Mus musculus

Astrocyte Inhibitory interneuron Cell Oligodendrocyte precursor cell Oligodendrocyte Pericyte Macrophage Medium spiny neuron Vascular leptomeningeal cell Microglial cell T cell Neuron Endothelial cell

Cortical layer vi Striatum Cortical layer v Olfactory region Pia mater Cortical layer ii/iii Corpus callosum Brain ventricle

24-week-old stage 4-week-old stage 20-month-old stage and over

Normal

Female

Merfish

Mus musculus

Astrocyte Inhibitory interneuron Cell Oligodendrocyte precursor cell Oligodendrocyte Pericyte Macrophage Medium spiny neuron Vascular leptomeningeal cell Microglial cell T cell Neuron Endothelial cell

Cortical layer vi Striatum Cortical layer v Olfactory region Pia mater Cortical layer ii/iii Corpus callosum Brain ventricle

24-week-old stage 4-week-old stage 20-month-old stage and over

Normal

Female

Merfish

Homo sapiens

Neuroblast (sensu vertebrata) Neuroblast (sensu nematoda and protostomia) Glioblast Oligodendrocyte Radial glial cell Neuron

Striatum Cortex Forebrain Entorhinal cortex Telencephalon Hippocampal formation Occipital cortex Choroid plexus epithelium Upper layers of the cortex Caudate-putamen Lower layers of the cortex Frontal cortex

Carnegie stage 20 14th week post-fertilization stage 10th week post-fertilization stage 15th week post-fertilization stage 11th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage

Normal

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Retinal ganglion cell Off parasol ganglion cell On midget ganglion cell On parasol ganglion cell Off midget ganglion cell

Peripheral region of retina Fovea centralis Macula lutea proper Macula lutea

62-year-old stage 27-year-old stage 78-year-old stage 80 year-old and over stage 73-year-old stage 74-year-old stage 72-year-old stage 53-year-old stage 21-year-old stage 83-year-old stage 85-year-old stage 81-year-old stage 82-year-old stage 17-year-old stage 52-year-old stage 86-year-old stage 70-year-old stage 41-year-old stage Eighth decade stage 3-year-old stage 30-year-old stage 10-year-old stage 58-year-old stage 75-year-old stage 90 year-old and over stage 15-year-old stage 18-year-old stage 50-year-old stage 64-year-old stage 68-year-old stage 66-year-old stage 77-year-old stage 11-year-old stage Late adult stage 69-year-old stage 32-year-old stage 76-year-old stage 88-year-old stage 63-year-old stage 60-year-old stage 80-year-old stage Prime adult stage 84-year-old stage 25-year-old stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 60-79 year-old stage 65-year-old stage 71-year-old stage 34-year-old stage 16-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast Cortical cell of adrenal gland Schwann cell Kidney cell Neuroblast (sensu vertebrata) Dendritic cell B cell Hepatocyte Macrophage T cell Endothelial cell

Adrenal gland Neck Liver Chest Abdomen Cervical lymph node Lymph node

12-month-old stage 13-year-old stage 18-month-old stage 7-year-old stage 4-year-old stage 12-year-old stage 3-year-old stage 2-year-old stage 15-month-old stage 5-year-old stage 20-month-old stage 6-month-old stage 21-month-old stage 16-month-old stage

Neuroblastoma

Female Male

10x 3' v3

Nucleus

Macaca mulatta

Gabaergic neuron

Primary motor cortex Perirhinal cortex Inferior temporal gyrus Midbrain Cerebrocerebellum Primary visual cortex Nucleus accumbens Dorsolateral prefrontal cortex Primary somatosensory cortex Medial dorsal nucleus of thalamus Lateral geniculate body Ventral lateral nucleus of thalamus Amygdala Brodmann (1909) area 19 Inferior parietal cortex Primary auditory cortex Cerebellar vermis Pons Entorhinal cortex Hippocampal formation Anterior cingulate cortex Prefrontal cortex Superior parietal cortex Superior temporal sulcus Corpus callosum Medulla oblongata Head of caudate nucleus

Prime adult stage Juvenile stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Macaca mulatta

Cerebellar neuron

Primary motor cortex Perirhinal cortex Inferior temporal gyrus Midbrain Cerebrocerebellum Primary visual cortex Nucleus accumbens Dorsolateral prefrontal cortex Primary somatosensory cortex Medial dorsal nucleus of thalamus Lateral geniculate body Ventral lateral nucleus of thalamus Amygdala Brodmann (1909) area 19 Inferior parietal cortex Primary auditory cortex Cerebellar vermis Pons Entorhinal cortex Hippocampal formation Anterior cingulate cortex Prefrontal cortex Superior parietal cortex Superior temporal sulcus Corpus callosum Medulla oblongata Head of caudate nucleus

