Homo sapiens

Iga plasma cell Fibroblast Inflammatory macrophage Ionocyte Igg plasma cell Smooth muscle cell Dendritic cell B cell Myoepithelial cell Cd8-positive, alpha-beta regulatory t cell Duct epithelial cell Effector cd8-positive, alpha-beta t cell Pro-t cell Alternatively activated macrophage Mature nk t cell Cd4-positive, alpha-beta t cell Acinar cell of salivary gland Cd8-positive, alpha-beta cytotoxic t cell Endothelial cell

Labial gland

54-year-old stage 35-year-old stage 39-year-old stage 53-year-old stage 61-year-old stage 48-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 75-year-old stage 50-year-old stage 51-year-old stage 56-year-old stage 43-year-old stage 65-year-old stage 47-year-old stage

Sjogren syndrome Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Fibroblast Memory t cell Astrocyte Effector memory cd8-positive, alpha-beta t cell Smooth muscle cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Exhausted t cell Oligodendrocyte precursor cell Stromal cell Plasma cell B cell Gamma-delta t cell Endothelial cell of high endothelial venule Neoplastic cell Naive thymus-derived cd4-positive, alpha-beta t cell Pericyte Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Effector cd4-positive, alpha-beta t cell Natural killer cell Macrophage Conventional dendritic cell Mature nk t cell Classical monocyte Microglial cell Choroid plexus epithelial cell T cell Mature neutrophil Neuron

Brain

2-month-old stage

Glioblastoma

Female Male

10x 3' v3

Cell

Homo sapiens

Innate lymphoid cell Regular atrial cardiac myocyte Mucosal invariant t cell Cd16-positive, cd56-dim natural killer cell, human Mast cell Dendritic cell, human Cd14-low, cd16-positive monocyte Glial cell Regular ventricular cardiac myocyte Vein endothelial cell Cd14-positive monocyte Endocardial cell Smooth muscle cell Neutrophil Plasma cell B cell Capillary endothelial cell Naive thymus-derived cd4-positive, alpha-beta t cell Pericyte T-helper 2 cell Activated cd4-positive, alpha-beta t cell Atrioventricular bundle cell Smooth muscle cell of the pulmonary artery Cardiac pacemaker cell of sinoatrial node Adipocyte Cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Cd16-negative, cd56-bright natural killer cell, human Macrophage Monocyte Mature nk t cell Mesothelial cell Fibroblast of cardiac tissue Cd8-positive, alpha-beta cytotoxic t cell Endothelial cell Endothelial cell of artery

Heart left ventricle Apex of heart Left cardiac atrium Interventricular septum Right cardiac atrium Sinoatrial node Heart right ventricle Atrioventricular node

Third decade stage Sixth decade stage Eighth decade stage Fifth decade stage Seventh decade stage

Normal

Female Male

Visium spatial gene expression v1

Mus musculus

Retinal rod cell Pituitary gland cell Cochlea auditory hair cell Retinal bipolar neuron Retinal progenitor cell Photoreceptor cell Iris pigment epithelial cell Neural cell Retinal cone cell Epithelial cell of pancreas Pinealocyte

Embryo

Theiler stage 26 Theiler stage 18 Theiler stage 13 Theiler stage 24 Theiler stage 15 Theiler stage 14 Theiler stage 23 Theiler stage 20 Theiler stage 22 Theiler stage 16 Theiler stage 21 Theiler stage 25 Theiler stage 27 Theiler stage 17 Theiler stage 19

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Fibroblast Blood vessel endothelial cell Pericyte Salivary gland glandular cell Endothelial cell of lymphatic vessel Squamous epithelial cell

Mandible Gingiva of lower jaw Tongue Larynx Alveolar ridge of mandible Oral cavity Oropharynx Buccal mucosa Hypopharynx Mouth floor

54-year-old stage 35-year-old stage 62-year-old stage 73-year-old stage 74-year-old stage 72-year-old stage 53-year-old stage 61-year-old stage 57-year-old stage 70-year-old stage 55-year-old stage 58-year-old stage 75-year-old stage 18-year-old stage 51-year-old stage 64-year-old stage 66-year-old stage 77-year-old stage 69-year-old stage 32-year-old stage 80-year-old stage 56-year-old stage 67-year-old stage 65-year-old stage

Head and neck squamous cell carcinoma

Female Male

10x 5' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

L6b glutamatergic cortical neuron Corticothalamic-projecting glutamatergic cortical neuron L5 extratelencephalic projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron

Primary motor cortex Primary visual cortex Dorsolateral prefrontal cortex Primary somatosensory cortex Primary auditory cortex Middle temporal gyrus Anterior cingulate cortex Angular gyrus

Sixth decade stage 42-year-old stage 50-year-old stage 29-year-old stage 60-year-old stage 43-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Common myeloid progenitor Memory b cell Small pre-b-ii cell Plasma cell Dendritic cell Megakaryocyte Erythroid progenitor cell Hematopoietic stem cell Non-classical monocyte Precursor b cell Plasmacytoid dendritic cell, human Lymphocyte Natural killer cell Macrophage Classical monocyte Naive b cell

