Homo sapiens

T cell Neutrophil Hepatocyte Natural killer cell Endothelial cell Plasmacytoid dendritic cell Macrophage Cholangiocyte Plasma cell B cell Monocyte Basophil Conventional dendritic cell Fibroblast

Liver

66-year-old stage 75-year-old stage 53-year-old stage 68-year-old stage 55-year-old stage 28-year-old stage 72-year-old stage 49-year-old stage 58-year-old stage Adult stage 67-year-old stage 77-year-old stage 33-year-old stage 64-year-old stage 46-year-old stage 73-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus Cell

Homo sapiens

Activated cd4-positive, alpha-beta t cell, human Dendritic cell, human Cd14-positive, cd16-positive monocyte Endothelial cell Mature nk t cell Mast cell Effector cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Regulatory t cell Cd4-positive, alpha-beta t cell Cd14-positive monocyte Megakaryocyte B cell Abnormal cell Naive t cell Myofibroblast cell Conventional dendritic cell

Kidney Blood Lymph node

69-year-old stage 54-year-old stage 50-year-old stage 57-year-old stage 64-year-old stage 63-year-old stage

Clear cell renal carcinoma

Female Male

10x 5' v2

Cell

Mus musculus

Gabaergic neuron

Secondary somatosensory cortex Lateral septal complex Piriform cortex Hippocampal field Pallidum Orbitofrontal cortex Olfactory cortex Cerebral cortex Nucleus accumbens Primary somatosensory cortex Anterior olfactory nucleus Primary auditory cortex Primary motor cortex Caudate-putamen Dentate gyrus of hippocampal formation Anterior cerebral artery

Prime adult stage

Normal

Male

Scatac-seq

Nucleus

Homo sapiens

Mast cell Monocyte Dendritic cell

Ascitic fluid Diaphragm Caecum Peritoneum Parietal peritoneum Left ovary Liver Abdomen Urinary bladder Intestine Right ovary Adnexa of uterus Fallopian tube Large intestine Transverse colon Omentum Paracolic gutter Abdominal wall Lymph node

66-year-old stage 69-year-old stage 75-year-old stage 71-year-old stage 61-year-old stage 68-year-old stage 56-year-old stage 55-year-old stage 50-year-old stage 57-year-old stage 80 year-old and over stage 58-year-old stage 59-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage

Malignant ovarian serous tumor

Female

10x 3' v3

Cell

Homo sapiens

Glioblast Immature t cell Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Serotonergic neuron Oligodendrocyte Committed oligodendrocyte precursor Vascular leptomeningeal cell Neuroblast (sensu nematoda and protostomia) Schwann cell Leukocyte Dopaminergic neuron Microglial cell Neuroblast (sensu vertebrata) Radial glial cell Interneuron Glycinergic neuron Pericyte Progenitor cell Neuron Perivascular macrophage Purkinje cell Vascular associated smooth muscle cell Sensory neuron of dorsal root ganglion Gabaergic neuron Neural progenitor cell

Medulla oblongata Hindbrain Telencephalon Midbrain Cerebellum Brain Diencephalon Pons

13th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage 10th week post-fertilization stage Embryonic stage

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

T cell Neutrophil Stromal cell of endometrium Endothelial cell of lymphatic vessel Endothelial cell Mast cell Smooth muscle cell Preadipocyte Immature nk t cell Adipocyte Macrophage Mesothelial cell B cell Pericyte Monocyte Dendritic cell

Subcutaneous adipose tissue Omental fat pad

71-year-old stage 53-year-old stage 54-year-old stage 68-year-old stage 29-year-old stage 51-year-old stage 57-year-old stage 49-year-old stage 24-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 41-year-old stage 36-year-old stage 73-year-old stage

Normal

Female Male

10x 3' v3 Drop-seq

Nucleus Cell

Homo sapiens

Somatic stem cell Endothelial cell Intermediate mesodermal cell Schwann cell Paraxial cell Epithelial cell Mesodermal cell Splanchnic mesodermal cell Lateral mesodermal cell Sensory neuron Epidermal cell Endodermal cell Neuron Blood cell Fibroblast Primordial germ cell Neural progenitor cell

Embryoid body

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Cycling alveolar macrophage Lung interstitial macrophage Ccl3-positive alveolar macrophage Lipid-associated macrophage Macrophage Metallothionein-positive alveolar macrophage Alveolar macrophage

Lung

2-year-old stage 8-year-old stage 6-month-old stage 10-month-old stage 3-year-old stage 1-year-old stage 11-month-old stage 5-year-old stage 6-year-old stage 4-year-old stage

Cystic fibrosis Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Cd4-positive, alpha-beta t cell

T cell

Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Fourth decade stage Eighth decade stage Ninth decade stage

B-cell non-hodgkin lymphoma

Female Male

10x 5' v1

Cell

Homo sapiens

Hippocampal neuron Amygdala excitatory neuron Hippocampal ca1-3 neuron Dentate gyrus neuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L6 corticothalamic-projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron

Brodmann (1909) area 25 Corticomedial nuclear complex Insula Parietal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Claustrum of brain Inferior temporal gyrus Subiculum Pontine nuclear group Globus pallidus Piriform cortex Hippocampal field Prefrontal cortex Middle temporal gyrus Central amygdaloid nucleus Septal nuclear complex Brodmann (1909) area 38 Lateral entorhinal cortex Medial entorhinal cortex Central nucleus of inferior colliculus Agranular insular cortex Nucleus accumbens Substantia innominata Primary somatosensory cortex Pulvinar nucleus Primary auditory cortex Primary motor cortex Brodmann (1909) area 24 Brodmann (1909) area 46 Posterior parahippocampal gyrus Basolateral amygdaloid nuclear complex Hippocampal formation Granular insular cortex Anterior cingulate cortex Cuneus cortex Dentate gyrus of hippocampal formation Body of caudate nucleus Secondary visual cortex Bed nucleus of stria terminalis Putamen Amygdala

42-year-old stage 29-year-old stage 58-year-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

Hippocampal neuron Amygdala excitatory neuron Hippocampal ca1-3 neuron Dentate gyrus neuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L6 corticothalamic-projecting glutamatergic cortical neuron Near-projecting glutamatergic cortical neuron

Brodmann (1909) area 25 Corticomedial nuclear complex Insula Parietal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Claustrum of brain Inferior temporal gyrus Subiculum Pontine nuclear group Globus pallidus Piriform cortex Hippocampal field Prefrontal cortex Middle temporal gyrus Central amygdaloid nucleus Septal nuclear complex Brodmann (1909) area 38 Lateral entorhinal cortex Medial entorhinal cortex Central nucleus of inferior colliculus Agranular insular cortex Nucleus accumbens Substantia innominata Primary somatosensory cortex Pulvinar nucleus Primary auditory cortex Primary motor cortex Brodmann (1909) area 24 Brodmann (1909) area 46 Posterior parahippocampal gyrus Basolateral amygdaloid nuclear complex Hippocampal formation Granular insular cortex Anterior cingulate cortex Cuneus cortex Dentate gyrus of hippocampal formation Body of caudate nucleus Secondary visual cortex Bed nucleus of stria terminalis Putamen Amygdala

42-year-old stage 29-year-old stage 58-year-old stage

Normal

Male

Snmc-seq2

Nucleus

Homo sapiens

Neuron Neural progenitor cell

Forebrain

Carnegie stage 01

Normal

Female Male

10x 3' v3

Cell