Homo sapiens

Osteoblast Neutrophil Muscle cell Endothelial tip cell Natural killer cell Erythrocyte Endothelial cell Mature nk t cell Pro-b cell Endothelial cell of sinusoid Myeloid lineage restricted progenitor cell Mast cell Cd8-positive, alpha-beta t cell Preosteoblast Schwann cell Plasmacytoid dendritic cell Muscle precursor cell Precursor b cell Lymphoid lineage restricted progenitor cell Early lymphoid progenitor Basophil mast progenitor cell Common dendritic progenitor Adipocyte Primitive red blood cell Macrophage Regulatory t cell Myelocyte Macrophage dendritic cell progenitor Immature innate lymphoid cell Promonocyte Common myeloid progenitor Cd4-positive, alpha-beta t cell Cd14-positive monocyte Hematopoietic multipotent progenitor cell Eosinophil Megakaryocyte Endosteal cell Precursor cell Granulocyte monocyte progenitor cell Progenitor cell Promyelocyte Immature natural killer cell Immature b cell Megakaryocyte-erythroid progenitor cell Fraction a pre-pro b cell Naive b cell Myofibroblast cell Basophil Fibroblast Osteoclast Dendritic cell Cd16-negative, cd56-bright natural killer cell, human Chondrocyte

Bone marrow

19th week post-fertilization stage 13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 17th week post-fertilization stage 16th week post-fertilization stage

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

Mature t cell

Systemic lupus erythematosus Normal Multiple sclerosis Myasthenia gravis

10x 5' v2

Mus musculus

Blood vessel endothelial cell Microvascular endothelial cell Tendon cell Schwann cell Smooth muscle cell Lymphocyte Adipocyte Macrophage Type iib muscle cell Type iix muscle cell Fibro/adipogenic progenitor cell Perineurial cell Pericyte Skeletal muscle satellite stem cell Neuromuscular junction nucleus Myotendinous junction nucleus Type iia muscle cell Intermediate muscle cell

Gastrocnemius Skeletal muscle tissue of tibialis anterior

Prime adult stage

Lesion of sciatic nerve Toxin-mediated infectious botulism Neuromuscular junction disease Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Osteoblast Fibroblast of dermis Hypertrophic chondrocyte Tendon cell Smooth muscle cell Articular chondrocyte Connective tissue cell Chondroblast Mesenchymal cell Pericyte Fibroblast Chondrocyte Muscle fibroblast

Hindlimb Forelimb

Carnegie stage 19 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage Carnegie stage 17 Carnegie stage 16 Carnegie stage 15 Carnegie stage 18

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

Neoplastic cell

Temporal lobe Dorsal plus ventral thalamus Cerebral hemisphere Cerebellum

13-year-old stage 17-year-old stage 8-year-old stage 15-year-old stage 12-year-old stage 9-year-old stage 14-year-old stage 16-year-old stage 23-year-old stage 18-year-old stage 22-year-old stage 19-year-old stage 5-year-old stage 11-year-old stage 6-year-old stage 7-year-old stage 10-year-old stage 4-year-old stage

Pediatric high-grade glioma

Female Male

10x 3' v3

Nucleus

Homo sapiens

Glutamatergic neuron Oligodendrocyte precursor cell Perivascular cell Endothelial cell Oligodendrocyte Vascular leptomeningeal cell Ependymal cell Microglial cell Pericyte Astrocyte Gabaergic neuron

Dorsolateral prefrontal cortex Caudate nucleus Hippocampal formation Anterior cingulate cortex

61-year-old stage 39-year-old stage 14-year-old stage Infant stage 62-year-old stage 20-year-old stage 6-year-old stage 4-year-old stage

Normal

Female Male

10x multiome

Nucleus

Mus musculus

Glutamatergic neuron Oligodendrocyte Vascular leptomeningeal cell Lymphocyte Smooth muscle cell of the brain vasculature Microglial cell Brain microvascular endothelial cell Forebrain neuroblast Choroid plexus epithelial cell Gabaergic neuron Medium spiny neuron