Prime adult stage Juvenile stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Iga plasma cell Fibroblast Enteroendocrine cell Schwann cell Germinal center b cell Mast cell Enterocyte Igg plasma cell Granulocyte Smooth muscle cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Dendritic cell Colon endothelial cell Gamma-delta t cell T-helper 17 cell Endothelial tip cell Capillary endothelial cell Pericyte Mature conventional dendritic cell Myofibroblast cell Activated cd4-positive, alpha-beta t cell Colon goblet cell Plasmacytoid dendritic cell Goblet cell Glandular secretory epithelial cell Cd8-positive, alpha-beta t cell Endothelial cell of venule Effector cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Natural killer cell Macrophage Tuft cell of colon Mature b cell Colonocyte Group 3 innate lymphoid cell Conventional dendritic cell Monocyte Intestinal epithelial cell Mature nk t cell Cd8-positive, alpha-beta memory t cell Cd4-positive, alpha-beta t cell T cell T follicular helper cell Stem cell Endothelial cell of artery

Colorectum

90-year-old stage 35-year-old stage 62-year-old stage 78-year-old stage 73-year-old stage 72-year-old stage 53-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage 82-year-old stage 49-year-old stage 42-year-old stage 36-year-old stage 52-year-old stage 48-year-old stage 70-year-old stage 45-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 50-year-old stage 51-year-old stage 89-year-old stage 64-year-old stage 77-year-old stage 69-year-old stage 76-year-old stage 60-year-old stage 84-year-old stage 56-year-old stage 91-year-old stage 67-year-old stage 71-year-old stage 47-year-old stage

Colon adenocarcinoma Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Secretory cell Fibroblast Pancreatic d cell Pancreatic pp cell Enteroendocrine cell Regular atrial cardiac myocyte Kupffer cell Pancreatic ductal cell Mature alpha-beta t cell Professional antigen presenting cell Kidney capillary endothelial cell Kidney loop of henle thick ascending limb epithelial cell Double negative thymocyte Schwann cell Kidney cell Luminal epithelial cell of mammary gland Kidney loop of henle ascending limb epithelial cell Keratinocyte Multiciliated columnar cell of tracheobronchial tree Myeloid cell Kidney proximal convoluted tubule epithelial cell Pancreatic a cell Astrocyte Pancreatic acinar cell Macrophage dendritic cell progenitor Kidney collecting duct epithelial cell Endothelial cell of coronary artery Mast cell Langerhans cell Cardiac valve cell Epithelial cell of proximal tubule Regular ventricular cardiac myocyte Granulocyte Vein endothelial cell Mesenchymal stem cell Epidermal cell Intermediate monocyte Endocardial cell Alveolar macrophage Naive t cell Lymphoid lineage restricted progenitor cell Smooth muscle cell Myeloid dendritic cell Hematopoietic precursor cell Basophil Neutrophil Oligodendrocyte precursor cell Dn3 thymocyte Epithelial cell Stromal cell Proerythroblast Smooth muscle cell of trachea Enterocyte of epithelium of large intestine Plasma cell Early pro-b cell Immature b cell Oligodendrocyte Cardiac muscle cell Basal cell of epidermis Dendritic cell Basal epithelial cell of tracheobronchial tree B cell Regulatory t cell Mesenchymal cell Chondrocyte Circulating fibrocyte Blood cell Large intestine goblet cell Fibroblast of lung Tuft cell Mucus secreting cell Bergmann glial cell Myeloid leukocyte Pericyte Late pro-b cell Club cell Stem cell of epidermis Smooth muscle cell of the pulmonary artery Neuroepithelial stem cell Hepatocyte Hematopoietic stem cell Non-classical monocyte Precursor b cell Aortic endothelial cell Pulmonary alveolar type 2 cell Plasmacytoid dendritic cell Kidney interstitial fibroblast Epithelial cell of thymus Interneuron Brain pericyte Lymphocyte Respiratory basal cell Granulocytopoietic cell Kidney proximal straight tubule epithelial cell Leukocyte Duct epithelial cell Cd8-positive, alpha-beta t cell Cell of skeletal muscle Promonocyte Kidney distal convoluted tubule epithelial cell Mesangial cell Megakaryocyte-erythroid progenitor cell Pulmonary alveolar type 1 cell Ependymal cell Endothelial cell of lymphatic vessel Lung macrophage Granulocyte monocyte progenitor cell Kidney cortex artery cell Natural killer cell Endothelial cell of hepatic sinusoid Macrophage Erythroid progenitor cell, mammalian Hepatic stellate cell Neuroendocrine cell Cardiac neuron Bladder urothelial cell Skeletal muscle satellite cell Fenestrated endothelial cell Erythroblast Bronchial smooth muscle cell Erythrocyte Neural stem cell Tuft cell of large intestine Type b pancreatic cell Mesenchymal stem cell of adipose tissue Medium spiny neuron Thymocyte Monocyte Intestinal crypt stem cell Pulmonary interstitial fibroblast Mature nk t cell Basal cell Classical monocyte Epithelial cell of large intestine Kidney collecting duct principal cell Adventitial cell Pancreatic stellate cell Cd4-positive, alpha-beta t cell Microglial cell Fibroblast of cardiac tissue T cell Neuron Keratinocyte stem cell Naive b cell Dn4 thymocyte Immature nk t cell Immature t cell Pulmonary neuroendocrine cell Endothelial cell Plasmatocyte Bladder cell

