Homo sapiens

Germinal center b cell Precursor b cell Memory b cell Plasmablast Plasma cell B cell Naive b cell

Lung Inguinal lymph node Jejunal epithelium Epithelial lining fluid Thoracic lymph node Spleen Jejunum lamina propria Blood Bone marrow Mesenteric lymph node

75-year-old stage Sixth decade stage 68-year-old stage 48-year-old stage 56-year-old stage Fifth decade stage Third decade stage 23-year-old stage 25-year-old stage 67-year-old stage 33-year-old stage 64-year-old stage Fourth decade stage 20-year-old stage Eighth decade stage 73-year-old stage 27-year-old stage

Normal

Female Male

10x 5' v2 10x 3' v3

Cell

Homo sapiens

Tracheobronchial smooth muscle cell Lung megakaryocyte Mature conventional dendritic cell Ciliated cell Natural killer cell Lung secretory cell Secretory cell Mast cell Lung interstitial macrophage Alveolar capillary type 1 endothelial cell Pulmonary neuroendocrine cell Serous secreting cell Basal cell Endothelial cell of respiratory system lymphatic vessel Endothelial cell of artery Classical monocyte Plasmacytoid dendritic cell Cd8-positive, alpha-beta cytotoxic t cell Goblet cell Brush cell of tracheobronchial tree Mesothelial cell of pleura Mucus secreting cell of tracheobronchial tree submucosal gland Regulatory t cell Pulmonary alveolar type 1 cell Helper t cell Alveolar macrophage Plasma cell Vein endothelial cell Secondary crest myofibroblast Alveolar adventitial fibroblast Vein endothelial cell of respiratory system B cell Alveolar capillary type 2 endothelial cell Pericyte Alveolar type 1 fibroblast cell Vascular associated smooth muscle cell Conventional dendritic cell Pulmonary alveolar type 2 cell Non-classical monocyte

Middle lobe of right lung

15-month-old stage 6-month-old stage 21-month-old stage 13-month-old stage 20-month-old stage 10-month-old stage 3-year-old stage 8-month-old stage 18-month-old stage 19-month-old stage 5-month-old stage 4-month-old stage 11-month-old stage 12-month-old stage 7-month-old stage 14-month-old stage

Normal Bronchopulmonary dysplasia

Female Male

10x 3' v3

Nucleus

Homo sapiens

Podocyte Natural killer cell Endothelial cell of lymphatic vessel Renal beta-intercalated cell Gamma-delta t cell Endothelial cell Mast cell Cd8-positive, alpha-beta t cell Iga plasma cell Effector memory cd4-positive, alpha-beta t cell Activated type ii nk t cell Classical monocyte Epithelial cell of proximal tubule Epithelial cell Plasmacytoid dendritic cell Igg plasma cell Epithelial cell of proximal tubule segment 1 Renal alpha-intercalated cell Naive thymus-derived cd8-positive, alpha-beta t cell Macrophage Unswitched memory b cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Kidney distal convoluted tubule epithelial cell Kidney pelvis urothelial cell Kidney collecting duct principal cell Innate lymphoid cell Kidney connecting tubule principal cell Kidney loop of henle thick ascending limb epithelial cell Mhc-ii-positive classical monocyte Epithelial cell of proximal tubule segment 3 Plasma cell Cd4-positive, alpha-beta t cell B cell Pericyte Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Collagen secreting cell Naive b cell Kidney loop of henle ascending limb epithelial cell Conventional dendritic cell Fibroblast Class switched memory b cell Effector memory cd8-positive, alpha-beta t cell Non-classical monocyte

Perirenal fat Vein Kidney Adrenal tissue Blood

Sixth decade stage Fifth decade stage Seventh decade stage Eighth decade stage

Kidney benign neoplasm Normal Nonpapillary renal cell carcinoma Kidney oncocytoma

Female Male

10x 5' transcription profiling

Cell

Homo sapiens

Gabaergic amacrine cell Retinal ganglion cell Retinal pigment epithelial cell Rod bipolar cell S cone cell Retinal bipolar neuron H2 horizontal cell Microglial cell Parasol ganglion cell of retina Retinal cone cell Glycinergic amacrine cell Retinal rod cell Amacrine cell Starburst amacrine cell Midget ganglion cell of retina Mueller cell Astrocyte H1 horizontal cell

