Homo sapiens

Oligodendrocyte

Cranial nerve ii Optic disc

54-year-old stage 62-year-old stage 27-year-old stage 74-year-old stage 72-year-old stage 53-year-old stage 21-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage 82-year-old stage 42-year-old stage 17-year-old stage 52-year-old stage 70-year-old stage 45-year-old stage 3-year-old stage 30-year-old stage 10-year-old stage 58-year-old stage 75-year-old stage 90 year-old and over stage 15-year-old stage 18-year-old stage 50-year-old stage 64-year-old stage 68-year-old stage 77-year-old stage 11-year-old stage 33-year-old stage 69-year-old stage 32-year-old stage 76-year-old stage 63-year-old stage 60-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 67-year-old stage 43-year-old stage 65-year-old stage 71-year-old stage 34-year-old stage 16-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Astrocyte Leptomeningeal cell Gabaergic neuron Smooth muscle cell Oligodendrocyte Pericyte Glutamatergic neuron Microglial cell Endothelial cell

Primary motor cortex

Prime adult stage

Normal

Male

Merfish

Homo sapiens

Effector memory cd4-positive, alpha-beta t cell Mast cell Igg plasma cell Effector memory cd8-positive, alpha-beta t cell Naive t cell Myeloid dendritic cell Exhausted t cell Memory b cell Cd8-positive, alpha-beta regulatory t cell Cd4-positive, cd25-positive, ccr4-positive, alpha-beta regulatory t cell Plasmacytoid dendritic cell Cd4-positive helper t cell Natural killer cell Macrophage Cycling macrophage Conventional dendritic cell Cycling t cell T follicular helper cell

Breast

54-year-old stage 35-year-old stage Adult stage 62-year-old stage 80 year-old and over stage 73-year-old stage Ninth decade stage 83-year-old stage 85-year-old stage 61-year-old stage 57-year-old stage Sixth decade stage 82-year-old stage 49-year-old stage 42-year-old stage 36-year-old stage 52-year-old stage 70-year-old stage 38-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage Eighth decade stage 30-year-old stage 55-year-old stage 58-year-old stage 50-year-old stage 79-year-old stage 64-year-old stage 29-year-old stage 66-year-old stage Late adult stage 69-year-old stage 32-year-old stage Fifth decade stage 88-year-old stage 63-year-old stage 60-year-old stage 80-year-old stage Prime adult stage 84-year-old stage 25-year-old stage 37-year-old stage Middle aged stage 46-year-old stage 67-year-old stage 43-year-old stage 60-79 year-old stage 65-year-old stage 71-year-old stage Seventh decade stage 34-year-old stage 47-year-old stage

Invasive lobular breast carcinoma Breast apocrine carcinoma Her2 positive breast carcinoma Breast mucinous carcinoma Breast carcinoma Triple-negative breast carcinoma Invasive ductal breast carcinoma Invasive tubular breast carcinoma Breast cancer Metaplastic breast carcinoma Estrogen-receptor positive breast cancer

Female Male

10x 5' transcription profiling 10x 3' v3 10x 5' v2 10x 5' v1 10x 3' v2

Cell

Homo sapiens

Astrocyte Retinal astrocyte

Cranial nerve ii Optic disc

54-year-old stage 62-year-old stage 27-year-old stage 74-year-old stage 72-year-old stage 53-year-old stage 21-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage Newborn stage (0-28 days) 82-year-old stage 42-year-old stage 17-year-old stage 52-year-old stage 70-year-old stage 45-year-old stage 3-year-old stage 30-year-old stage 10-year-old stage 58-year-old stage 75-year-old stage 90 year-old and over stage 15-year-old stage 18-year-old stage 50-year-old stage 64-year-old stage 68-year-old stage 77-year-old stage 11-year-old stage 33-year-old stage 69-year-old stage 32-year-old stage 76-year-old stage 63-year-old stage 60-year-old stage 25-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 67-year-old stage 43-year-old stage 65-year-old stage 71-year-old stage 34-year-old stage 16-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Plasmablast Germinal center b cell Memory b cell Plasma cell B cell Precursor b cell Naive b cell

Lung Mesenteric lymph node Jejunal epithelium Blood Epithelial lining fluid Bone marrow Spleen Thoracic lymph node Jejunum lamina propria Inguinal lymph node

27-year-old stage 73-year-old stage Third decade stage Sixth decade stage Fourth decade stage 48-year-old stage Eighth decade stage 23-year-old stage 75-year-old stage 64-year-old stage 68-year-old stage 33-year-old stage Fifth decade stage 25-year-old stage 56-year-old stage 67-year-old stage 20-year-old stage

