal cortex Lateral geniculate body Amygdala

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Mus musculus

T cell Granulocyte Multiciliated columnar cell of tracheobronchial tree Endothelial cell Macrophage Keratinocyte Smooth muscle cell of trachea Mucus secreting cell Fibroblast Basal epithelial cell of tracheobronchial tree Chondrocyte

Trachea

3-month-old stage 20-month-old stage and over 18-month-old stage

Normal

Female Male

Smart-seq2

Cell

Mus musculus

Oligodendrocyte Brain microvascular endothelial cell Obsolete excitatory neuron

Normal

10x 3' v2

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Neutrophil Stromal cell Mast cell Cd8-positive, alpha-beta t cell Melanocyte Intermediate monocyte Vestibular dark cell Endothelial cell of vascular tree Macrophage Cd4-positive, alpha-beta t cell Supporting cell of vestibular epithelium B cell Pericyte Monocyte Vascular associated smooth muscle cell Hematopoietic cell

Crista ampullaris Utricle of membranous labyrinth

45-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Endothelial cell of artery Smooth muscle cell Vein endothelial cell Fibroblast

Ureter

69-year-old stage 75-year-old stage 65-year-old stage 85-year-old stage 68-year-old stage 82-year-old stage 81-year-old stage 74-year-old stage 79-year-old stage

Normal

Female Male

10x 3' v3

Cell

Mus musculus

T cell Natural killer cell Endothelial cell Cd8-positive, alpha-beta t cell Epithelial cell Macrophage Myeloid cell Cd4-positive, alpha-beta t cell Mesenchymal stem cell of adipose tissue B cell

Mesenteric fat pad

3-month-old stage 20-month-old stage and over 18-month-old stage

Normal

Female Male

Smart-seq2

Cell