Bone marrow

73-year-old stage 53-year-old stage 61-year-old stage 82-year-old stage 70-year-old stage 55-year-old stage 51-year-old stage 69-year-old stage 60-year-old stage 67-year-old stage 71-year-old stage 44-year-old stage

B-cell non-hodgkin lymphoma Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Fibroblast Endothelial cell of vascular tree Mast cell Smooth muscle cell Chondrocyte Neural cell Muscle cell Endothelial cell of lymphatic vessel Macrophage Skeletal muscle fiber Skeletal muscle satellite cell Monocyte T cell

Calcaneal tendon Tendon of quadriceps femoris

21st week post-fertilization stage 13th week post-fertilization stage 18th week post-fertilization stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Central nervous system macrophage

Intralaminar nuclear group Primary motor cortex Perirhinal cortex Cerebellar nuclear complex Inferior temporal gyrus Dentate gyrus of hippocampal formation Cerebrocerebellum Primary visual cortex Brodmann (1909) area 35 Ventral anterior nucleus of thalamus Brodmann (1909) area 46 Subthalamic nucleus Globus pallidus Nucleus accumbens Primary somatosensory cortex Midbrain tectum Lateral nuclear group of thalamus Inferior frontal gyrus Epithalamus Cuneus cortex Retrosplenial region Medial dorsal nucleus of thalamus Medial zone of hypothalamus Putamen Lateral geniculate body Brodmann (1909) area 25 Nucleus of medulla oblongata Red nucleus Corticomedial nuclear complex Nucleus of dorsal thalamus Brodmann (1909) area 14 Pontine reticular formation Brodmann (1909) area 19 Midbrain nucleus Piriform cortex Pontine tegmentum Accessory basal amygdaloid nucleus Anterior olfactory nucleus Hypothalamus Granular insular cortex Centromedian nucleus of thalamus Brodmann (1909) area 32 Superior temporal gyrus Substantia nigra Primary auditory cortex Brodmann (1909) area 24 Cerebellar vermis Uncal ca1 Anterior cortical amygdaloid nucleus Lateral entorhinal cortex Septal nuclear complex Basolateral amygdaloid nuclear complex Spinal cord Preoptic area Middle temporal gyrus Parabrachial nucleus Brodmann (1909) area 38 Agranular insular cortex Pulvinar nucleus Body of caudate nucleus Temporal fusiform gyrus Extrastriate cortex Brodmann (1909) area 23 Medial entorhinal cortex Lateral amygdaloid nucleus Supraoptic nucleus Posterior parahippocampal gyrus Pontine nuclear group Median tuberal portion Superior parietal cortex Dorsal tegmental nucleus Substantia innominata Bed nucleus of stria terminalis Brodmann (1909) area 13 Medial geniculate body Inferior olivary complex Gray matter of midbrain Mammillary body Anterior nuclear group Central amygdaloid nucleus Subicular complex Brodmann (1909) area 43 Hippocampal field Rostral ca3 Brodmann (1909) area 40 Claustrum of brain Pretectal region Lateral posterior nucleus of thalamus

42-year-old stage 50-year-old stage 29-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Inhibitory interneuron Neuron

Substantia nigra pars compacta

90-year-old stage 78-year-old stage 74-year-old stage 83-year-old stage 82-year-old stage 49-year-old stage 70-year-old stage 75-year-old stage 79-year-old stage 89-year-old stage 76-year-old stage 91-year-old stage 92-year-old stage

Lewy body dementia Parkinson disease Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Plasmablast Double negative thymocyte Mucosal invariant t cell Effector memory cd8-positive, alpha-beta t cell Central memory cd4-positive, alpha-beta t cell Neutrophil Memory b cell Immature neutrophil Gamma-delta t cell Regulatory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Non-classical monocyte Plasmacytoid dendritic cell, human Lymphocyte Cd16-negative, cd56-bright natural killer cell, human Natural killer cell Platelet Conventional dendritic cell Classical monocyte Naive b cell Transitional stage b cell

Blood

Adult stage 27-year-old stage Third decade stage Sixth decade stage Fourth decade stage Eighth decade stage 29-year-old stage Fifth decade stage Seventh decade stage

Covid-19 Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Pvalb gabaergic interneuron

Middle temporal gyrus

Adult stage 78-year-old stage 80 year-old and over stage 72-year-old stage 83-year-old stage 85-year-old stage 81-year-old stage 82-year-old stage 86-year-old stage 70-year-old stage 75-year-old stage 50-year-old stage 89-year-old stage 68-year-old stage 29-year-old stage 77-year-old stage 69-year-old stage 88-year-old stage 87-year-old stage 60-year-old stage 80-year-old stage 84-year-old stage 43-year-old stage 65-year-old stage

Dementia Normal

Female Male

10x multiome 10x 3' v3

Nucleus