Homo sapiens

Non-classical monocyte Natural killer cell Classical monocyte Cd8-positive, alpha-beta t cell Progenitor cell Plasmablast Lymphocyte Conventional dendritic cell Plasmacytoid dendritic cell Cd4-positive, alpha-beta t cell B cell

Blood

64-year-old stage 26-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 43-year-old stage 41-year-old stage 35-year-old stage 63-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 24-year-old stage 73-year-old stage 22-year-old stage 75-year-old stage 34-year-old stage 31-year-old stage 42-year-old stage 49-year-old stage 59-year-old stage 54-year-old stage 25-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage 21-year-old stage 83-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage 47-year-old stage 20-year-old stage 36-year-old stage 32-year-old stage 45-year-old stage 70-year-old stage 69-year-old stage 40-year-old stage 60-year-old stage 62-year-old stage 39-year-old stage 28-year-old stage 38-year-old stage 23-year-old stage 30-year-old stage 27-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage 33-year-old stage

Normal Systemic lupus erythematosus

Female Male

10x 3' v2

Cell

Homo sapiens

Natural killer cell Erythrocyte Naive b cell Transitional stage b cell Cd8-positive, alpha-beta t cell Regulatory t cell Cd14-positive monocyte Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Double negative thymocyte Naive thymus-derived cd4-positive, alpha-beta t cell Gamma-delta t cell Dendritic cell Cd14-low, cd16-positive monocyte Hematopoietic precursor cell Central memory cd4-positive, alpha-beta t cell Peripheral blood mononuclear cell Plasmablast Cd16-negative, cd56-bright natural killer cell, human Conventional dendritic cell Platelet Central memory cd8-positive, alpha-beta t cell Effector memory cd4-positive, alpha-beta t cell Mucosal invariant t cell Cd4-positive, alpha-beta cytotoxic t cell Plasmacytoid dendritic cell Innate lymphoid cell Cd4-positive, alpha-beta t cell Effector memory cd8-positive, alpha-beta t cell

Blood

85-year-old stage 80-year-old stage 64-year-old stage 26-year-old stage 91-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 82-year-old stage 43-year-old stage 41-year-old stage 35-year-old stage 63-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 24-year-old stage 73-year-old stage 22-year-old stage 75-year-old stage 93-year-old stage 84-year-old stage 34-year-old stage 31-year-old stage 42-year-old stage 49-year-old stage 86-year-old stage 59-year-old stage 54-year-old stage 25-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage 21-year-old stage 83-year-old stage 89-year-old stage 53-year-old stage 97-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage 77-year-old stage 94-year-old stage 78-year-old stage 47-year-old stage 20-year-old stage 36-year-old stage 32-year-old stage 45-year-old stage 70-year-old stage 81-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 40-year-old stage 95-year-old stage 88-year-old stage 90-year-old stage 87-year-old stage 60-year-old stage 62-year-old stage 19-year-old stage 39-year-old stage 28-year-old stage 38-year-old stage 23-year-old stage 30-year-old stage 79-year-old stage 72-year-old stage 27-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage 96-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Natural killer cell Memory regulatory t cell Erythrocyte Cd14-positive, cd16-negative classical monocyte Naive b cell Transitional stage b cell Memory ccr4-positive regulatory t cell Cd1c-positive myeloid dendritic cell Common myeloid progenitor Mature gamma-delta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Double negative thymocyte Axl+ dendritic cell, human Naive thymus-derived cd4-positive, alpha-beta t cell T cell Cd14-low, cd16-positive monocyte Central memory cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta memory t cell Cd8-positive, alpha-beta regulatory t cell Cd4-positive, alpha-beta memory t cell Cd16-negative, cd56-bright natural killer cell, human Be cell Common lymphoid progenitor Platelet Plasma cell Basophil mast progenitor cell Central memory cd8-positive, alpha-beta t cell Effector memory cd4-positive, alpha-beta t cell Mucosal invariant t cell Plasmacytoid dendritic cell Cd141-positive myeloid dendritic cell Cd8aa(i) thymocyte Innate lymphoid cell Cd16-positive, cd56-dim natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Naive regulatory t cell Intermediate monocyte

Blood

26-year-old stage 35-year-old stage 37-year-old stage 29-year-old stage 34-year-old stage 31-year-old stage 36-year-old stage 28-year-old stage 30-year-old stage 27-year-old stage

