Mus musculus

Neural stem cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Microglial cell Leptomeningeal cell Pericyte Astrocyte

Secondary somatosensory cortex Lateral septal complex Piriform cortex Hippocampal field Pallidum Orbitofrontal cortex Olfactory cortex Cerebral cortex Nucleus accumbens Primary somatosensory cortex Anterior olfactory nucleus Primary auditory cortex Primary motor cortex Caudate-putamen Dentate gyrus of hippocampal formation Anterior cerebral artery

Prime adult stage

Normal

Male

Scatac-seq

Nucleus

Homo sapiens

T cell Neutrophil Natural killer cell Endothelial cell Mast cell Smooth muscle cell Macrophage Plasma cell B cell Monocyte Fibroblast Dendritic cell

Coronary artery Femoral artery Carotid artery segment

66-year-old stage 75-year-old stage 65-year-old stage 89-year-old stage 87-year-old stage 71-year-old stage 54-year-old stage 82-year-old stage 80-year-old stage 81-year-old stage 74-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 46-year-old stage 78-year-old stage 76-year-old stage 79-year-old stage 83-year-old stage

Atherosclerosis

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Glioblast Cell Erythrocyte Oligodendrocyte Neuroblast (sensu nematoda and protostomia) Neuroplacodal cell Neural crest cell Macrophage Neuroblast (sensu vertebrata) Radial glial cell Neuron Fibroblast

Midbrain Midbrain tectum Cerebellar peduncular complex

13th week post-fertilization stage 15th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 16 Carnegie stage 15

Normal

10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Natural killer cell Erythrocyte Gamma-delta t cell Cd8-alpha-alpha-positive, alpha-beta intraepithelial t cell Endothelial cell Alpha-beta t cell Mast cell Cd8-positive, alpha-beta t cell Cortical thymic epithelial cell Double-positive, alpha-beta thymocyte Plasmacytoid dendritic cell Precursor b cell Lymphocyte Cd8-positive, alpha-beta memory t cell Group 3 innate lymphoid cell Macrophage Memory b cell Regulatory t cell Plasma cell Cd4-positive, alpha-beta t cell Megakaryocyte Cd4-positive, alpha-beta memory t cell Medullary thymic epithelial cell Progenitor cell Monocyte Early t lineage precursor Vascular associated smooth muscle cell Naive b cell Double negative thymocyte Epithelial cell of thymus Fibroblast Dendritic cell

Thymus

13th week post-fertilization stage 2-year-old stage 3-month-old stage 15th week post-fertilization stage 17th week post-fertilization stage 15-month-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 9th week post-fertilization stage 6-month-old stage 10th week post-fertilization stage Organogenesis stage 10-month-old stage Fourth decade stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Normal

Female Male

10x 5' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Conjunctival epithelial cell Epithelial cell

Corneal epithelium Cornea Tunica fibrosa of eyeball Sclera Substantia propria of cornea Ocular surface region Corneo-scleral junction

69-year-old stage 75-year-old stage 13-year-old stage 34-year-old stage 65-year-old stage 43-year-old stage 87-year-old stage 53-year-old stage 61-year-old stage 2-year-old stage 48-year-old stage 39-year-old stage 55-year-old stage 84-year-old stage 51-year-old stage 72-year-old stage 74-year-old stage 16-year-old stage 25-year-old stage 67-year-old stage 90 year-old and over stage 32-year-old stage 77-year-old stage 33-year-old stage 64-year-old stage Postnatal stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 1-year-old stage 22-year-old stage Newborn stage (0-28 days) Eighth decade stage 83-year-old stage 11-year-old stage 27-year-old stage 10-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Germinal center b cell Igm plasma cell Pro-b cell Iga plasma cell Igg plasma cell Precursor b cell Memory b cell Plasmablast Naive b cell

Ascending colon Colonic mucosa Stomach Duodenum Colonic epithelium Ileal epithelium Rectosigmoid junction Pyloric antrum Caecum Small intestine Gingiva Ileum Ileum lamina propria Lamina propria of mucosa of colon Colon Epithelium of rectum Epithelium of esophagus Intestine Buccal mucosa Body of stomach Vermiform appendix Epithelium of small intestine Pylorus Rectum Esophagus Jejunum Duodenal epithelium Transverse colon Periodontium Parotid gland Descending colon Sigmoid colon Labial gland Epithelium of stomach Mesenteric lymph node

