Homo sapiens

Natural killer cell Cd8-positive, alpha-beta t cell Monocyte Gamma-delta t cell Dendritic cell T cell Stem cell Mucosal invariant t cell Cd4-positive, alpha-beta t cell B cell

Blood

Fifth decade stage Fourth decade stage Seventh decade stage Sixth decade stage

Normal Covid-19

Female Male

10x 5' v2 10x 5' v1

Cell

Homo sapiens

Mature nk t cell Retinal bipolar neuron Retinal cone cell Schwann cell Mast cell Fibroblast Mural cell Amacrine cell Mueller cell T cell Retinal ganglion cell Retinal pigment epithelial cell Myeloid cell Muscle cell Endothelial cell Retinal rod cell B cell Melanocyte Astrocyte Retina horizontal cell

Normal Age-related macular degeneration

Homo sapiens

Oligodendrocyte Neuroblast (sensu vertebrata) Neuron Glioblast Radial glial cell Neuroblast (sensu nematoda and protostomia)

Dorsal plus ventral thalamus Hypothalamus Diencephalon

15th week post-fertilization stage 9th week post-fertilization stage Carnegie stage 20

Normal

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Sst gabaergic interneuron Pvalb gabaergic interneuron Pvalb chandelier gabaergic interneuron

Angular gyrus Anterior cingulate cortex Primary motor cortex Primary visual cortex Middle temporal gyrus Primary auditory cortex Primary somatosensory cortex Dorsolateral prefrontal cortex

50-year-old stage 43-year-old stage 29-year-old stage 42-year-old stage 60-year-old stage Sixth decade stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Cd8-positive, alpha-beta t cell

T cell

Fifth decade stage Ninth decade stage Eighth decade stage Fourth decade stage Seventh decade stage Sixth decade stage Third decade stage

B-cell non-hodgkin lymphoma

Female Male

10x 5' v1

Cell

Homo sapiens

Natural killer cell Endothelial cell of arteriole Erythrocyte Naive b cell Cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Fibroblast of the aortic adventitia Capillary endothelial cell Mast cell Fibroblast Mural cell Pericyte Tendon cell Myelinating schwann cell Perineurial cell Memory b cell Type ii muscle cell Mature neutrophil Macrophage Type i muscle cell T cell Cd14-low, cd16-positive monocyte Mesothelial cell Non-myelinating schwann cell Vein endothelial cell Naive t cell Cd16-negative, cd56-bright natural killer cell, human Eosinophil Adipocyte Blood vessel endothelial cell Conventional dendritic cell Plasma cell Immature neutrophil Cd4-positive, cd25-positive, alpha-beta regulatory t cell Muscle cell Plasmacytoid dendritic cell Cd4-positive, alpha-beta t cell Cd16-positive, cd56-dim natural killer cell, human Smooth muscle cell Endothelial cell of artery B cell Cd14-positive, cd16-low monocyte Skeletal muscle satellite stem cell

Intercostal muscle

Eighth decade stage Fourth decade stage Seventh decade stage Young adult stage Sixth decade stage Third decade stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell Nucleus

Homo sapiens

Mature nk t cell Natural killer cell Mature conventional dendritic cell Cd8-positive, alpha-beta t cell Monocyte Igg plasma cell Group 3 innate lymphoid cell T-helper 17 cell Activated cd4-positive, alpha-beta t cell Macrophage Gamma-delta t cell Dendritic cell T cell Cd8-positive, alpha-beta memory t cell Mature b cell Granulocyte Conventional dendritic cell Germinal center b cell Iga plasma cell Cd4-positive, cd25-positive, alpha-beta regulatory t cell Plasmacytoid dendritic cell Cd4-positive, alpha-beta t cell T follicular helper cell Effector cd8-positive, alpha-beta t cell

Colorectum

64-year-old stage 91-year-old stage 50-year-old stage 52-year-old stage 82-year-old stage 35-year-old stage 58-year-old stage 73-year-old stage 84-year-old stage 42-year-old stage 49-year-old stage 59-year-old stage 61-year-old stage 57-year-old stage 89-year-old stage 53-year-old stage 56-year-old stage 55-year-old stage 77-year-old stage 78-year-old stage 47-year-old stage 36-year-old stage 45-year-old stage 70-year-old stage 81-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 90-year-old stage 60-year-old stage 62-year-old stage 72-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage

Normal Colon adenocarcinoma

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Natural killer cell Endothelial cell of arteriole Mast cell Fibroblast Monocyte Pericyte Myelinating schwann cell Macrophage Dendritic cell T cell Non-myelinating schwann cell Retinal pigment epithelial cell Endothelial cell of venule Blood vessel smooth muscle cell Plasma cell Fenestrated endothelial cell B cell Melanocyte

