Homo sapiens

T cell Neutrophil Natural killer cell Endothelial cell Mature nk t cell Mast cell Cd8-positive, alpha-beta t cell Pancreatic acinar cell Pancreatic pp cell Classical monocyte Intermediate monocyte Pancreatic a cell Macrophage Pancreatic d cell Pancreatic stellate cell Plasma cell Cd4-positive, alpha-beta t cell Type b pancreatic cell B cell Monocyte Pancreatic ductal cell Fibroblast Non-classical monocyte

Exocrine pancreas Endocrine pancreas

37-year-old stage 56-year-old stage 59-year-old stage

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Midbrain-derived inhibitory neuron T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Cerebellar granule cell Lamp5 lhx6 neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Cerebellar inhibitory gabaergic interneuron Ependymal cell Microglial cell Thalamic excitatory neuron B cell Pericyte Cerebral cortex neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Astrocyte Fibroblast Medium spiny neuron

Gray matter of midbrain

29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Neutrophil Classical monocyte Plasmacytoid dendritic cell Conventional dendritic cell

Pleural effusion Lung Axilla Liver Bone spine Brain Adrenal gland Lymph node

69-year-old stage 75-year-old stage 65-year-old stage 71-year-old stage 85-year-old stage 68-year-old stage 44-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 80-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 70-year-old stage 78-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage

Lung adenocarcinoma Normal Small cell lung carcinoma

Female Male

10x 3' transcription profiling 10x 3' v3 10x 3' v2

Cell

Mus musculus

Trigeminal neuron

Trigeminal ganglion

8-week-old stage

Peripheral neuropathy Normal

Female Male

Bd rhapsody whole transcriptome analysis Indrop Smart-seq3 10x 3' v3 Drop-seq

Cell Nucleus

Homo sapiens

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Cortex of kidney

65-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Adipocyte of omentum tissue

Visceral fat

34-year-old stage 53-year-old stage 48-year-old stage 29-year-old stage 28-year-old stage 24-year-old stage Adult stage 33-year-old stage 41-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Dorsolateral prefrontal cortex

69-year-old stage 75-year-old stage 42-year-old stage 89-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage 77-year-old stage 86-year-old stage 70-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Mus musculus

Tracheal epithelial cell

Tracheal epithelial cell

Mature stage

Normal

10x 3' v3

Cell

Homo sapiens

Secondary lens fiber Lens epithelial cell Lens fiber cell Anterior lens cell

Lens of camera-type eye

Adult stage 33-year-old stage

Normal

Male

10x 3' v3

Nucleus

Mus musculus

Obsolete inhibitory neuron Oligodendrocyte precursor cell Oligodendrocyte Microglial cell Brain microvascular endothelial cell Astrocyte

Normal

10x 3' v2

Homo sapiens

Intestinal crypt stem cell of colon Secretory cell Tuft cell of colon Best4+ colonocyte Malignant cell Colon goblet cell Early colonocyte Colonocyte Enteroendocrine cell of colon

Caecum Liver Hepatic flexure of colon Sigmoid colon

37-year-old stage 65-year-old stage 68-year-old stage 39-year-old stage 50-year-old stage 74-year-old stage 49-year-old stage 64-year-old stage 45-year-old stage

Colorectal cancer Normal

Female Male

10x 3' v3

Cell

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Normal

Male

Slide-seqv2