Cytomegalovirus infection

Female

10x 3' v3

Cell

Danio rerio

Retinal bipolar neuron Epithelial cell of esophagus Hatching gland cell Schwann cell Erythrocyte Neutrophil Cranial motor neuron Iridophore Splanchnic mesodermal cell Premigratory neural crest cell Migratory neural crest cell Neuroblast (sensu vertebrata) Xanthophore cell Pancreatic a cell Adaxial cell Type b pancreatic cell Hepatoblast Enteric neuron Neurecto-epithelial cell Pericyte Amacrine cell Notochordal cell Tendon cell Neuroplacodal cell Myeloid lineage restricted progenitor cell Kidney proximal convoluted tubule epithelial cell Ectodermal cell Rohon-beard neuron Mesodermal cell Myoblast Peridermal cell Motor neuron Connective tissue cell Endocrine cell Neural progenitor cell Purkinje cell Macrophage Pancreatic d cell Odontoblast Retinal ganglion cell Mesothelial cell Fast muscle myoblast Sensory hair cell Retinal pigment epithelial cell Multiciliated epithelial cell Spinal cord interneuron Osteoblast Glial cell Neuromast supporting cell Slow muscle cell Epidermal cell Xanthoblast Lens epithelial cell Epidermal mucus secreting cell Endodermal cell Epithelial cell Notochordal sheath cell Hepatocyte Muscle precursor cell Thyroid follicular cell Melanoblast Enterocyte Pancreatic endocrine cell Stromal cell Retinal progenitor cell Ionocyte Olfactory epithelial cell Photoreceptor cell Neural crest cell Kolmer-agduhr neuron Mesenchymal cell Taste receptor cell Goblet cell Notochordal vacuole cell Neuron Hypertrophic chondrocyte Muscle cell Auditory epithelial supporting cell Cardiac muscle cell Eye photoreceptor cell Nonkeratinized cell of epidermis Endothelial cell Cardiac endothelial cell Gabaergic neuron Primordial germ cell Chondrocyte Epithelial cell of exocrine pancreas Smooth muscle cell Glycinergic neuron Slow muscle myoblast Migratory cranial neural crest cell Podocyte Lateral motor column neuron Chondroblast Melanocyte Glutamatergic neuron Epithelial cell of distal tubule Fast muscle cell Lens fiber cell Retina horizontal cell

Adenohypophysis Anterior lateral plate mesoderm Anterior segment of eyeball Blood Blood island Blood vessel endothelium Brain Bulbus arteriosus Cerebellum Cleithrum Cloaca Corpuscles of stannius Cranial ganglion Craniocervical muscle Crista ampullaris Diencephalon Distal tubule Dorsolateral placode Ear vesicle Ectoderm-derived structure Endocardium Endocrine pancreas Enteric ganglion Epibranchial ganglion Esophagus Fast muscle tissue Floor plate Forebrain Ganglionic layer of retina Genitourinary system Gonad primordium Habenula Hatching gland Head Head connective tissue Heart Heart primordium Hindbrain Hypaxial musculature Hypochord Inner nuclear layer of retina Integument Interrenal primordium Intestinal epithelium Intestine Lateral line Lateral line ganglion Lateral plate mesoderm Lens of camera-type eye Lens vesicle Leptomeninx Liver Liver primordium Lymphatic vessel endothelium Macula Median fin fold Meninx Midbrain Midbrain tectum Midbrain tegmentum Midbrain-hindbrain boundary Multicellular anatomical structure Myotome Neural crest Neural rod Notochord Olfactory epithelium Olfactory system Outer nuclear layer of retina Pancreas Pancreatic epithelial bud Parachordal cartilage Pectoral appendage bud Pectoral fin Periderm Periocular mesenchyme Pharyngeal arch Pharyngeal pouch Pharynx Pigmented layer of retina Posterior neural tube Presomitic mesoderm Proepicardium Pronephric glomerulus Pronephric mesoderm Pronephros Proximal convoluted tubule Retina Sclerotome Semicircular canal Skin epidermis Slow muscle tissue Somite Spinal cord Swim bladder Taste bud Telencephalon Thyroid follicle Tooth placode Trigeminal ganglion Trunk neural crest Ventricular zone Vestibulocochlear ganglion Zona limitans intrathalamica

