Mus musculus

Mature nk t cell Macrophage Microglial cell Mature microglial cell

Spinal cord

3-6 month-old mature stage

Spinal cord injury Normal

Female

10x 3' v2

Nucleus

Homo sapiens

Blood vessel smooth muscle cell Smooth muscle cell Smooth muscle cell of the pulmonary artery Lung pericyte

Bronchus Lung Trachea Upper lobe of left lung Lower lobe of left lung

66-year-old stage 75-year-old stage Sixth decade stage 29-year-old stage 35-year-old stage Seventh decade stage 58-year-old stage 59-year-old stage 64-year-old stage

Normal

Female Male

10x 5' transcription profiling 10x 3' v3 10x 3' v2

Cell Nucleus

Mus musculus

Obsolete inhibitory neuron Oligodendrocyte precursor cell Oligodendrocyte Obsolete excitatory neuron Neuron Astrocyte

Normal

10x 3' v2

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Erythrocyte Mature nk t cell Myeloid cell Plasma cell B cell Dendritic cell

Blood

74-year-old stage

Covid-19

Female

10x 3' v3

Cell

Mus musculus

Alpha motor neuron Gamma motor neuron Motor neuron

Cervical spinal cord Thoracic spinal cord Lumbar spinal cord

8-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Microcebus murinus

T cell Neutrophil Natural killer cell Endothelial cell of lymphatic vessel Endothelial cell Erythroid lineage cell Nodal myocyte Myeloid cell Plasma cell Mesothelial cell of epicardium Mesothelial cell Cardiac muscle cell Pericyte Neuron Regular atrial cardiac myocyte Vascular associated smooth muscle cell Regular ventricular cardiac myocyte Fibroblast Pulmonary alveolar type 2 cell Purkinje myocyte

Heart right ventricle Right cardiac atrium Cardiac muscle tissue Heart Heart left ventricle Left cardiac atrium

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Endocardial cell Dendritic cell, human Endothelial cell of lymphatic vessel Cd8-positive, alpha-beta t cell Endothelial cell of artery Smooth muscle cell Smooth muscle cell of the pulmonary artery Adipocyte Cd8-positive, alpha-beta cytotoxic t cell Macrophage Cd16-positive, cd56-dim natural killer cell, human Glial cell Plasma cell Vein endothelial cell Mesothelial cell Pericyte Mucosal invariant t cell Regular ventricular cardiac myocyte Fibroblast of cardiac tissue

Heart right ventricle

Sixth decade stage Seventh decade stage

Normal

Female Male

Visium spatial gene expression v1

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Neurectodermal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Endothelial cell Iga plasma cell Ionocyte Cd8-positive, alpha-beta cytotoxic t cell Duct epithelial cell Acinar cell of salivary gland Cd4-positive, alpha-beta t cell B cell Fibroblast Dendritic cell

Labial gland

61-year-old stage

Sjogren syndrome

Female

Visium spatial gene expression v1

Mus musculus

Endothelial cell of hepatic sinusoid Neutrophil Hepatocyte Endothelial cell of periportal hepatic sinusoid Erythrocyte Kupffer cell Intermediate monocyte Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Endothelial cell of pericentral hepatic sinusoid Cholangiocyte Mesothelial cell B cell Peritoneal macrophage Basophil Conventional dendritic cell Fibroblast

Liver

10-month-old stage

Metabolic dysfunction-associated steatotic liver disease

Male

Visium spatial gene expression v1

Mus musculus

Neutrophil Germinal center b cell Enteric neuron Stem cell Epithelial cell Group 3 innate lymphoid cell Goblet cell Memory b cell Enterocyte Transit amplifying cell Myofibroblast cell Fibroblast

Colon

Prime adult stage

Normal

Visium spatial gene expression v1