Homo sapiens

Mast cell Stromal cell of endometrium Smooth muscle cell Neutrophil Dendritic cell B cell Pericyte Adipocyte Endothelial cell of lymphatic vessel Macrophage Monocyte Preadipocyte Mesothelial cell T cell Immature nk t cell Endothelial cell

Subcutaneous adipose tissue Omental fat pad

54-year-old stage 35-year-old stage 73-year-old stage 53-year-old stage 57-year-old stage 49-year-old stage 36-year-old stage 41-year-old stage 59-year-old stage 58-year-old stage 51-year-old stage 68-year-old stage 29-year-old stage 24-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v3 Drop-seq

Nucleus Cell

Homo sapiens

Fibroblast Schwann cell Neural progenitor cell Endodermal cell Epidermal cell Epithelial cell Splanchnic mesodermal cell Primordial germ cell Blood cell Intermediate mesodermal cell Sensory neuron Mesodermal cell Lateral mesodermal cell Somatic stem cell Neuron Paraxial cell Endothelial cell

Embryoid body

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Cd4-positive, alpha-beta t cell

T cell

Ninth decade stage Third decade stage Sixth decade stage Fourth decade stage Eighth decade stage Fifth decade stage Seventh decade stage

B-cell non-hodgkin lymphoma

Female Male

10x 5' v1

Cell

Homo sapiens

L6b glutamatergic cortical neuron Amygdala excitatory neuron L2/3-6 intratelencephalic projecting glutamatergic neuron L6 corticothalamic-projecting glutamatergic cortical neuron Hippocampal neuron Hippocampal ca1-3 neuron Dentate gyrus neuron L5 extratelencephalic projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron

Primary motor cortex Inferior temporal gyrus Dentate gyrus of hippocampal formation Primary visual cortex Brodmann (1909) area 46 Globus pallidus Nucleus accumbens Primary somatosensory cortex Central nucleus of inferior colliculus Subiculum Insula Cuneus cortex Medial dorsal nucleus of thalamus Putamen Brodmann (1909) area 25 Amygdala Corticomedial nuclear complex Brodmann (1909) area 19 Piriform cortex Granular insular cortex Secondary visual cortex Primary auditory cortex Brodmann (1909) area 24 Lateral entorhinal cortex Septal nuclear complex Basolateral amygdaloid nuclear complex Middle temporal gyrus Brodmann (1909) area 38 Agranular insular cortex Pulvinar nucleus Body of caudate nucleus Hippocampal formation Anterior cingulate cortex Medial entorhinal cortex Prefrontal cortex Parietal cortex Posterior parahippocampal gyrus Pontine nuclear group Substantia innominata Bed nucleus of stria terminalis Central amygdaloid nucleus Hippocampal field Claustrum of brain

42-year-old stage 58-year-old stage 29-year-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

L6b glutamatergic cortical neuron Amygdala excitatory neuron L2/3-6 intratelencephalic projecting glutamatergic neuron L6 corticothalamic-projecting glutamatergic cortical neuron Hippocampal neuron Hippocampal ca1-3 neuron Dentate gyrus neuron L5 extratelencephalic projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron

Primary motor cortex Inferior temporal gyrus Dentate gyrus of hippocampal formation Primary visual cortex Brodmann (1909) area 46 Globus pallidus Nucleus accumbens Primary somatosensory cortex Central nucleus of inferior colliculus Subiculum Insula Cuneus cortex Medial dorsal nucleus of thalamus Putamen Brodmann (1909) area 25 Amygdala Corticomedial nuclear complex Brodmann (1909) area 19 Piriform cortex Granular insular cortex Secondary visual cortex Primary auditory cortex Brodmann (1909) area 24 Lateral entorhinal cortex Septal nuclear complex Basolateral amygdaloid nuclear complex Middle temporal gyrus Brodmann (1909) area 38 Agranular insular cortex Pulvinar nucleus Body of caudate nucleus Hippocampal formation Anterior cingulate cortex Medial entorhinal cortex Prefrontal cortex Parietal cortex Posterior parahippocampal gyrus Pontine nuclear group Substantia innominata Bed nucleus of stria terminalis Central amygdaloid nucleus Hippocampal field Claustrum of brain

42-year-old stage 58-year-old stage 29-year-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

Neural progenitor cell Neuron

Forebrain

Carnegie stage 01

Normal

Female Male

10x 3' v3

Cell

Macaca mulatta

Mast cell Neutrophil Epithelial cell B cell Eosinophil Macrophage T cell

Disease

Seq-well

Homo sapiens

Innate lymphoid cell Plasmablast Effector memory cd4-positive, alpha-beta t cell Double negative thymocyte Mucosal invariant t cell Effector memory cd8-positive, alpha-beta t cell Cd14-low, cd16-positive monocyte Cd14-positive monocyte Cd4-positive, alpha-beta cytotoxic t cell Central memory cd4-positive, alpha-beta t cell Memory b cell B cell Gamma-delta t cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Hematopoietic stem cell Plasmacytoid dendritic cell Memory regulatory t cell Cd8-positive, alpha-beta t cell Cd16-negative, cd56-bright natural killer cell, human Central memory cd8-positive, alpha-beta t cell Natural killer cell Platelet Erythrocyte Conventional dendritic cell Cd4-positive, alpha-beta t cell Naive b cell Naive regulatory t cell Myeloid dendritic cell, human

Blood

Normal

10x 3' v3

Cell

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Microglial cell Neuron Endothelial cell

Frontal cortex

54-year-old stage 73-year-old stage 72-year-old stage 61-year-old stage 70-year-old stage 59-year-old stage 58-year-old stage 50-year-old stage 51-year-old stage 68-year-old stage 66-year-old stage 56-year-old stage 43-year-old stage 71-year-old stage 47-year-old stage

Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia Amyotrophic lateral sclerosis Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Be cell Memory b cell Plasma cell Naive b cell Transitional stage b cell

Blood

35-year-old stage 62-year-old stage 27-year-old stage 26-year-old stage 61-year-old stage 57-year-old stage 36-year-old stage 12-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 58-year-old stage 64-year-old stage 29-year-old stage 11-year-old stage 33-year-old stage 32-year-old stage 28-year-old stage 31-year-old stage 63-year-old stage 60-year-old stage 25-year-old stage 56-year-old stage 65-year-old stage 34-year-old stage

Cytomegalovirus infection Normal

Female Male

10x 3' v3

Cell

Mus musculus

Astrocyte Leptomeningeal cell Gabaergic neuron Smooth muscle cell Oligodendrocyte precursor cell Oligodendrocyte Pericyte Glutamatergic neuron Macrophage Endothelial cell

Primary motor cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast Perivascular cell Placental villous trophoblast Hofbauer cell Macrophage Extravillous trophoblast Endothelial cell of placenta

Placenta

Carnegie stage 18 Carnegie stage 12 Carnegie stage 23 Carnegie stage 22 Carnegie stage 11 Carnegie stage 14 Carnegie stage 13 Carnegie stage 09

Toxoplasmosis Plasmodium malariae malaria Listeriosis Normal

Female

10x 3' v3

Cell