Normal

Female Male

10x 3' v3 10x 5' v2

Cell

Homo sapiens

Secretory cell Alveolar type 1 fibroblast cell Helper t cell Mucus secreting cell of tracheobronchial tree submucosal gland Mesothelial cell of pleura Secondary crest myofibroblast Mast cell Vein endothelial cell Alveolar macrophage Lung secretory cell Plasma cell B cell Regulatory t cell Lung megakaryocyte Tracheobronchial smooth muscle cell Vascular associated smooth muscle cell Alveolar capillary type 2 endothelial cell Pericyte Mature conventional dendritic cell Alveolar capillary type 1 endothelial cell Non-classical monocyte Pulmonary alveolar type 2 cell Plasmacytoid dendritic cell Goblet cell Alveolar adventitial fibroblast Pulmonary alveolar type 1 cell Natural killer cell Conventional dendritic cell Ciliated cell Basal cell Lung interstitial macrophage Classical monocyte Vein endothelial cell of respiratory system Endothelial cell of respiratory system lymphatic vessel Brush cell of tracheobronchial tree Serous secreting cell Cd8-positive, alpha-beta cytotoxic t cell Pulmonary neuroendocrine cell Endothelial cell of artery

Middle lobe of right lung

11-month-old stage 7-month-old stage 14-month-old stage 12-month-old stage 18-month-old stage 3-year-old stage 10-month-old stage 13-month-old stage 5-month-old stage 15-month-old stage 4-month-old stage 19-month-old stage 20-month-old stage 6-month-old stage 21-month-old stage 8-month-old stage

Bronchopulmonary dysplasia Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Iga plasma cell Fibroblast Epithelial cell of proximal tubule segment 3 Innate lymphoid cell Effector memory cd4-positive, alpha-beta t cell Class switched memory b cell Kidney loop of henle thick ascending limb epithelial cell Mucosal invariant t cell Kidney loop of henle ascending limb epithelial cell Mast cell Igg plasma cell Effector memory cd8-positive, alpha-beta t cell Unswitched memory b cell Epithelial cell of proximal tubule Podocyte Renal alpha-intercalated cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Epithelial cell Plasma cell Collagen secreting cell Mhc-ii-positive classical monocyte B cell Gamma-delta t cell Epithelial cell of proximal tubule segment 1 Naive thymus-derived cd4-positive, alpha-beta t cell Renal beta-intercalated cell Pericyte Naive thymus-derived cd8-positive, alpha-beta t cell Kidney connecting tubule principal cell Non-classical monocyte Plasmacytoid dendritic cell Cd8-positive, alpha-beta t cell Kidney distal convoluted tubule epithelial cell Endothelial cell of lymphatic vessel Natural killer cell Macrophage Activated type ii nk t cell Kidney pelvis urothelial cell Conventional dendritic cell Classical monocyte Kidney collecting duct principal cell Cd4-positive, alpha-beta t cell Naive b cell Endothelial cell

Adrenal tissue Blood Kidney Perirenal fat Vein

Sixth decade stage Eighth decade stage Fifth decade stage Seventh decade stage

Kidney oncocytoma Kidney benign neoplasm Nonpapillary renal cell carcinoma Normal

Female Male

10x 5' transcription profiling

Cell

Homo sapiens

Retinal ganglion cell H1 horizontal cell Retinal rod cell Astrocyte H2 horizontal cell Gabaergic amacrine cell Parasol ganglion cell of retina Amacrine cell Retinal bipolar neuron S cone cell Retinal pigment epithelial cell Glycinergic amacrine cell Starburst amacrine cell Midget ganglion cell of retina Rod bipolar cell Retinal cone cell Mueller cell Microglial cell

Chorioretinal region Peripheral region of retina Fovea centralis Retinal neural layer Macula lutea proper

54-year-old stage Adult stage 78-year-old stage 74-year-old stage 53-year-old stage 82-year-old stage 42-year-old stage 86-year-old stage 89-year-old stage 64-year-old stage 68-year-old stage 69-year-old stage 60-year-old stage 80-year-old stage 65-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Innate lymphoid cell Enteroendocrine cell Effector memory cd4-positive, alpha-beta t cell Transit amplifying cell Follicular b cell Germinal center b cell Mast cell Enterocyte Effector memory cd8-positive, alpha-beta t cell Glial cell Gastrointestinal tract (lamina propria) macrophage of large intestine Vein endothelial cell Central memory cd4-positive, alpha-beta t cell Stromal cell Memory b cell Enterocyte of epithelium of large intestine Plasma cell T-helper 1 cell B cell Gamma-delta t cell Regulatory t cell T-helper 17 cell Capillary endothelial cell Paneth cell Pericyte Myofibroblast cell Goblet cell Endothelial cell of lymphatic vessel Natural killer cell Macrophage Tuft cell of colon Best4+ enterocyte Conventional dendritic cell Monocyte Naive b cell T follicular helper cell Stem cell Endothelial cell of artery

Ascending colon Sigmoid colon Transverse colon Caecum Colonic epithelium Ileum Vermiform appendix Descending colon Large intestine Small intestine Jejunum Rectum Duodenum

Adult stage 53-year-old stage Third decade stage Sixth decade stage 45-year-old stage Eighth decade stage 29-year-old stage Fifth decade stage Seventh decade stage

