Drosophila melanogaster

Neuron Nociceptive neuron Fat cell Tracheolar cell Glial cell Somatic precursor cell Male germline cell Gustatory receptor neuron Hemocyte Epithelial cell Muscle cell Pheromone-sensing neuron Mechanosensory neuron Sensory neuron Oenocyte Neuron Female germline cell

Wing

Day 5 of adulthood

Normal

Female Male

10x 3' v3

Homo sapiens

Cd1c-positive myeloid dendritic cell Natural killer cell Cd4-negative, cd8-negative, alpha-beta intraepithelial t cell Gamma-delta t cell Activated cd4-positive, alpha-beta t cell Hematopoietic precursor cell Platelet Cd141-positive myeloid dendritic cell Effector memory cd4-positive, alpha-beta t cell Erythroid lineage cell Plasmacytoid dendritic cell Cd8-positive, alpha-beta memory t cell Cd4-positive, alpha-beta cytotoxic t cell Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Cd16-positive, cd56-dim natural killer cell, human Innate lymphoid cell Regulatory t cell Mature b cell Activated cd8-positive, alpha-beta t cell Plasmablast Cd14-positive monocyte Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Monocyte Naive b cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell

Blood

Fifth decade stage Adult stage Prime adult stage Young adult stage

Leishmaniasis Visceral leishmaniasis Normal Hiv infectious disease

Male

10x 5' v1

Cell

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Callithrix jacchus

Neuron

Central amygdaloid nucleus Basal forebrain

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Callithrix jacchus

Gabaergic neuron

Lateral amygdaloid nucleus Medial amygdaloid nucleus Amygdala

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell Anterior visceral endoderm cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Gamma-delta t cell Activated cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell Activated cd8-positive, alpha-beta t cell Myeloid cell Cd4-positive, alpha-beta memory t cell B cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Naive b cell Cd16-negative, cd56-bright natural killer cell, human

Blood

26-year-old stage

Normal Common variable immunodeficiency

Male

10x 5' v1

Cell

Homo sapiens

Lymphocyte

Heart right ventricle Apex of heart Heart left ventricle Interventricular septum

Pediatric stage Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Postnatal stage Fourth decade stage Eighth decade stage

Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Normal Non-compaction cardiomyopathy

Female Male

10x 3' v3 10x 3' v2

Nucleus

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2

Mus musculus

Cardiac valve cell Spinal cord interneuron Premigratory neural crest cell Paraxial cell Notochordal cell Neuroplacodal cell Hemangioblast Mesodermal cell Gut endothelial cell Primitive red blood cell Splanchnic mesodermal cell Surface ectodermal cell Midbrain dopaminergic neuron Endodermal cell

Embryo

Theiler stage 14

Normal

Slide-seqv2

Homo sapiens

Midbrain-derived inhibitory neuron T cell Central nervous system macrophage Oligodendrocyte precursor cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Cerebellar granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell Neuron Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron Mammillary body neuron

Hypothalamus

42-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus