Mus musculus

Neuron

Normal

Mixed sex

10x 3' v3

Homo sapiens

T cell Erythrocyte Neural cell Microglial cell B cell Monocyte

Dorsolateral prefrontal cortex Temporal cortex

Adult stage

Temporal lobe epilepsy Alzheimer disease

Female Male

10x 3' v2

Cell

Homo sapiens

Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Kidney proximal convoluted tubule epithelial cell

Renal medulla

72-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

L6b glutamatergic cortical neuron

Middle temporal gyrus

69-year-old stage 75-year-old stage 65-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage Adult stage 77-year-old stage 86-year-old stage 70-year-old stage 60-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Endothelial cell of venule Endothelial cell of artery Capillary endothelial cell Endothelial cell of uterus

Endometrium Myometrium

37-year-old stage 26-year-old stage 29-year-old stage 28-year-old stage 23-year-old stage 32-year-old stage 31-year-old stage Young adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Mus musculus

Visceromotor neuron Cholinergic neuron Motor neuron

Cervical spinal cord Thoracic spinal cord Lumbar spinal cord

8-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Cell Early spermatid Sertoli cell Late spermatid Male germ line stem cell Obsolete somatic cell Spermatocyte Spermatogonium

Testis

28-year-old stage 32-year-old stage

Normal

Male

10x genomics v2

Microcebus murinus

Osteoblast Neutrophil Stromal cell Endothelial cell of lymphatic vessel Erythroid progenitor cell Non-myelinating schwann cell Endothelial cell Mature nk t cell Endothelial cell of sinusoid Hematopoietic precursor cell Cd8-positive, alpha-beta t cell Preosteoblast Tendon cell Erythroid lineage cell Capillary endothelial cell Plasmacytoid dendritic cell Megakaryocyte progenitor cell Lymphocyte Adipocyte Macrophage Myeloid cell Plasma cell Cd4-positive, alpha-beta t cell B cell Granulocyte monocyte progenitor cell Monocyte Vascular associated smooth muscle cell Basophil Conventional dendritic cell Fibroblast Myelinating schwann cell Dendritic cell Chondrocyte

Limb bone Vertebral column Bone element

Post-juvenile adult stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Drosophila melanogaster

Neuron Nociceptive neuron Fat cell Tracheolar cell Glial cell Somatic precursor cell Male germline cell Gustatory receptor neuron Hemocyte Epithelial cell Muscle cell Pheromone-sensing neuron Mechanosensory neuron Sensory neuron Oenocyte Neuron Female germline cell

Wing

Day 5 of adulthood

Normal

Female Male

10x 3' v3

Homo sapiens

Glutamatergic neuron

Superior frontal gyrus

87-year-old stage 71-year-old stage 82-year-old stage 50-year-old stage 72-year-old stage 80 year-old and over stage 77-year-old stage 60-year-old stage

Normal Alzheimer disease

Male

10x 3' v2

Nucleus

Homo sapiens

Ciliated cell Secretory cell Basal cell

Lung Epithelial cell of lung

Middle aged stage Late adult stage

Normal

10x 3' v3

Cell