Pharyngula:high-pec Pharyngula:prim-5 Segmentation:20-25 somites Larval:protruding-mouth Segmentation:14-19 somites Pharyngula:prim-25 Pharyngula:prim-15 Hatching:long-pec Segmentation:26+ somites Hatching:pec-fin

Normal

Sci-rna-seq3

Nucleus

Homo sapiens

Natural killer cell Memory regulatory t cell Erythrocyte Cd14-positive, cd16-negative classical monocyte Naive b cell Transitional stage b cell Memory ccr4-positive regulatory t cell Cd1c-positive myeloid dendritic cell Common myeloid progenitor Mature gamma-delta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Double negative thymocyte Axl+ dendritic cell, human Naive thymus-derived cd4-positive, alpha-beta t cell T cell Cd14-low, cd16-positive monocyte Central memory cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta memory t cell Cd8-positive, alpha-beta regulatory t cell Cd4-positive, alpha-beta memory t cell Cd16-negative, cd56-bright natural killer cell, human Be cell Common lymphoid progenitor Platelet Plasma cell Basophil mast progenitor cell Central memory cd8-positive, alpha-beta t cell Effector memory cd4-positive, alpha-beta t cell Mucosal invariant t cell Plasmacytoid dendritic cell Cd141-positive myeloid dendritic cell Cd8aa(i) thymocyte Innate lymphoid cell Cd16-positive, cd56-dim natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Naive regulatory t cell Intermediate monocyte

Blood

26-year-old stage 35-year-old stage 37-year-old stage 29-year-old stage 34-year-old stage 31-year-old stage 36-year-old stage 32-year-old stage 28-year-old stage 30-year-old stage 27-year-old stage 33-year-old stage

Cytomegalovirus infection

Male

10x 3' v3

Cell

Mus musculus

Oligodendrocyte L5/6 near-projecting glutamatergic neuron of the primary motor cortex Cortical interneuron L6b glutamatergic cortical neuron Hippocampal neuron Pericyte Cajal-retzius cell Sst gabaergic interneuron Lamp5 gabaergic interneuron Pvalb gabaergic interneuron L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex L6 corticothalamic-projecting glutamatergic cortical neuron L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Central nervous system macrophage Sst chodl gabaergic interneuron Vascular leptomeningeal cell (mmus) L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Sncg gabaergic interneuron Pyramidal neuron Corticothalamic-projecting glutamatergic cortical neuron L2/3-6 intratelencephalic projecting glutamatergic neuron Endothelial cell Meis2 expressing cortical gabaergic cell Vip gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron Glutamatergic neuron Astrocyte

Agranular insular cortex Anterior cingulate cortex Auditory cortex Entorhinal cortex Frontal lobe Hippocampal formation Lateral visual area Medial orbital frontal cortex Parietal cortex Posterior parietal association areas Primary motor cortex Primary somatosensory cortex Primary visual cortex Retrosplenial granular cortex Subicular complex Temporal cortex Visual cortex

