Homo sapiens

Cytotoxic t cell Innate lymphoid cell Helper t cell Schwann cell Inflammatory macrophage Endothelial cell of vascular tree Keratinocyte Mast cell Langerhans cell Melanocyte Plasma cell Dendritic cell Regulatory t cell Monocyte-derived dendritic cell Pericyte Skin fibroblast Endothelial cell of lymphatic vessel Natural killer cell Macrophage Conventional dendritic cell

Dermis Skin epidermis

Adult stage

Normal

Female

10x 3' v2

Cell

Homo sapiens

Vein endothelial cell Smooth muscle cell Capillary endothelial cell Pericyte Endothelial cell of lymphatic vessel Mesothelial cell Endothelial cell Endothelial cell of artery

Heart left ventricle Apex of heart Left cardiac atrium Interventricular septum Right cardiac atrium Heart right ventricle

Sixth decade stage Eighth decade stage Fifth decade stage Seventh decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Peritubular capillary endothelial cell Kidney loop of henle thin descending limb epithelial cell Kidney loop of henle thick ascending limb epithelial cell Parietal epithelial cell Myeloid cell Glomerular capillary endothelial cell Dendritic cell, human Epithelial cell of proximal tubule Podocyte Vasa recta cell Kidney connecting tubule epithelial cell Mural cell B cell Kidney inner medulla collecting duct epithelial cell Vascular associated smooth muscle cell Non-classical monocyte Kidney interstitial fibroblast Kidney loop of henle thin ascending limb epithelial cell Lymphocyte Kidney distal convoluted tubule epithelial cell Endothelial cell of lymphatic vessel Natural killer cell Renal medullary fibroblast Kidney collecting duct intercalated cell Kidney arterial blood vessel cell Conventional dendritic cell Classical monocyte Kidney collecting duct principal cell T cell

Cortex of kidney Renal papilla Kidney Renal medulla Renal pelvis

54-year-old stage 35-year-old stage 39-year-old stage 62-year-old stage 74-year-old stage 72-year-old stage 53-year-old stage 61-year-old stage 57-year-old stage 49-year-old stage 42-year-old stage 52-year-old stage 48-year-old stage 70-year-old stage 40-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage Eighth decade stage 30-year-old stage 58-year-old stage 50-year-old stage 64-year-old stage 68-year-old stage 29-year-old stage 66-year-old stage 69-year-old stage 76-year-old stage 31-year-old stage 63-year-old stage 60-year-old stage 56-year-old stage 46-year-old stage 67-year-old stage 43-year-old stage 71-year-old stage Seventh decade stage 44-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3 10x 5' v1 10x 3' v2

Nucleus Cell

Mus musculus

Fibroblast Pancreatic d cell Pancreatic pp cell Kupffer cell Exocrine cell Schwann cell Pancreatic a cell Granulocyte Endocardial cell Neutrophil Cardiac muscle cell Dendritic cell Kidney tubule cell B cell Circulating fibrocyte Pericyte Hepatocyte Natural killer cell Macrophage Hepatic stellate cell Type b pancreatic cell Monocyte Mature nk t cell T cell Endothelial cell

Liver Blood Kidney Pancreas Heart

2-month-old stage

Myocardial infarction Normal

Male

10x 3' v3

Cell

Homo sapiens

Iga plasma cell Fibroblast Innate lymphoid cell Lung pericyte Plasmablast Airway submucosal gland duct basal cell Mucosal invariant t cell Mast cell Igg plasma cell Effector memory cd8-positive, alpha-beta t cell Lung perichondrial fibroblast Bronchus fibroblast of lung Vein endothelial cell Myelinating schwann cell Metallothionein-positive alveolar macrophage Cd14-positive monocyte Alveolar macrophage Smooth muscle cell Lung secretory cell Epithelial cell Memory b cell Lung resident memory cd8-positive, alpha-beta t cell Dendritic cell Gamma-delta t cell Regulatory t cell Blood vessel endothelial cell Chondrocyte Non-myelinating schwann cell Megakaryocyte Serous secreting cell of bronchus submucosal gland Lung resident memory cd4-positive, alpha-beta t cell Myoepithelial cell Fibroblast of lung Naive thymus-derived cd4-positive, alpha-beta t cell Myofibroblast cell Club cell Smooth muscle cell of the pulmonary artery Pulmonary alveolar type 2 cell Plasmacytoid dendritic cell Goblet cell Pulmonary alveolar type 1 cell Effector cd4-positive, alpha-beta t cell Blood vessel smooth muscle cell Endothelial cell of lymphatic vessel Lung macrophage Natural killer cell Deuterosomal cell Neuroendocrine cell Erythrocyte Conventional dendritic cell Ciliated cell Monocyte Basal cell Lung interstitial macrophage Mesothelial cell Adventitial cell Pulmonary artery endothelial cell Respiratory tract suprabasal cell Naive b cell Endothelial cell of artery