Peripheral region of retina Macula lutea proper Fovea centralis Chorioretinal region Retinal neural layer

69-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 71-year-old stage 53-year-old stage 54-year-old stage 68-year-old stage 82-year-old stage 80-year-old stage 74-year-old stage Adult stage 64-year-old stage 86-year-old stage 60-year-old stage 78-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Central memory cd4-positive, alpha-beta t cell Germinal center b cell Stromal cell Natural killer cell Gastrointestinal tract (lamina propria) macrophage of large intestine Endothelial cell of lymphatic vessel Gamma-delta t cell Best4+ enterocyte Mast cell Stem cell Effector memory cd4-positive, alpha-beta t cell Endothelial cell of artery Capillary endothelial cell Paneth cell Enteroendocrine cell Goblet cell T-helper 17 cell Macrophage Tuft cell of colon Memory b cell Follicular b cell Innate lymphoid cell Regulatory t cell Glial cell Enterocyte Plasma cell Vein endothelial cell Transit amplifying cell T follicular helper cell B cell Pericyte T-helper 1 cell Monocyte Naive b cell Enterocyte of epithelium of large intestine Myofibroblast cell Conventional dendritic cell Effector memory cd8-positive, alpha-beta t cell

Transverse colon epithelium Colonic epithelium Duodenal mucosa Jejunal mucosa Lamina propria of mucosa of colon Transverse colon lamina propria Mucosa of ascending colon Caecum lamina propria Mucosa of transverse colon Cecum mucosa Ileal mucosa Mucosa of appendix Caecum epithelium Mucosa of descending colon Mucosa of sigmoid colon Mucosa of rectum

Sixth decade stage 53-year-old stage 29-year-old stage Fifth decade stage Third decade stage Seventh decade stage Adult stage 45-year-old stage Eighth decade stage

Normal

Female Male

10x 3' v1 10x 5' v2 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Central memory cd4-positive, alpha-beta t cell T cell Basophilic erythroblast Cd14-positive, cd16-positive monocyte Natural killer cell Erythroid progenitor cell Small pre-b-ii cell Stromal cell of bone marrow Pro-b cell Late pro-b cell Effector memory cd4-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Pre-conventional dendritic cell Basophil mast progenitor cell Megakaryocyte progenitor cell Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Large pre-b-ii cell Mature b cell Promonocyte Polychromatophilic erythroblast Hematopoietic stem cell Common myeloid progenitor Plasma cell Cd14-positive monocyte Hematopoietic multipotent progenitor cell Megakaryocyte Hematopoietic oligopotent progenitor cell Orthochromatic erythroblast Granulocyte monocyte progenitor cell Naive thymus-derived cd4-positive, alpha-beta t cell Common lymphoid progenitor Immature b cell Megakaryocyte-erythroid progenitor cell Central memory cd8-positive, alpha-beta t cell Conventional dendritic cell Dendritic cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell

Bone marrow

66-year-old stage 26-year-old stage 43-year-old stage 52-year-old stage 30-year-old stage 39-year-old stage 29-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 50-year-old stage 28-year-old stage 57-year-old stage 24-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage Late adult stage 32-year-old stage 41-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage 36-year-old stage 19-year-old stage 47-year-old stage Prime adult stage Young adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Mus musculus

T cell Neutrophil Hepatocyte Endothelial cell Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Hepatic portal fibroblast Cholangiocyte B cell

Normal

10x 3' v3

Homo sapiens

Cycling t cell Gamma-delta t cell Cd8-positive, alpha-beta memory t cell Group 3 innate lymphoid cell Naive thymus-derived cd8-positive, alpha-beta t cell T-helper 17 cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell T follicular helper cell Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell

Ascending colon Colonic mucosa Stomach Duodenum Colonic epithelium Ileal epithelium Rectosigmoid junction Pyloric antrum Caecum Small intestine Gingiva Ileum Ileum lamina propria Lamina propria of mucosa of colon Colon Epithelium of rectum Lamina propria of small intestine Epithelium of esophagus Intestine Buccal mucosa Body of stomach Vermiform appendix Epithelium of small intestine Pylorus Rectum Esophagus Jejunum Duodenal epithelium Transverse colon Periodontium Parotid gland Descending colon Sigmoid colon Labial gland Epithelium of stomach Mesenteric lymph node