8-week-old stage 9-week-old stage 7-week-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Retinal blood vessel endothelial cell Mature nk t cell Retinal bipolar neuron Non-classical monocyte Bladder urothelial cell Natural killer cell Stromal cell of ovary Corneal epithelial cell Endothelial cell of arteriole Schwann cell Activated cd8-positive, alpha-beta t cell Erythrocyte Neutrophil Keratocyte Classical monocyte Cd8-positive, alpha-beta t cell Tongue muscle cell Type l enteroendocrine cell Colon endothelial cell Endothelial cell of lymphatic vessel Interstitial cell of cajal Pulmonary alveolar type 1 cell Medullary thymic epithelial cell Regulatory t cell Kidney epithelial cell Ciliated epithelial cell Pancreatic a cell Ovarian surface epithelial cell Theca cell Capillary endothelial cell Type b pancreatic cell Paneth cell of epithelium of small intestine Intrahepatic cholangiocyte Mast cell Vascular associated smooth muscle cell Myoepithelial cell Cd4-positive, alpha-beta thymocyte Leukocyte Pulmonary ionocyte Fibroblast Erythroid progenitor cell Spermatocyte Monocyte Mural cell Cd8-positive, alpha-beta thymocyte Pericyte Common myeloid progenitor Tendon cell Hematopoietic cell Club cell Alveolar adventitial fibroblast Enterocyte of epithelium of large intestine Myeloid leukocyte Basophil Large intestine goblet cell Mueller cell Fibroblast of breast Endothelial cell of vascular tree Paneth cell of colon Naive thymus-derived cd8-positive, alpha-beta t cell Enterochromaffin-like cell Progenitor cell of mammary luminal epithelium Connective tissue cell Activated cd4-positive, alpha-beta t cell Enteroendocrine cell Epithelial fate stem cell Mesenchymal stem cell Naive thymus-derived cd4-positive, alpha-beta t cell Macrophage Multiciliated columnar cell of tracheobronchial tree Leydig cell Gamma-delta t cell Pancreatic d cell T cell Hematopoietic precursor cell Retinal ganglion cell Transit amplifying cell of colon Mesothelial cell Retinal pigment epithelial cell Mononuclear phagocyte Stratified squamous epithelial cell Endothelial cell of venule Glial cell Vein endothelial cell Intestinal crypt stem cell of colon Slow muscle cell Blood vessel smooth muscle cell Myeloid cell Enterocyte of epithelium proper of ileum Small intestine goblet cell Myo-medullary thymic epithelial cell Ventricular cardiac muscle cell Serous cell of epithelium of bronchus Tuft cell of colon Sebocyte Pancreatic ductal cell Granulocyte Adipocyte Epithelial cell Hepatocyte Erythroid lineage cell Acinar cell of salivary gland Male germ cell Hepatic stellate cell Mesenchymal stem cell of adipose tissue Spermatid Langerhans cell Acinar cell Regular atrial cardiac myocyte Salivary gland cell Pulmonary alveolar type 2 cell Platelet Fibroblast of cardiac tissue Plasma cell Best4+ enterocyte Oocyte Microglial cell Stromal cell Ionocyte Peritubular myoid cell Neuro-medullary thymic epithelial cell Pancreatic stellate cell Enterocyte of epithelium proper of small intestine Conjunctival epithelial cell Glandular secretory epithelial cell Bronchial smooth muscle cell Mesenchymal cell Taste receptor cell Myofibroblast cell Neuron Muscle cell Tissue-resident macrophage Plasmacytoid dendritic cell Thymic fibroblast type 2 Myeloid dendritic cell Lung multiciliated epithelial cell Eye photoreceptor cell Pancreatic pp cell Endothelial cell Duct epithelial cell Cardiac endothelial cell Vestibular dark cell Innate lymphoid cell Supporting cell of vestibular epithelium Tracheal goblet cell Respiratory tract goblet cell Cd4-positive, alpha-beta t cell Myometrial cell Enteroendocrine cell of small intestine T follicular helper cell Luminal epithelial cell of mammary gland Serous cell of epithelium of trachea Smooth muscle cell Enterocyte of epithelium proper of duodenum Luminal cell of prostate epithelium Endothelial cell of artery Enterocyte of epithelium proper of jejunum Intermediate monocyte Pancreatic acinar cell B cell Enteroglial cell Adventitial cell Spermatogonium Thymic fibroblast type 1 Transit amplifying cell of small intestine Mucus secreting cell Melanocyte Intestinal tuft cell Radial glial cell Hematopoietic stem cell Basal cell of prostate epithelium Basal cell Fast muscle cell Epithelial cell of uterus Colon macrophage Thymocyte Intestinal crypt stem cell of small intestine Skeletal muscle satellite stem cell Retina horizontal cell

Abdominal aorta Adipose tissue Anterior part of tongue Anterior segment of eyeball Aorta Ascending colon Bladder organ Blood Bone marrow Brown adipose tissue Buccal mucosa Cardiac atrium Cardiac ventricle Chorioretinal region Conjunctiva Cornea Coronary artery Cortex of kidney Crista ampullaris Duodenum Endocrine pancreas Endometrium Exocrine pancreas Eye Eyelid Heart Heart right ventricle Ileum Inferior vena cava Inguinal lymph node Jejunum Kidney Lacrimal gland Large intestine Left coronary artery Left ovary Liver Lung Lymph node Mammary gland Mesenteric lymph node Mucosa of stomach Muscle of abdomen Muscle of pelvic diaphragm Muscularis mucosae of stomach Myometrium Ocular surface region Ovary Parotid gland Posterior part of tongue Posterior segment of eyeball Prostate gland Retinal neural layer Right cardiac atrium Right ovary Sclera Sigmoid colon Skin of abdomen Skin of body Skin of chest Small intestine Spleen Stomach Stomach smooth muscle Subcutaneous adipose tissue Sublingual gland Submandibular gland Testis Thoracic aorta Thymus Tongue Trachea Uterus Utricle of membranous labyrinth Vasculature

