Drosophila melanogaster

Neuron Adult abdominal pericardial cell Indirect flight muscle cell Fat cell Cardial cell Tracheolar cell Glial cell Somatic precursor cell Male germline cell Crystal cell Hemocyte Epithelial cell Muscle cell Adult tracheocyte Embryonic/larval crystal cell Sensory neuron Oenocyte Adult oenocyte Neuron Adult heart ventral longitudinal muscle cell Female germline cell

Heart

Day 5 of adulthood

Normal

Female Male

10x 3' v3

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

6-month-old stage

Autosomal dominant polycystic kidney disease

Male

Slide-seqv2

Homo sapiens

Podocyte Parietal epithelial cell Endothelial cell Kidney loop of henle thin descending limb epithelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney connecting tubule epithelial cell Kidney loop of henle thick ascending limb epithelial cell Kidney loop of henle epithelial cell Mesangial cell Pericyte Kidney proximal convoluted tubule epithelial cell

Renal medulla

64-year-old stage

Normal

Female

Slide-seqv2

Homo sapiens

Iga plasma cell Igg plasma cell Unswitched memory b cell Naive b cell Class switched memory b cell

Breast

Adult stage Prime adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Hepatocyte Endothelial cell Mature nk t cell Macrophage Plasma cell Malignant cell B cell Monocyte Fibroblast

Liver

40-year-old stage

Breast cancer

Female

10x 3' v3

Cell

Homo sapiens

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Cortex of kidney

64-year-old stage

Normal

Female

Slide-seqv2

Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Dentate gyrus granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell B cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Hippocampal ca4 neuron

Hippocampal field

29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney granular cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Macula densa epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Cortex of kidney

56-year-old stage

Normal

Male

Slide-seqv2

Homo sapiens

Muscle cell Skeletal muscle myoblast Myoblast

Hindlimb Forelimb

Carnegie stage 19 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage Carnegie stage 17 Carnegie stage 16 Carnegie stage 15 Carnegie stage 18

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Pan troglodytes

Cell Early spermatid Sertoli cell Late spermatid Male germ line stem cell Obsolete somatic cell Spermatocyte Spermatogonium

Testis

Late adult stage

Normal

Male

10x genomics v2

Mus musculus

Podocyte Endothelial cell Kidney interstitial fibroblast Blood vessel smooth muscle cell Kidney collecting duct intercalated cell Leukocyte Macrophage Kidney distal convoluted tubule epithelial cell Kidney collecting duct principal cell Kidney loop of henle thick ascending limb epithelial cell Mesangial cell Kidney proximal convoluted tubule epithelial cell

Kidney

13-week-old stage

Diabetic kidney disease

Male

Slide-seqv2