Normal

Female Male

10x 3' v3 10x 3' v1 10x 5' v2 10x 3' v2

Cell

Homo sapiens

Cd14-positive, cd16-positive monocyte Pre-conventional dendritic cell Effector memory cd4-positive, alpha-beta t cell Basophil mast progenitor cell Common myeloid progenitor Hematopoietic multipotent progenitor cell Large pre-b-ii cell Effector memory cd8-positive, alpha-beta t cell Cd14-positive monocyte Cd4-positive, cd25-positive, alpha-beta regulatory t cell Central memory cd4-positive, alpha-beta t cell Pro-b cell Polychromatophilic erythroblast Small pre-b-ii cell Plasma cell Immature b cell Dendritic cell Megakaryocyte Erythroid progenitor cell Naive thymus-derived cd4-positive, alpha-beta t cell Late pro-b cell Naive thymus-derived cd8-positive, alpha-beta t cell Hematopoietic stem cell Plasmacytoid dendritic cell, human Basophilic erythroblast Promonocyte Megakaryocyte-erythroid progenitor cell Cd16-negative, cd56-bright natural killer cell, human Granulocyte monocyte progenitor cell Central memory cd8-positive, alpha-beta t cell Natural killer cell Mature b cell Orthochromatic erythroblast Conventional dendritic cell Cd8-positive, alpha-beta memory t cell T cell Megakaryocyte progenitor cell Stromal cell of bone marrow Hematopoietic oligopotent progenitor cell Common lymphoid progenitor

Bone marrow

35-year-old stage 39-year-old stage 26-year-old stage 19-year-old stage 57-year-old stage 36-year-old stage 52-year-old stage 41-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 58-year-old stage 50-year-old stage 29-year-old stage 66-year-old stage Late adult stage 32-year-old stage 28-year-old stage Young adult stage 31-year-old stage 60-year-old stage Prime adult stage 84-year-old stage 56-year-old stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

Cholangiocyte Neutrophil B cell Hepatic portal fibroblast Hepatocyte Plasmacytoid dendritic cell Macrophage Hepatic stellate cell T cell Endothelial cell

Normal

10x 3' v3

Homo sapiens

Mucosal invariant t cell Cd16-positive, cd56-dim natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Cd4-positive, alpha-beta memory t cell Gamma-delta t cell Regulatory t cell T-helper 17 cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Cd16-negative, cd56-bright natural killer cell, human Group 3 innate lymphoid cell Cd8-positive, alpha-beta memory t cell Cycling t cell T follicular helper cell

Epithelium of rectum Ileum lamina propria Ileal epithelium Epithelium of esophagus Stomach Ascending colon Sigmoid colon Transverse colon Pyloric antrum Caecum Colonic epithelium Colonic mucosa Mesenteric lymph node Ileum Vermiform appendix Descending colon Rectosigmoid junction Small intestine Duodenal epithelium Periodontium Body of stomach Intestine Buccal mucosa Esophagus Jejunum Epithelium of stomach Rectum Labial gland Duodenum Pylorus Gingiva Epithelium of small intestine Parotid gland Lamina propria of mucosa of colon Lamina propria of small intestine Colon

54-year-old stage 35-year-old stage Adult stage 39-year-old stage 62-year-old stage Carnegie stage 19 74-year-old stage 26-year-old stage 72-year-old stage 9-year-old stage 21st week post-fertilization stage Third decade stage 10th week post-fertilization stage 21-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage Juvenile stage (5-14 yo) 13-year-old stage Sixth decade stage Newborn stage (0-28 days) 4-year-old stage 16th week post-fertilization stage Fourth decade stage 52-year-old stage 86-year-old stage 48-year-old stage Carnegie stage 22 19th week post-fertilization stage 70-year-old stage 6-year-old stage 12-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage Eighth decade stage 30-year-old stage 10-year-old stage 2-month-old stage 55-year-old stage 23-year-old stage 58-year-old stage 14-year-old stage 2-year-old stage 75-year-old stage 22-year-old stage 50-year-old stage 51-year-old stage 68-year-old stage 29-year-old stage 66-year-old stage 15th week post-fertilization stage 77-year-old stage 11-year-old stage 11th week post-fertilization stage 13th week post-fertilization stage 33-year-old stage 69-year-old stage 32-year-old stage 12th week post-fertilization stage 28-year-old stage 76-year-old stage Young adult stage 5-year-old stage Fifth decade stage 31-year-old stage Carnegie stage 17 87-year-old stage 63-year-old stage 60-year-old stage 80-year-old stage Prime adult stage 18th week post-fertilization stage 84-year-old stage 56-year-old stage 37-year-old stage Pediatric stage 9th week post-fertilization stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 65-year-old stage 17th week post-fertilization stage Seventh decade stage 44-year-old stage 34-year-old stage

Crohn disease Inflammatory bowel disease Colorectal cancer Gastric cancer Normal Ulcerative colitis

Female Male

10x 5' transcription profiling 10x 3' v3 10x 3' v1 10x 5' v2 10x 5' v1 10x 3' v2

Cell