Skin of body Trachea Brown adipose tissue Lung Aorta Subcutaneous adipose tissue Mesenteric fat pad Liver Bladder lumen Gonadal fat pad Brain Limb muscle Large intestine Bone marrow Tongue Kidney Adipose tissue Spleen Thymus Pancreas Heart Diaphragm Mammary gland

4-week-old stage 20-month-old stage and over 3-month-old stage 18-month-old stage

Normal

Female Male

Smart-seq2 10x 3' v2

Cell

Homo sapiens

Fibroblast Hematopoietic multipotent progenitor cell Myeloid cell Mast cell Cd8-positive, cd28-negative, alpha-beta regulatory t cell Naive t cell Melanocyte Malignant cell Plasma cell Dendritic cell B cell Regulatory t cell T-helper 17 cell Myofibroblast cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Epithelial cell of thymus Lymphocyte Cd8-positive, alpha-beta t cell Effector cd8-positive, alpha-beta t cell Central memory cd8-positive, alpha-beta t cell Macrophage Activated cd8-positive, alpha-beta t cell, human Monocyte Mature nk t cell Cd4-positive, alpha-beta t cell Microglial cell T cell T follicular helper cell Endothelial cell

Skin of body Skin of forehead Skin of external ear Arm skin Liver Brain Nose skin Kidney Skin of calf Skin of neck Skin of scalp Skin of cheek Breast Skin of knee

54-year-old stage Adult stage 62-year-old stage 80 year-old and over stage 73-year-old stage 74-year-old stage 72-year-old stage 83-year-old stage 85-year-old stage Postnatal stage 81-year-old stage 61-year-old stage 57-year-old stage Sixth decade stage Fourth decade stage 52-year-old stage 86-year-old stage 41-year-old stage Eighth decade stage 58-year-old stage 79-year-old stage 64-year-old stage 68-year-old stage 77-year-old stage Late adult stage 69-year-old stage 76-year-old stage Fifth decade stage 63-year-old stage 60-year-old stage 80-year-old stage Prime adult stage 37-year-old stage Middle aged stage 67-year-old stage 43-year-old stage 60-79 year-old stage 65-year-old stage 71-year-old stage Seventh decade stage 47-year-old stage

Her2 positive breast carcinoma Melanoma Triple-negative breast carcinoma Hepatocellular carcinoma Squamous cell carcinoma Basal cell carcinoma Metastatic melanoma Intrahepatic cholangiocarcinoma Estrogen-receptor positive breast cancer Nonpapillary renal cell carcinoma

Female Male

10x 5' transcription profiling 10x 3' v3 Smart-seq2 10x 3' v2

Cell

Homo sapiens

Enteroendocrine cell Schwann cell Colon epithelial cell Enterocyte Smooth muscle cell Intestinal tuft cell Hematopoietic cell Epithelial cell Stromal cell Interstitial cell of cajal Colon endothelial cell Paneth cell Pericyte Goblet cell Mesodermal cell Ciliated cell Basal cell Mesothelial cell Neuron M cell of gut Stem cell Endothelial cell

Ileum Intestine Duodenum Colon

Normal

Sort-seq 10x 3' v3 Seq-well s3 10x 5' v2 10x 3' v2

Cell Nucleus

Homo sapiens

Mammary gland epithelial cell Luminal hormone-sensing cell of mammary gland Basal-myoepithelial cell of mammary gland Luminal adaptive secretory precursor cell of mammary gland

Breast

35-year-old stage 39-year-old stage 62-year-old stage 27-year-old stage 53-year-old stage 19-year-old stage 21-year-old stage 57-year-old stage 36-year-old stage 52-year-old stage 48-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 23-year-old stage 58-year-old stage 29-year-old stage 33-year-old stage 28-year-old stage 31-year-old stage 63-year-old stage 25-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 24-year-old stage 20-year-old stage 65-year-old stage 34-year-old stage

Normal

Female

10x 3' v3

Cell