Trachea Lower lobe of left lung Lung Bronchus Upper lobe of left lung

35-year-old stage Sixth decade stage 59-year-old stage 58-year-old stage 75-year-old stage 64-year-old stage 29-year-old stage 66-year-old stage Seventh decade stage

Normal

Female Male

10x 5' transcription profiling 10x 3' v3 10x 3' v2

Cell Nucleus

Mus musculus

Fibroblast Glial cell Smooth muscle cell Neutrophil B cell Pericyte Macrophage Sensory neuron of dorsal root ganglion Connective tissue cell Endothelial cell

Dorsal root ganglion

8-week-old stage 15-month-old stage

Peripheral neuropathy Normal

Female Male

10x multiome 10x 3' v3 Smart-seq3 Indrop Smart-seq2 10x 3' v2

Nucleus Cell

Homo sapiens

Mast cell Cardiac endothelial cell Lymphoid lineage restricted progenitor cell Cardiac muscle myoblast Neuronal receptor cell Adipocyte of epicardial fat of left ventricle Pericyte Immature innate lymphoid cell Smooth muscle myoblast Fibroblast of cardiac tissue

Heart left ventricle

74-year-old stage 61-year-old stage 57-year-old stage 52-year-old stage 40-year-old stage 38-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 51-year-old stage 64-year-old stage 66-year-old stage 63-year-old stage 60-year-old stage 43-year-old stage 44-year-old stage 47-year-old stage

Myocardial infarction Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast Lymph node macrophage Group 3 innate lymphoid cell, human Class switched memory b cell Mucosal invariant t cell Germinal center b cell Cd16-positive, cd56-dim natural killer cell, human Mast cell Dendritic cell, human Cd14-low, cd16-positive monocyte Granzyme k-associated cd8 t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Plasma cell Gamma-delta t cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Cd16-negative, cd56-bright natural killer cell, human Macrophage Marginal zone b cell of lymph node Double negative memory b cell Cd4-positive, alpha-beta memory t cell, cd45ro-positive Naive b cell Naive regulatory t cell T follicular helper cell Transitional stage b cell Cd14-positive, cd16-low monocyte

Axillary lymph node

35-year-old stage 27-year-old stage 19-year-old stage 21-year-old stage 40-year-old stage 38-year-old stage 41-year-old stage 22-year-old stage 50-year-old stage 32-year-old stage 24-year-old stage 34-year-old stage

Normal

Female Male

10x 5' v2

Cell

Homo sapiens

Sertoli cell Granulosa cell Mesenchymal cell Leydig cell Ovarian surface epithelial cell Supporting cell Interstitial cell of ovary Mesothelial cell

Gonad

Carnegie stage 19 21st week post-fertilization stage Carnegie stage 18 14th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 21 Carnegie stage 23 16th week post-fertilization stage 19th week post-fertilization stage 15th week post-fertilization stage 11th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 17 18th week post-fertilization stage 9th week post-fertilization stage 17th week post-fertilization stage

Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Mucosal invariant t cell Dendritic cell B cell Gamma-delta t cell Cd8-positive, alpha-beta t cell Natural killer cell Monocyte Cd4-positive, alpha-beta t cell T cell Stem cell

Blood

Sixth decade stage Fourth decade stage Fifth decade stage Seventh decade stage

Covid-19 Normal

Female Male

10x 5' v2 10x 5' v1

Cell

Homo sapiens

Fibroblast Retinal ganglion cell Retinal rod cell Schwann cell Myeloid cell Astrocyte Mast cell Amacrine cell Retina horizontal cell Mural cell Retinal bipolar neuron Melanocyte B cell Retinal pigment epithelial cell Muscle cell Retinal cone cell Mueller cell Mature nk t cell T cell Endothelial cell

Age-related macular degeneration Normal

Homo sapiens

Neuroblast (sensu vertebrata) Neuroblast (sensu nematoda and protostomia) Glioblast Oligodendrocyte Radial glial cell Neuron

Hypothalamus Diencephalon Dorsal plus ventral thalamus

Carnegie stage 20 15th week post-fertilization stage 9th week post-fertilization stage

Normal

10x 3' v3 10x 3' v2

Cell