Homo sapiens

Naive b cell Transitional stage b cell Memory b cell Be cell Plasma cell

Blood

64-year-old stage 26-year-old stage 65-year-old stage 35-year-old stage 63-year-old stage 29-year-old stage 58-year-old stage 34-year-old stage 31-year-old stage 59-year-old stage 25-year-old stage 12-year-old stage 61-year-old stage 57-year-old stage 11-year-old stage 56-year-old stage 55-year-old stage 36-year-old stage 32-year-old stage 60-year-old stage 62-year-old stage 28-year-old stage 30-year-old stage 27-year-old stage 33-year-old stage

Normal Cytomegalovirus infection

Female Male

10x 3' v3

Cell

Mus musculus

Oligodendrocyte Pericyte Macrophage Leptomeningeal cell Oligodendrocyte precursor cell Endothelial cell Gabaergic neuron Smooth muscle cell Glutamatergic neuron Astrocyte

Primary motor cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast Extravillous trophoblast Macrophage Placental villous trophoblast Perivascular cell Endothelial cell of placenta Hofbauer cell

Placenta

Carnegie stage 18 Carnegie stage 14 Carnegie stage 23 Carnegie stage 12 Carnegie stage 22 Carnegie stage 09 Carnegie stage 11 Carnegie stage 13

Normal Toxoplasmosis Listeriosis Plasmodium malariae malaria

Female

10x 3' v3

Cell

Pan troglodytes

Oligodendrocyte L5/6 near-projecting glutamatergic neuron of the primary motor cortex L6b glutamatergic cortical neuron Pericyte Vascular leptomeningeal cell Sst gabaergic interneuron Inhibitory interneuron L2/3 intratelencephalic projecting glutamatergic neuron Macrophage T cell Lamp5 gabaergic interneuron Pvalb gabaergic interneuron L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex L6 corticothalamic-projecting glutamatergic cortical neuron Myeloid cell Erythroid lineage cell Oligodendrocyte precursor cell Microglial cell Endothelial cell Smooth muscle cell Pvalb chandelier gabaergic interneuron B cell Vip gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron Astrocyte

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Mature nk t cell Erythrocyte Neutrophil Mast cell Fibroblast Monocyte Malignant cell Macrophage T cell Hepatocyte Plasma cell Endothelial cell Chondrocyte B cell Keratinocyte

Axilla Bone spine Breast Liver Lung Neck

64-year-old stage 50-year-old stage 52-year-old stage 43-year-old stage 41-year-old stage 35-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 54-year-old stage 57-year-old stage 53-year-old stage 55-year-old stage 44-year-old stage 36-year-old stage 32-year-old stage 40-year-old stage 60-year-old stage 28-year-old stage 38-year-old stage 30-year-old stage

Breast cancer

Female

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Erythroblast Megakaryocyte Natural killer cell Endothelial cell of arteriole Interneuron Schwann cell Arachnoid barrier cell Neuroblast (sensu vertebrata) Mucosa-associated lymphoid tissue macrophage Capillary endothelial cell Mast cell Fibroblast Erythroid progenitor cell Monocyte Pericyte Common myeloid progenitor Fibroblast of choroid plexus Retinal cell Choroid plexus macrophage Meningeal macrophage Forebrain neuroblast Neural progenitor cell Dendritic cell Retinal ganglion cell Pinealocyte Tip cell Perivascular macrophage Vein endothelial cell Leptomeningeal cell Reticulocyte Forebrain radial glial cell Promyelocyte Epithelial cell Perivascular cell Oligodendrocyte precursor cell Neuronal-restricted precursor Platelet Metamyelocyte Microglial cell Glioblast (sensu vertebrata) Neural crest cell Mesenchymal cell Circulating fibrocyte Neuron Mesothelial cell of dura mater Endothelial cell Innate lymphoid cell Chondrocyte Smooth muscle cell Embryonic blood vessel endothelial progenitor cell Endothelial cell of artery Mechanoreceptor cell Mesenchyme condensation cell Schwann cell precursor B cell Radial glial cell Choroid plexus epithelial cell Spinal cord radial glial cell

Brain meninx Forebrain meninges Meninx

Carnegie stage 21 Carnegie stage 18 9th week post-fertilization stage 13th week post-fertilization stage Carnegie stage 23 12th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 16 Carnegie stage 20

Normal

Female Male

10x 3' v3

Cell

Mus musculus

Oligodendrocyte Olfactory receptor cell Natural killer cell Schwann cell Neutrophil Cd8-positive, alpha-beta t cell Granulocyte monocyte progenitor cell Ciliated epithelial cell Mast cell Fibroblast Monocyte Pericyte Alpha-beta t cell Group 3 innate lymphoid cell Tuft cell Neural progenitor cell Precursor b cell Group 2 innate lymphoid cell Macrophage Gamma-delta t cell Dendritic cell Osteoblast Epithelial cell Osteoclast Plasma cell Stromal cell Ionocyte Glandular secretory epithelial cell Goblet cell Plasmacytoid dendritic cell Vomeronasal sensory neuron Serous secreting cell Endothelial cell Chondrocyte Cd4-positive, alpha-beta t cell Smooth muscle cell B cell Hematopoietic stem cell Basal cell Sustentacular cell

