Homo sapiens

Glioblast

Midbrain Midbrain tectum Striatum Cortex Hypothalamus Cerebral subcortex Metencephalon Basal forebrain Brain Forebrain Pons Cerebellum Entorhinal cortex Telencephalon Hippocampal formation Occipital cortex Diencephalon Upper layers of the cortex Hindbrain Caudate-putamen Lower layers of the cortex Cerebellar peduncular complex Frontal cortex Medulla oblongata Dorsal plus ventral thalamus

Carnegie stage 20 Carnegie stage 18 14th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 22 Carnegie stage 15 15th week post-fertilization stage 11th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage Carnegie stage 16

Normal

10x 3' v3 10x 3' v2

Cell

Heterocephalus glaber Mus musculus

Splenic red pulp macrophage Mast cell Splenic macrophage Granulocyte Naive t cell Neutrophil Cd8-alpha-positive cd11b-negative dendritic cell Cd4-positive, alpha-beta memory t cell Memory b cell Plasma cell Dendritic cell B cell Obsolete animal cell Marginal zone b cell of spleen Blood cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Erythroid lineage cell Type i nk t cell Cd8-positive, alpha-beta t cell Natural killer cell Erythrocyte Monocyte Cd8-positive, alpha-beta memory t cell T cell

Blood Spleen

2-month-old stage Post-juvenile adult stage

Normal

Female Male

10x genomics v2 Illumina

Mus musculus

Periportal region hepatocyte Liver dendritic cell Cholangiocyte Neutrophil B cell Centrilobular region hepatocyte Hepatic portal fibroblast Endothelial cell of hepatic sinusoid Macrophage Hepatic stellate cell T cell

Normal

10x 3' v3

Homo sapiens

Perivascular cell Mast cell Smooth muscle cell Stromal cell Plasma cell Fallopian tube secretory epithelial cell Peg cell Lymphocyte Endothelial cell of lymphatic vessel Macrophage Ciliated epithelial cell Endothelial cell

Fimbria of fallopian tube Ampulla of fallopian tube

62-year-old stage 72-year-old stage 61-year-old stage 42-year-old stage 48-year-old stage 70-year-old stage 40-year-old stage 55-year-old stage 32-year-old stage 37-year-old stage 43-year-old stage 65-year-old stage 44-year-old stage 47-year-old stage

Normal

Female

10x 3' v3 Drop-seq

Cell

Macaca mulatta

L6b glutamatergic cortical neuron Myeloid cell Astrocyte Lamp5 gabaergic interneuron Inhibitory interneuron Pvalb chandelier gabaergic interneuron Smooth muscle cell L2/3 intratelencephalic projecting glutamatergic neuron Vip gabaergic interneuron Oligodendrocyte precursor cell Oligodendrocyte B cell L6 corticothalamic-projecting glutamatergic cortical neuron Pericyte Erythroid lineage cell L5/6 near-projecting glutamatergic neuron of the primary motor cortex Pvalb gabaergic interneuron Macrophage Sst gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Vascular leptomeningeal cell Microglial cell T cell Endothelial cell

Dorsolateral prefrontal cortex

Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Innate lymphoid cell Mast cell Neutrophil Stromal cell Plasma cell B cell Plasmacytoid dendritic cell Eosinophil Cd8-positive, alpha-beta t cell Natural killer cell Macrophage Conventional dendritic cell Monocyte Cd4-positive, alpha-beta t cell Neuron Endothelial cell

Meningeal dura mater Brain Dura mater Brain meninx Bone marrow Subdural space Coronal suture

2-month-old stage Theiler stage 23 9-week-old stage 20-month-old stage and over 16-month-old stage Theiler stage 25 3-month-old stage

Normal

Female Male

10x 3' v3 10x 5' v1 10x 3' v2

Cell

Homo sapiens

Innate lymphoid cell Cd16-positive, cd56-dim natural killer cell, human Immature innate lymphoid cell Cd16-negative, cd56-bright natural killer cell, human Group 1 innate lymphoid cell Group 3 innate lymphoid cell

Lung Mesenteric lymph node Jejunal epithelium Blood Epithelial lining fluid Bone marrow Spleen Thoracic lymph node Jejunum lamina propria Inguinal lymph node

27-year-old stage 73-year-old stage Third decade stage Sixth decade stage Fourth decade stage 48-year-old stage Eighth decade stage 23-year-old stage 75-year-old stage 64-year-old stage 68-year-old stage 33-year-old stage Fifth decade stage 25-year-old stage 56-year-old stage 67-year-old stage 20-year-old stage

Normal

Female Male

10x 3' v3 10x 5' v2

Cell

Homo sapiens

Cardiac muscle cell

Normal

Spatial transcriptomics

Homo sapiens

Astrocyte Oligodendrocyte precursor cell Cerebral cortex neuron Oligodendrocyte Pyramidal neuron Interneuron Microglial cell Endothelial cell

Hippocampal formation

26-year-old stage 60-year-old stage 37-year-old stage 24-year-old stage 44-year-old stage

Epilepsy

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Lamp5 gabaergic interneuron Vip gabaergic interneuron Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron

Primary motor cortex Primary visual cortex Dorsolateral prefrontal cortex Primary somatosensory cortex Primary auditory cortex Middle temporal gyrus Anterior cingulate cortex Angular gyrus

Sixth decade stage 42-year-old stage 50-year-old stage 29-year-old stage 60-year-old stage 43-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Innate lymphoid cell Mast cell Intermediate monocyte Myeloid dendritic cell Hematopoietic precursor cell Neutrophil Stromal cell Cd8-positive, alpha-beta thymocyte Plasma cell B cell Regulatory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Non-classical monocyte Plasmacytoid dendritic cell Cd8-positive, alpha-beta t cell Natural killer cell Macrophage Erythrocyte Monocyte Cd4-positive, alpha-beta thymocyte Mature nk t cell Classical monocyte Cd4-positive, alpha-beta t cell T cell Endothelial cell

Mesenteric lymph node Inguinal lymph node Lymph node

61-year-old stage 45-year-old stage 59-year-old stage 69-year-old stage 60-year-old stage 56-year-old stage

Normal

Female Male

10x 3' v3 10x 5' v2 Smart-seq2

Cell

Homo sapiens

Hematopoietic multipotent progenitor cell Pro-b cell Common dendritic progenitor Plasma cell Early pro-b cell Immature b cell Hematopoietic stem cell Precursor b cell Plasmacytoid dendritic cell Megakaryocyte-erythroid progenitor cell Granulocyte monocyte progenitor cell Mature b cell Conventional dendritic cell Monocyte Mature nk t cell T cell Common lymphoid progenitor

Blood

11-month-old stage 7-month-old stage 9-month-old stage Newborn stage (0-28 days) 1-month-old stage 2-month-old stage 3-month-old stage 10-month-old stage 4-month-old stage 6-month-old stage 8-month-old stage

B-cell acute lymphoblastic leukemia

Female Male

10x 3' v3

Cell