66-year-old stage 69-year-old stage 37-year-old stage 75-year-old stage Pediatric stage 19th week post-fertilization stage 21-year-old stage 13-year-old stage 34-year-old stage 65-year-old stage 26-year-old stage 43-year-old stage Sixth decade stage 13th week post-fertilization stage 85-year-old stage 61-year-old stage 2-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 29-year-old stage 56-year-old stage Fifth decade stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 50-year-old stage 80-year-old stage 28-year-old stage 51-year-old stage 17th week post-fertilization stage 57-year-old stage 12-year-old stage 72-year-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 81-year-old stage 9th week post-fertilization stage 74-year-old stage 9-year-old stage 10th week post-fertilization stage 14-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage Seventh decade stage 58-year-old stage 59-year-old stage Adult stage 67-year-old stage 18th week post-fertilization stage 2-month-old stage 32-year-old stage 77-year-old stage 33-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage Fourth decade stage Newborn stage (0-28 days) 63-year-old stage Eighth decade stage 76-year-old stage Prime adult stage 5-year-old stage 11-year-old stage 6-year-old stage Young adult stage 10-year-old stage 4-year-old stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Gastric cancer Inflammatory bowel disease Colorectal cancer Ulcerative colitis Normal Crohn disease

Female Male

10x 3' v1 10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v3 10x 3' v2

Cell

Mus musculus

Glioblast Blood vessel endothelial cell Glutamatergic neuron Erythrocyte Oligodendrocyte precursor cell Hypendymal cell Vascular leptomeningeal cell Ependymal cell Microglial cell Neuron Gabaergic neuron Neural progenitor cell

Diencephalon

Theiler stage 22 Theiler stage 24 Theiler stage 26 Theiler stage 20

Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Glutamatergic neuron Oligodendrocyte precursor cell Brain vascular cell Microglial cell Forebrain radial glial cell Neuron Neuronal-restricted precursor Gabaergic neuron

Brain

13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 20th week post-fertilization stage 17th week post-fertilization stage 12th week post-fertilization stage 16th week post-fertilization stage 10th week post-fertilization stage 18th week post-fertilization stage 11th week post-fertilization stage

Complete trisomy 21 Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Retinal ganglion cell Retinal pigment epithelial cell Retinal cone cell Retina horizontal cell Retinal progenitor cell Lens fiber cell

Optic cup

Adult stage

Normal Open-angle glaucoma

Female Male

10x 3' v2

Cell

Homo sapiens

T cell Gamma-delta t cell Double-positive, alpha-beta thymocyte Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Regulatory t cell Plasmablast Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Naive b cell Double negative thymocyte Memory t cell

Blood

66-year-old stage 37-year-old stage 71-year-old stage 53-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 30-year-old stage 55-year-old stage 84-year-old stage 50-year-old stage 51-year-old stage 57-year-old stage 74-year-old stage 49-year-old stage 24-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 32-year-old stage 77-year-old stage 45-year-old stage 70-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 40-year-old stage

Covid-19 Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Muscle cell Schwann cell Melanocyte Epithelial cell Endothelial cell of vascular tree Lymphocyte Mural cell Myeloid cell Odontoblast Fibroblast

Molar dental pulp Gingiva Minor salivary gland Sublingual gland Mucosa of lip Buccal mucosa Hard palate Dental pulp Submandibular gland Mucosa of dorsum of tongue Periodontium Parotid gland Soft palate

69-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 26-year-old stage Sixth decade stage 53-year-old stage 61-year-old stage 68-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 29-year-old stage 56-year-old stage 28-year-old stage 51-year-old stage 57-year-old stage 24-year-old stage 35-year-old stage Seventh decade stage 59-year-old stage 32-year-old stage 33-year-old stage 62-year-old stage 31-year-old stage Fourth decade stage 22-year-old stage 20-year-old stage 40-year-old stage Young adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Endothelial cell Mast cell Pancreatic acinar cell Pancreatic pp cell Schwann cell Leukocyte Pancreatic a cell Pancreatic d cell Pancreatic stellate cell Type b pancreatic cell Pancreatic epsilon cell Pancreatic ductal cell

Islet of langerhans

66-year-old stage 37-year-old stage 21-year-old stage 34-year-old stage 42-year-old stage 26-year-old stage 53-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 48-year-old stage 30-year-old stage 38-year-old stage 55-year-old stage 50-year-old stage 51-year-old stage 57-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 32-year-old stage 45-year-old stage 62-year-old stage 60-year-old stage 63-year-old stage 40-year-old stage

Prediabetes syndrome Normal Type 2 diabetes mellitus

Female Male

10x 3' v3 10x 3' v2

Cell