Normal Influenza

10x 3' v3

Homo sapiens

Oligodendrocyte L6b glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron Vascular leptomeningeal cell Sst gabaergic interneuron Cerebral cortex endothelial cell Lamp5 gabaergic interneuron Pvalb gabaergic interneuron Oligodendrocyte precursor cell Sncg gabaergic interneuron Microglial cell Caudal ganglionic eminence derived interneuron Corticothalamic-projecting glutamatergic cortical neuron Astrocyte of the cerebral cortex L2/3-6 intratelencephalic projecting glutamatergic neuron Pvalb chandelier gabaergic interneuron Vip gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron

Middle temporal gyrus

50-year-old stage 43-year-old stage 29-year-old stage Adult stage 42-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3 Smart-seq v4

Nucleus

Homo sapiens

Mature nk t cell Erythroblast Peripheral nervous system neuron Ciliated epithelial cell Intestine goblet cell Pericyte Myeloid leukocyte Epithelial cell of lung Enteroendocrine cell Intestinal epithelial cell Mesothelial cell Glial cell Epithelial cell Hepatocyte Mesenchymal cell Endothelial cell Chondrocyte B cell Basal cell

Body of stomach Colon Duodenum Epithelium of trachea Esophagus Ileum Jejunum Liver Lung Pyloric antrum Small intestine Stomach

15th week post-fertilization stage 11th week post-fertilization stage 21st week post-fertilization stage Embryonic stage 9th week post-fertilization stage 13th week post-fertilization stage 19th week post-fertilization stage 12th week post-fertilization stage 17th week post-fertilization stage 18th week post-fertilization stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Astrocyte

Brodmann (1909) area 13 Brodmann (1909) area 14 Brodmann (1909) area 19 Brodmann (1909) area 23 Brodmann (1909) area 24 Brodmann (1909) area 25 Brodmann (1909) area 32 Brodmann (1909) area 35 Brodmann (1909) area 38 Brodmann (1909) area 40 Brodmann (1909) area 43 Brodmann (1909) area 46 Accessory basal amygdaloid nucleus Agranular insular cortex Anterior cortical amygdaloid nucleus Anterior nuclear group Anterior olfactory nucleus Basolateral amygdaloid nuclear complex Bed nucleus of stria terminalis Body of caudate nucleus Central amygdaloid nucleus Centromedian nucleus of thalamus Cerebellar nuclear complex Cerebellar vermis Cerebrocerebellum Claustrum of brain Corticomedial nuclear complex Cuneus cortex Dentate gyrus of hippocampal formation Dorsal tegmental nucleus Epithalamus Extrastriate cortex Globus pallidus Granular insular cortex Gray matter of midbrain Hippocampal field Hypothalamus Inferior frontal gyrus Inferior olivary complex Inferior temporal gyrus Intralaminar nuclear group Lateral amygdaloid nucleus Lateral entorhinal cortex Lateral geniculate body Lateral nuclear group of thalamus Lateral posterior nucleus of thalamus Mammillary body Medial dorsal nucleus of thalamus Medial entorhinal cortex Medial geniculate body Medial zone of hypothalamus Median tuberal portion Midbrain nucleus Midbrain tectum Middle temporal gyrus Nucleus accumbens Nucleus of dorsal thalamus Nucleus of medulla oblongata Parabrachial nucleus Perirhinal cortex Piriform cortex Pontine nuclear group Pontine reticular formation Pontine tegmentum Posterior parahippocampal gyrus Preoptic area Pretectal region Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Pulvinar nucleus Putamen Red nucleus Retrosplenial region Rostral ca3 Septal nuclear complex Spinal cord Subicular complex Substantia innominata Substantia nigra Subthalamic nucleus Superior parietal cortex Superior temporal gyrus Supraoptic nucleus Temporal fusiform gyrus Uncal ca1 Ventral anterior nucleus of thalamus

50-year-old stage 29-year-old stage 42-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Type l enteroendocrine cell Paneth cell Tuft cell Epithelial cell Enterocyte Stem cell Type ec enteroendocrine cell Goblet cell

Epithelium of small intestine Ileal epithelium Ileum Ileum lamina propria Lamina propria of small intestine Small intestine

Fifth decade stage Eighth decade stage Fourth decade stage Seventh decade stage Sixth decade stage Third decade stage

Normal Crohn disease

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Oligodendrocyte L6b glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron Vascular leptomeningeal cell Sst gabaergic interneuron Cerebral cortex endothelial cell Lamp5 gabaergic interneuron Pvalb gabaergic interneuron Oligodendrocyte precursor cell Sncg gabaergic interneuron Microglial cell Caudal ganglionic eminence derived interneuron Corticothalamic-projecting glutamatergic cortical neuron Astrocyte of the cerebral cortex L2/3-6 intratelencephalic projecting glutamatergic neuron Pvalb chandelier gabaergic interneuron Vip gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron

Primary somatosensory cortex

50-year-old stage 43-year-old stage 29-year-old stage 42-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus