Homo sapiens

Fibroblast

Breast

Adult stage Prime adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Innate lymphoid cell Plasmablast Mucosal invariant t cell Cd14-low, cd16-positive monocyte Cd4-positive, alpha-beta cytotoxic t cell Hematopoietic precursor cell Cd4-positive, alpha-beta memory t cell Cd141-positive myeloid dendritic cell Memory b cell Cd14-positive, cd16-negative classical monocyte Dendritic cell Gamma-delta t cell Regulatory t cell Cd1c-positive myeloid dendritic cell Naive thymus-derived cd4-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Erythroid lineage cell Activated cd8-positive, alpha-beta t cell Effector cd4-positive, alpha-beta t cell Cd16-negative, cd56-bright natural killer cell, human Natural killer cell Mature b cell Platelet Cd4-negative, cd8-negative, alpha-beta intraepithelial t cell Cd8-positive, alpha-beta memory t cell Naive b cell

Blood

74-year-old stage 82-year-old stage 58-year-old stage 77-year-old stage 69-year-old stage 63-year-old stage 67-year-old stage

Open-angle glaucoma Normal

Female Male

10x 5' v2

Cell

Mus musculus

L6b glutamatergic cortical neuron Astrocyte Lamp5 gabaergic interneuron L6 intratelencephalic projecting glutamatergic neuron L4/5 intratelencephalic projecting glutamatergic neuron Smooth muscle cell L2/3 intratelencephalic projecting glutamatergic neuron Vip gabaergic interneuron Oligodendrocyte precursor cell Oligodendrocyte L6 corticothalamic-projecting glutamatergic cortical neuron L5 intratelencephalic projecting glutamatergic neuron Pericyte L5/6 near-projecting glutamatergic neuron Pvalb gabaergic interneuron Sncg gabaergic interneuron Sst gabaergic interneuron Perivascular macrophage L5 extratelencephalic projecting glutamatergic cortical neuron Vascular leptomeningeal cell Microglial cell Endothelial cell

Cerebral cortex

Prime adult stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Myeloid cell Mast cell Cardiac endothelial cell Mural cell Cardiac muscle cell Lymphocyte Adipocyte Cardiac neuron Fibroblast of cardiac tissue

Heart left ventricle Apex of heart

27-year-old stage 26-year-old stage 19-year-old stage Third decade stage 21-year-old stage 61-year-old stage Sixth decade stage 49-year-old stage 52-year-old stage 70-year-old stage 38-year-old stage Eighth decade stage 30-year-old stage 55-year-old stage 64-year-old stage 29-year-old stage 32-year-old stage 28-year-old stage Fifth decade stage 31-year-old stage 25-year-old stage 24-year-old stage Seventh decade stage

Myocarditis Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Fibroblast Schwann cell Neuroblast (sensu vertebrata)

Adrenal gland Neck Liver Chest Abdomen Cervical lymph node Lymph node

12-month-old stage 13-year-old stage 18-month-old stage 7-year-old stage 4-year-old stage 12-year-old stage 3-year-old stage 2-year-old stage 15-month-old stage 5-year-old stage 20-month-old stage 6-month-old stage 21-month-old stage 16-month-old stage

Neuroblastoma

Female Male

10x 3' v3

Nucleus

Mus musculus

Fibroblast Epithelial cell of proximal tubule segment 3 Urothelial cell Kidney loop of henle descending limb epithelial cell Kidney loop of henle ascending limb epithelial cell Parietal epithelial cell Epithelial cell of proximal tubule Podocyte Kidney connecting tubule epithelial cell Ureteric bud cell Plasma cell Epithelial cell of proximal tubule segment 1 Metanephric nephron tubule epithelial cell Kidney distal convoluted tubule epithelial cell Macrophage Kidney collecting duct intercalated cell Conventional dendritic cell Kidney collecting duct principal cell Epithelial cell of proximal tubule segment 2 T cell Endothelial cell

Kidney

12-month-old stage Theiler stage 24 21-month-old stage 21-day-old stage Theiler stage 27 3-6 month-old mature stage

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Fibroblast Secondary lymphoid organ macrophage Slow muscle cell Mast cell Vein endothelial cell Mesenchymal stem cell Mural cell Capillary endothelial cell Pericyte Skeletal muscle satellite stem cell Erythroid lineage cell Lymphocyte Adipocyte Cell of skeletal muscle Endothelial cell of lymphatic vessel Tendon cell Macrophage Fast muscle cell Endothelial cell of artery