Eyeball of camera-type eye Optic choroid Chorioretinal region Pigmented layer of retina

24th week post-fertilization stage 80 year-old and over stage 80-year-old stage 64-year-old stage 15th week post-fertilization stage 52-year-old stage 82-year-old stage 43-year-old stage 41-year-old stage 63-year-old stage 11th week post-fertilization stage 21st week post-fertilization stage 75-year-old stage 84-year-old stage 22nd week post-fertilization stage 1-month-old stage 86-year-old stage 54-year-old stage 13th week post-fertilization stage 61-year-old stage 11-year-old stage 19th week post-fertilization stage 83-year-old stage 89-year-old stage 77-year-old stage 78-year-old stage 12th week post-fertilization stage 10th week post-fertilization stage 81-year-old stage 76-year-old stage 6-month-old stage 40-year-old stage 88-year-old stage Newborn stage (0-28 days) 17th week post-fertilization stage 16th week post-fertilization stage 39-year-old stage 27th week post-fertilization stage 79-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3 10x 5' v2

Cell

Homo sapiens

Oligodendrocyte Immature astrocyte Unipolar brush cell Cerebellar granule cell precursor Interneuron Neuroblast (sensu vertebrata) Leukocyte Progenitor cell Noradrenergic cell Meningeal macrophage Purkinje cell Committed oligodendrocyte precursor T cell Central nervous system macrophage Erythroid lineage cell Oligodendrocyte precursor cell Cerebellar granule cell Microglial cell Brain vascular cell Gabaergic neuron Macroglial cell Glioblast Bergmann glial cell Glutamatergic neuron

Cerebellum vermis lobule Hemisphere part of cerebellar posterior lobe Dentate nucleus Cerebellum Cerebellar cortex

52-year-old stage 11th week post-fertilization stage 3-year-old stage 42-year-old stage Carnegie stage 18 9th week post-fertilization stage Carnegie stage 22 46-year-old stage 44-year-old stage 7-month-old stage 6-month-old stage Newborn stage (0-28 days) 17th week post-fertilization stage Carnegie stage 19 20th week post-fertilization stage 9-month-old stage

Normal Congenital heart disease Acute myocardial infarction Heart failure

Female Male

10x 3' v2 10x 3' v3

Nucleus

Homo sapiens

Megakaryocyte Endothelial cell of lymphatic vessel Mast cell Vascular associated smooth muscle cell Cardiac neuron Pericyte Cardiac atrium fibroblast Macrophage T cell Mesothelial cell Adipocyte Cardiac muscle cell Cardiac endothelial cell B cell

Normal Atrial fibrillation

10x 3' v3

Homo sapiens

Oligodendrocyte

Substantia nigra pars compacta

91-year-old stage 82-year-old stage 75-year-old stage 49-year-old stage 92-year-old stage 74-year-old stage 83-year-old stage 89-year-old stage 78-year-old stage 70-year-old stage 76-year-old stage 90-year-old stage 79-year-old stage

Normal Lewy body dementia Parkinson disease

Female Male

10x 3' v3

Nucleus

Homo sapiens

Direct pathway medium spiny neuron Sst gabaergic interneuron Purkinje cell Indirect pathway medium spiny neuron Lamp5 gabaergic interneuron Pvalb gabaergic interneuron Thalamic excitatory neuron Central nervous system neuron Cerebellar neuron Sncg gabaergic interneuron Pvalb chandelier gabaergic interneuron Vip gabaergic interneuron

Hippocampal formation Agranular insular cortex Brodmann (1909) area 24 Medial dorsal nucleus of thalamus Body of caudate nucleus Insula Posterior parahippocampal gyrus Granular insular cortex Substantia innominata Hippocampal field Central nucleus of inferior colliculus Central amygdaloid nucleus Corticomedial nuclear complex Bed nucleus of stria terminalis Lateral entorhinal cortex Brodmann (1909) area 19 Brodmann (1909) area 38 Anterior cingulate cortex Brodmann (1909) area 46 Primary motor cortex Claustrum of brain Inferior temporal gyrus Primary visual cortex Cuneus cortex Pontine nuclear group Middle temporal gyrus Subiculum Parietal cortex Secondary visual cortex Septal nuclear complex Primary auditory cortex Piriform cortex Primary somatosensory cortex Medial entorhinal cortex Globus pallidus Basolateral amygdaloid nuclear complex Brodmann (1909) area 25 Cerebellum Amygdala Prefrontal cortex Nucleus accumbens Pulvinar nucleus Dentate gyrus of hippocampal formation Putamen

29-year-old stage 58-year-old stage 42-year-old stage

Normal

Male

Snmc-seq2

Nucleus