66-year-old stage 69-year-old stage Carnegie stage 19 37-year-old stage 75-year-old stage Pediatric stage 19th week post-fertilization stage 21-year-old stage 13-year-old stage 21st week post-fertilization stage 34-year-old stage 65-year-old stage 26-year-old stage 43-year-old stage Sixth decade stage 87-year-old stage 13th week post-fertilization stage 85-year-old stage 61-year-old stage 2-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 29-year-old stage 56-year-old stage Fifth decade stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 50-year-old stage 80-year-old stage 28-year-old stage 51-year-old stage 17th week post-fertilization stage 57-year-old stage 12-year-old stage 72-year-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 81-year-old stage 9th week post-fertilization stage 74-year-old stage 9-year-old stage 10th week post-fertilization stage 14-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage Seventh decade stage 58-year-old stage 59-year-old stage Adult stage 67-year-old stage 18th week post-fertilization stage Carnegie stage 17 2-month-old stage 32-year-old stage 77-year-old stage 33-year-old stage Carnegie stage 22 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage Fourth decade stage 22-year-old stage Newborn stage (0-28 days) 63-year-old stage Eighth decade stage 76-year-old stage Prime adult stage 5-year-old stage 11-year-old stage 6-year-old stage Young adult stage 10-year-old stage 4-year-old stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Gastric cancer Inflammatory bowel disease Colorectal cancer Ulcerative colitis Normal Crohn disease

Female Male

10x 3' v1 10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Malignant cell

Scrotum Prostate gland

Pediatric stage

Rhabdomyosarcoma

Male

10x 5' transcription profiling

Cell

Mus musculus

Granulocyte Central nervous system macrophage Kupffer cell Adipose macrophage Plasmacytoid dendritic cell Microglial cell Hematopoietic stem cell Myeloid suppressor cell Monocyte Conventional dendritic cell Osteoclast

Embryo

Theiler stage 22 Theiler stage 27 Theiler stage 24 Theiler stage 18 Theiler stage 25 Theiler stage 14 Theiler stage 16 Theiler stage 17 Theiler stage 15 Theiler stage 19 Theiler stage 26 Theiler stage 13 Theiler stage 20 Theiler stage 12 Theiler stage 21 Theiler stage 23

Normal

Female Male

Sci-rna-seq3

Nucleus

Callithrix jacchus

Oligodendrocyte

Brodmann (1909) area 25 Lateral amygdaloid nucleus Dorsolateral prefrontal cortex Thalamic complex Parietal cortex Medial dorsal nucleus of thalamus Primary visual cortex Ventral lateral nucleus of thalamus Brainstem Temporal cortex Lateral nuclear group of thalamus Caudate nucleus Prefrontal cortex Anterior hypothalamic region Temporal lobe Central amygdaloid nucleus Cerebellum lobule Nucleus accumbens Ventral thalamus Basal forebrain Primary somatosensory cortex Primary auditory cortex Brodmann (1909) area 23 Primary motor cortex Dorsal thalamus Hippocampal formation Secondary visual cortex Posterior hypothalamic region Lateral geniculate body Putamen Medial amygdaloid nucleus Amygdala

Late adult stage Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Neutrophil Periportal region hepatocyte Dendritic cell, human Endothelial cell of periportal hepatic sinusoid Natural killer cell Centrilobular region hepatocyte Midzonal region hepatocyte Inflammatory macrophage Leukocyte Classical monocyte Plasmacytoid dendritic cell Hepatic stellate cell Macrophage Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Endothelial cell of pericentral hepatic sinusoid Cd16-positive, cd56-dim natural killer cell, human Cholangiocyte Plasma cell Cd4-positive, alpha-beta t cell B cell Mucosal invariant t cell Conventional dendritic cell Fibroblast Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Non-classical monocyte

Caudate lobe of liver Liver

66-year-old stage 69-year-old stage 75-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 26-year-old stage 53-year-old stage 52-year-old stage 68-year-old stage 44-year-old stage 55-year-old stage 28-year-old stage 72-year-old stage 49-year-old stage 58-year-old stage Adult stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 73-year-old stage Prime adult stage Young adult stage

Normal

Female Male

10x 3' v3 Cel-seq2 10x 3' v2

Nucleus Cell