Skeletal muscle organ, vertebrate Muscle of abdomen Muscle of pelvic diaphragm Rectus abdominis muscle Muscle tissue

54-year-old stage 90-year-old stage Adult stage 62-year-old stage 74-year-old stage 72-year-old stage 19-year-old stage 21-year-old stage 81-year-old stage 61-year-old stage 82-year-old stage 70-year-old stage 38-year-old stage 59-year-old stage 75-year-old stage 22-year-old stage 79-year-old stage 77-year-old stage 76-year-old stage 43-year-old stage 20-year-old stage 71-year-old stage

Normal

Female Male

10x 5' transcription profiling 10x 3' v3 Smart-seq2 10x 5' v1 10x 3' v2

Cell Nucleus

Homo sapiens

Innate lymphoid cell Mast cell Naive t cell Neutrophil Plasma cell Dendritic cell B cell Regulatory t cell Intraepithelial lymphocyte Plasmacytoid dendritic cell Cd8-positive, alpha-beta t cell Natural killer cell Macrophage Conventional dendritic cell Monocyte Cd4-positive, alpha-beta t cell T cell

Ileum lamina propria Ileal epithelium Ileum Small intestine Epithelium of small intestine Lamina propria of small intestine

Third decade stage Sixth decade stage Fourth decade stage Eighth decade stage Fifth decade stage Seventh decade stage

Crohn disease Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Innate lymphoid cell Plasmablast Effector memory cd4-positive, alpha-beta t cell Mucosal invariant t cell Hematopoietic multipotent progenitor cell Cd16-positive, cd56-dim natural killer cell, human Mast cell Effector memory cd8-positive, alpha-beta t cell Dendritic cell, human Central memory cd4-positive, alpha-beta t cell Neutrophil Memory b cell Plasma cell B cell Gamma-delta t cell Regulatory t cell Megakaryocyte Non-classical monocyte Plasmacytoid dendritic cell Erythroid lineage cell Leukocyte Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Cd16-negative, cd56-bright natural killer cell, human Central memory cd8-positive, alpha-beta t cell Macrophage Erythrocyte Conventional dendritic cell Classical monocyte Naive b cell T follicular helper cell Endothelial cell

Spleen

Third decade stage 61-year-old stage Sixth decade stage 59-year-old stage Eighth decade stage 69-year-old stage Fifth decade stage 31-year-old stage Seventh decade stage

Normal

Female Male

10x 5' transcription profiling 10x 3' v3 10x 5' v2 Smart-seq2 10x 5' v1 10x 3' v2

Cell

Mus musculus

Innate lymphoid cell Perivascular cell Schwann cell Mast cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Neutrophil Mammary gland epithelial cell Plasma cell B cell Blood vessel endothelial cell Lactocyte Myeloid leukocyte Plasmacytoid dendritic cell Migratory dendritic cell Cd8-positive, alpha-beta t cell Natural killer cell Macrophage Fibroblast of mammary gland Luminal hormone-sensing cell of mammary gland Conventional dendritic cell Basal-myoepithelial cell of mammary gland Luminal adaptive secretory precursor cell of mammary gland Cd4-positive, alpha-beta t cell Cycling t cell

Mammary gland

12-month-old stage 10-month-old stage 13-month-old stage 9-month-old stage 7-month-old stage 11-month-old stage 8-month-old stage 3-month-old stage 18-month-old stage

Neoplasm Normal

Female

10x 3' v3 10x 3' v2

Cell

Mus musculus

Mast cell Smooth muscle cell Neutrophil Epithelial cell Mammary gland epithelial cell Dendritic cell B cell Pericyte Adipocyte Endothelial cell of lymphatic vessel Macrophage Monocyte Mature nk t cell Preadipocyte Mesothelial cell T cell Endothelial cell

Periovarian fat pad Epididymal fat pad Inguinal fat pad

19-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast Astrocyte Mast cell Oligodendrocyte precursor cell Oligodendrocyte B cell Pericyte Interneuron Ependymal cell Macrophage Microglial cell Choroid plexus epithelial cell T cell Neuron Endothelial cell

Normal Alzheimer disease

10x 3' v3