26-year-old stage 37-year-old stage 22-year-old stage 42-year-old stage 59-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 36-year-old stage 45-year-old stage 69-year-old stage 67-year-old stage 40-year-old stage 60-year-old stage 38-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v3 Smart-seq3 10x 5' v2 Smart-seq2

Cell

Homo sapiens

Oligodendrocyte Natural killer cell Neutrophil Mast cell Monocyte Mural cell Malignant cell Macrophage Dendritic cell Mature t cell Oligodendrocyte precursor cell Plasma cell Microglial cell Neuron Endothelial cell B cell Radial glial cell Astrocyte

Basal ganglion Brain Forebrain Frontal lobe Left frontal lobe Left parietal lobe Left temporal lobe Occipital lobe Parietal lobe Right frontal lobe Right occipital lobe Right parietal lobe Right temporal lobe Temporal lobe Temporoparietal junction

80-year-old stage 64-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 35-year-old stage 63-year-old stage 58-year-old stage 24-year-old stage Adult stage 34-year-old stage 42-year-old stage 59-year-old stage 54-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage 21-year-old stage 83-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage 77-year-old stage 78-year-old stage 36-year-old stage 45-year-old stage 70-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 60-year-old stage 62-year-old stage 72-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage 33-year-old stage

Glioblastoma

Female Male

Cel-seq2 10x 3' v2 10x 3' v3 Bd rhapsody whole transcriptome analysis Microwell-seq Smart-seq2 Strt-seq 10x 5' v1 Drop-seq

Cell Nucleus

Macaca mulatta

Glutamatergic neuron

Brodmann (1909) area 19 Amygdala Anterior cingulate cortex Cerebellar vermis Cerebrocerebellum Corpus callosum Dorsolateral prefrontal cortex Entorhinal cortex Head of caudate nucleus Hippocampal formation Inferior parietal cortex Inferior temporal gyrus Lateral geniculate body Medial dorsal nucleus of thalamus Medulla oblongata Midbrain Nucleus accumbens Perirhinal cortex Pons Prefrontal cortex Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Superior parietal cortex Superior temporal sulcus Ventral lateral nucleus of thalamus

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Schwann cell Mast cell Fibroblast Pericyte Myelinating schwann cell Macrophage Pigmented ciliary epithelial cell Trabecular meshwork cell Lymphocyte Non-pigmented ciliary epithelial cell Blood vessel endothelial cell Endothelial cell Ciliary muscle cell B cell Melanocyte