Prion disease Normal

10x 3' transcription profiling

Drosophila melanogaster

Neuron Adult somatic muscle cell of head Outer photoreceptor cell Optic-lobe-associated cortex glial cell Transmedullary y neuron tmy8 T2 neuron T5c neuron Adult lamina marginal glial cell T4c neuron Transmedullary y neuron tmy4 Gamma kenyon cell Transmedullary neuron tm3 Subperineurial glial cell Alpha/beta kenyon cell Transmedullary neuron tm1 Fat cell Proximal medullary amacrine neuron pm2 Alpha'/beta' kenyon cell Photoreceptor cell r7 Lamina wide-field 2 neuron Lobula columnar neuron lc10 Distal medullary amacrine neuron dm10 T3 neuron Glial cell Adult optic chiasma glial cell Centrifugal neuron c2 Lamina monopolar neuron l4 Photoreceptor cell r8 Hemocyte Ocellar retinula cell Proximal medullary amacrine neuron pm4 T4a neuron Antennal lobe projection neuron Johnston organ neuron Tyraminergic neuron Lobula columnar neuron lc12 Epithelial cell Ensheathing glial cell Muscle cell Transmedullary neuron tm2 Transmedullary neuron tm9 T4d neuron Transmedullary neuron tm20 Transmedullary neuron tm5c Lamina monopolar neuron l2 Distal medullary amacrine neuron dm8a Distal medullary amacrine neuron dm9 Lamina wide-field 1 neuron Adult lamina epithelial glial cell Distal medullary amacrine neuron dm12 Medulla intrinsic neuron mi4 Lamina monopolar neuron l3 T5d neuron Auditory sensory neuron Distal medullary amacrine neuron dm11 Columnar neuron t1 Adult olfactory receptor neuron gr21a/63a Transmedullary y neuron tmy14 Kenyon cell Sensory neuron T4b neuron T4 neuron Adult brain perineurial glial cell Centrifugal neuron c3 Olfactory receptor neuron Adult astrocyte-like glial cell T2a neuron Distal medullary amacrine neuron dm3 T5 neuron Medulla intrinsic neuron mi15 Transmedullary y neuron tmy5a Dopaminergic neuron Transmedullary neuron tm29 T5a neuron Adult dopaminergic pam neuron Medulla intrinsic neuron mi1 Medulla intrinsic neuron mi9 Pigment cell Octopaminergic neuron T5b neuron Transmedullary neuron tm4 Adult brain cell body glial cell Lamina monopolar neuron l5 Cone cell Lamina monopolar neuron l1 Lobula columnar neuron lc17

Head

Day 5 of adulthood

Normal

Female Male Mixed sex

10x 3' v3

Homo sapiens

Ciliated cell Supporting cell Stromal cell of ovary Uterine smooth muscle cell Leukocyte Epithelial cell Endothelial cell of uterus Myeloid cell Glandular secretory epithelial cell Fibroblast

Endometrium

37-year-old stage 26-year-old stage 29-year-old stage Third decade stage Young adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Vip gabaergic interneuron

Dorsolateral prefrontal cortex

69-year-old stage 75-year-old stage 42-year-old stage 89-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage 77-year-old stage 86-year-old stage 70-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

T cell Natural killer cell Endothelial cell of lymphatic vessel Endothelial cell Mature nk t cell Mammary gland epithelial cell Cd8-positive, alpha-beta t cell Luminal epithelial cell of mammary gland Macrophage Memory b cell Basal-myoepithelial cell of mammary gland Myeloid cell Plasmablast Fibroblast of breast Cd4-positive, alpha-beta t cell Pericyte Monocyte Naive b cell

Breast

42-year-old stage 43-year-old stage 85-year-old stage 61-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 55-year-old stage 82-year-old stage 50-year-old stage 57-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 67-year-old stage 41-year-old stage 60-year-old stage 63-year-old stage 47-year-old stage 73-year-old stage

Invasive ductal breast carcinoma Invasive lobular breast carcinoma Breast carcinoma

Female

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Retinal ganglion cell Retinal pigment epithelial cell Retinal bipolar neuron Retinal cone cell Retinal rod cell Myeloid cell Retina horizontal cell Amacrine cell Mueller cell Astrocyte

Retina

65-year-old stage 77-year-old stage 70-year-old stage 79-year-old stage

Normal

Female Male

10x 3' v3

Nucleus