Homo sapiens

Innate lymphoid cell Double negative thymocyte Common myeloid progenitor Hematopoietic multipotent progenitor cell Group 2 innate lymphoid cell Early lymphoid progenitor Fraction a pre-pro b cell Regulatory t cell Megakaryocyte Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Hematopoietic stem cell Promonocyte Megakaryocyte-erythroid progenitor cell Granulocyte monocyte progenitor cell Natural killer cell Cd8-alpha-alpha-positive, alpha-beta intraepithelial t cell Group 3 innate lymphoid cell T cell Double-positive, alpha-beta thymocyte

Skin of body Mesenteric lymph node Liver Gut wall Bone marrow Kidney Spleen Yolk sac Thymus

Carnegie stage 19 Carnegie stage 20 14th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 23 16th week post-fertilization stage Carnegie stage 22 Carnegie stage 13 15th week post-fertilization stage 11th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage 17th week post-fertilization stage

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

L6b glutamatergic cortical neuron Myeloid cell Astrocyte Lamp5 gabaergic interneuron Inhibitory interneuron Pvalb chandelier gabaergic interneuron Smooth muscle cell L2/3 intratelencephalic projecting glutamatergic neuron Vip gabaergic interneuron Oligodendrocyte precursor cell Oligodendrocyte B cell L6 corticothalamic-projecting glutamatergic cortical neuron Pericyte Erythroid lineage cell L5/6 near-projecting glutamatergic neuron of the primary motor cortex Pvalb gabaergic interneuron Macrophage Sst gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Vascular leptomeningeal cell Microglial cell T cell Endothelial cell

Dorsolateral prefrontal cortex

19-year-old stage 36-year-old stage 50-year-old stage 64-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Mural cell

Heart left ventricle Apex of heart Interventricular septum Heart right ventricle

Third decade stage Postnatal stage Sixth decade stage Fourth decade stage Eighth decade stage Fifth decade stage Pediatric stage Seventh decade stage

Non-compaction cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Middle temporal gyrus

Adult stage 78-year-old stage 80 year-old and over stage 72-year-old stage 83-year-old stage 85-year-old stage 81-year-old stage 82-year-old stage 86-year-old stage 70-year-old stage 75-year-old stage 50-year-old stage 89-year-old stage 68-year-old stage 29-year-old stage 77-year-old stage 69-year-old stage 88-year-old stage 87-year-old stage 60-year-old stage 80-year-old stage 84-year-old stage 43-year-old stage 65-year-old stage

Dementia Normal

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Enteroendocrine cell Enterocyte Colon goblet cell Goblet cell Glandular secretory epithelial cell Tuft cell of colon Colonocyte Intestinal epithelial cell Stem cell

Colorectum

90-year-old stage 35-year-old stage 62-year-old stage 78-year-old stage 73-year-old stage 72-year-old stage 53-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage 82-year-old stage 49-year-old stage 42-year-old stage 36-year-old stage 52-year-old stage 48-year-old stage 70-year-old stage 45-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 50-year-old stage 51-year-old stage 89-year-old stage 64-year-old stage 77-year-old stage 69-year-old stage 76-year-old stage 60-year-old stage 84-year-old stage 56-year-old stage 91-year-old stage 67-year-old stage 71-year-old stage 47-year-old stage

Colon adenocarcinoma Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Fibroblast Fibro/adipogenic progenitor cell Innate lymphoid cell Perivascular cell Memory t cell Mast cell Decidual cell Stromal cell of endometrium Hematopoietic precursor cell Epithelial cell Stromal cell Cd4-positive, alpha-beta memory t cell Uterine smooth muscle cell B cell Regulatory t cell Blood vessel endothelial cell Luminal endometrial multiciliated epithelial cell Circulating fibrocyte Myoepithelial cell Capillary endothelial cell Endothelial cell of uterus Glandular secretory epithelial cell Leukocyte Endothelial cell of venule Endothelial cell of lymphatic vessel Natural killer cell Macrophage Ciliated epithelial cell Cd8-positive, alpha-beta memory t cell Endothelial cell of artery