Ciliary body Eye trabecular meshwork Uvea

80 year-old and over stage 85-year-old stage 64-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 82-year-old stage 43-year-old stage 63-year-old stage 15-year-old stage 58-year-old stage 24-year-old stage 73-year-old stage 34-year-old stage 54-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 21-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 44-year-old stage 77-year-old stage 78-year-old stage 47-year-old stage 20-year-old stage 70-year-old stage 81-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 60-year-old stage 62-year-old stage 16-year-old stage 18-year-old stage 30-year-old stage 72-year-old stage 27-year-old stage 17-year-old stage 51-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Megakaryocyte Dendritic cell, human Parietal cell Interneuron Erythrocyte Naive b cell Follicular dendritic cell Endothelial cell of lymphatic vessel Interstitial cell of cajal Regulatory t cell Neuroblast (sensu vertebrata) Capillary endothelial cell Mast cell Vascular associated smooth muscle cell Myoepithelial cell Fibroblast Intestine goblet cell Immature pericyte Progenitor cell Monocyte Igg plasma cell Enteric neuron Pericyte Fibroblast of gingiva Cycling basal cell Mesodermal cell Group 3 innate lymphoid cell Paneth cell Motor neuron Naive thymus-derived cd8-positive, alpha-beta t cell T-helper 17 cell Memory b cell Type g enteroendocrine cell Precursor b cell Enteroendocrine cell Naive thymus-derived cd4-positive, alpha-beta t cell Trem2-positive macrophage Macrophage Gamma-delta t cell Tuft cell of small intestine Neutrophil progenitor cell Peptic cell Mesothelial cell Cd8-positive, alpha-beta memory t cell Plasmacytoid dendritic cell, human Plasmablast Cd4-positive, alpha-beta memory t cell Vein endothelial cell Type x enteroendocrine cell Cd16-negative, cd56-bright natural killer cell, human Eosinophil Foveolar cell of stomach Epithelial cell Intestinal crypt stem cell Acinar cell of salivary gland Colonocyte Mucous neck cell of gastric gland Pro-b cell Langerhans cell Conventional dendritic cell Cycling t cell Germinal center b cell Enterocyte Best4+ enterocyte Iga plasma cell Ionocyte Gastrointestinal tract (lamina propria) macrophage Transit amplifying cell Mucosal invariant t cell Fibroblastic reticular cell Type ec enteroendocrine cell Mesenchymal cell Myofibroblast cell M cell of gut Muscle cell Salivary gland glandular cell Endothelial cell Cd16-positive, cd56-dim natural killer cell, human T follicular helper cell Glandular cell of esophagus Smooth muscle cell Effector memory cd8-positive, alpha-beta t cell Endothelial cell of artery Enteroglial cell Keratinocyte Igm plasma cell Inhibitory motor neuron Melanocyte Afferent neuron Angiogenic pericyte Basal cell

Ascending colon Body of stomach Buccal mucosa Caecum Colon Colonic epithelium Colonic mucosa Descending colon Duodenal epithelium Duodenum Epithelium of esophagus Epithelium of rectum Epithelium of small intestine Epithelium of stomach Esophagus Gingiva Ileal epithelium Ileum Ileum lamina propria Intestine Jejunum Labial gland Lamina propria of mucosa of colon Lamina propria of small intestine Mesenteric lymph node Parotid gland Periodontium Pyloric antrum Pylorus Rectosigmoid junction Rectum Sigmoid colon Small intestine Stomach Transverse colon Vermiform appendix

85-year-old stage 6-year-old stage 80-year-old stage 15th week post-fertilization stage 26-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 43-year-old stage 41-year-old stage 2-month-old stage 35-year-old stage Fifth decade stage 63-year-old stage 37-year-old stage 11th week post-fertilization stage Juvenile stage (5-14 yo) 29-year-old stage 58-year-old stage 24-year-old stage 21st week post-fertilization stage Adult stage 22-year-old stage 75-year-old stage 84-year-old stage Embryonic stage 34-year-old stage Pediatric stage 31-year-old stage Carnegie stage 18 86-year-old stage 59-year-old stage 54-year-old stage 9-year-old stage 9th week post-fertilization stage 13th week post-fertilization stage 12-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage Eighth decade stage 19th week post-fertilization stage 21-year-old stage Carnegie stage 22 Fourth decade stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage 77-year-old stage Seventh decade stage 32-year-old stage 12th week post-fertilization stage 45-year-old stage 10th week post-fertilization stage 70-year-old stage 81-year-old stage 76-year-old stage 67-year-old stage 4-year-old stage Newborn stage (0-28 days) 17th week post-fertilization stage 16th week post-fertilization stage 87-year-old stage Young adult stage 60-year-old stage 62-year-old stage Sixth decade stage 10-year-old stage 39-year-old stage Carnegie stage 19 28-year-old stage Prime adult stage 23-year-old stage 30-year-old stage 18th week post-fertilization stage Carnegie stage 16 72-year-old stage Carnegie stage 17 48-year-old stage 51-year-old stage 33-year-old stage Third decade stage

Normal

Female Male

10x 3' v2 10x 3' v3 10x 5' transcription profiling 10x 5' v2 10x 3' v1 10x 5' v1

Cell

Mus musculus musculus

Oligodendrocyte Fibroblast Macrophage Glial cell Ependymal cell Oligodendrocyte precursor cell Microglial cell Brain microvascular endothelial cell Neuron Astrocyte

Normal

10x 3' v3