Myometrium Endometrium

26-year-old stage 23-year-old stage 29-year-old stage 32-year-old stage 28-year-old stage Young adult stage 31-year-old stage 37-year-old stage

Normal

Female

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Kupffer cell Alveolar macrophage Mature conventional dendritic cell Non-classical monocyte Apoptosis fated cell Macrophage Conventional dendritic cell Monocyte Classical monocyte

Pulmonary systemic sclerosis Pulmonary fibrosis Primary biliary cholangitis Hepatocellular carcinoma Metabolic dysfunction-associated steatohepatitis Alcoholic liver cirrhosis Normal

10x 3' v3 10x 3' v2

Homo sapiens

Fibroblast Cholangiocyte Basophil Neutrophil Plasma cell B cell Hepatocyte Plasmacytoid dendritic cell Natural killer cell Macrophage Conventional dendritic cell Monocyte T cell Endothelial cell

Liver

Adult stage 73-year-old stage 72-year-old stage 53-year-old stage 49-year-old stage 55-year-old stage 58-year-old stage 75-year-old stage 64-year-old stage 68-year-old stage 66-year-old stage 77-year-old stage 33-year-old stage 28-year-old stage 46-year-old stage 67-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Cd14-positive, cd16-positive monocyte Mast cell Dendritic cell, human Cd14-positive monocyte Naive t cell Activated cd4-positive, alpha-beta t cell, human B cell Regulatory t cell Megakaryocyte Myofibroblast cell Naive thymus-derived cd8-positive, alpha-beta t cell Abnormal cell Effector cd4-positive, alpha-beta t cell Conventional dendritic cell Mature nk t cell Cd4-positive, alpha-beta t cell Endothelial cell

Blood Kidney Lymph node

54-year-old stage 57-year-old stage 50-year-old stage 64-year-old stage 69-year-old stage 63-year-old stage

Clear cell renal carcinoma

Female Male

10x 5' v2

Cell

Mus musculus

Gabaergic neuron

Primary motor cortex Dentate gyrus of hippocampal formation Nucleus accumbens Primary somatosensory cortex Lateral septal complex Cerebral cortex Piriform cortex Anterior olfactory nucleus Pallidum Anterior cerebral artery Primary auditory cortex Olfactory cortex Secondary somatosensory cortex Caudate-putamen Hippocampal field Orbitofrontal cortex

Prime adult stage

Normal

Male

Scatac-seq

Nucleus

Homo sapiens

Mast cell Dendritic cell Monocyte

Abdominal wall Paracolic gutter Transverse colon Parietal peritoneum Caecum Liver Adnexa of uterus Ascitic fluid Right ovary Peritoneum Large intestine Omentum Urinary bladder Left ovary Abdomen Intestine Diaphragm Fallopian tube Lymph node

78-year-old stage 80 year-old and over stage 61-year-old stage 57-year-old stage 70-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 75-year-old stage 50-year-old stage 64-year-old stage 68-year-old stage 66-year-old stage 77-year-old stage 69-year-old stage 76-year-old stage 63-year-old stage 60-year-old stage 56-year-old stage 46-year-old stage 71-year-old stage 47-year-old stage

Malignant ovarian serous tumor

Female

10x 3' v3

Cell

Homo sapiens

Serotonergic neuron Schwann cell Neural progenitor cell Dopaminergic neuron Neuroblast (sensu vertebrata) Gabaergic neuron Glycinergic neuron Neuroblast (sensu nematoda and protostomia) Committed oligodendrocyte precursor Glioblast Oligodendrocyte precursor cell Oligodendrocyte Purkinje cell Vascular associated smooth muscle cell Pericyte Interneuron Leukocyte Progenitor cell Glutamatergic neuron Sensory neuron of dorsal root ganglion Radial glial cell Perivascular macrophage Vascular leptomeningeal cell Microglial cell Neuron Immature t cell Endothelial cell

Midbrain Brain Pons Cerebellum Telencephalon Diencephalon Hindbrain Medulla oblongata

10th week post-fertilization stage Embryonic stage 13th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage

Normal

Female Male

10x multiome

Nucleus