Homo sapiens

Innate lymphoid cell Plasmablast Effector memory cd4-positive, alpha-beta t cell Double negative thymocyte Peripheral blood mononuclear cell Mucosal invariant t cell Effector memory cd8-positive, alpha-beta t cell Cd14-low, cd16-positive monocyte Cd14-positive monocyte Cd4-positive, alpha-beta cytotoxic t cell Hematopoietic precursor cell Central memory cd4-positive, alpha-beta t cell Memory b cell Dendritic cell Gamma-delta t cell Regulatory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Cd8-positive, alpha-beta t cell Cd16-negative, cd56-bright natural killer cell, human Central memory cd8-positive, alpha-beta t cell Natural killer cell Platelet Erythrocyte Conventional dendritic cell Cd4-positive, alpha-beta t cell Naive b cell Transitional stage b cell

Blood

54-year-old stage 90-year-old stage 35-year-old stage 39-year-old stage 62-year-old stage 27-year-old stage 78-year-old stage 95-year-old stage 73-year-old stage 74-year-old stage 26-year-old stage 72-year-old stage 53-year-old stage 19-year-old stage 21-year-old stage 83-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage 96-year-old stage 82-year-old stage 49-year-old stage 42-year-old stage 36-year-old stage 52-year-old stage 86-year-old stage 48-year-old stage 70-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 23-year-old stage 58-year-old stage 75-year-old stage 22-year-old stage 50-year-old stage 51-year-old stage 79-year-old stage 89-year-old stage 64-year-old stage 68-year-old stage 29-year-old stage 66-year-old stage 77-year-old stage 94-year-old stage 33-year-old stage 93-year-old stage 69-year-old stage 32-year-old stage 28-year-old stage 76-year-old stage 31-year-old stage 88-year-old stage 87-year-old stage 63-year-old stage 60-year-old stage 97-year-old stage 80-year-old stage 84-year-old stage 25-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 91-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 20-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 34-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Innate lymphoid cell Effector memory cd4-positive, alpha-beta t cell Basophil mast progenitor cell Double negative thymocyte Mucosal invariant t cell Common myeloid progenitor Cd16-positive, cd56-dim natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Cd14-low, cd16-positive monocyte Be cell Intermediate monocyte Central memory cd4-positive, alpha-beta t cell Cd4-positive, alpha-beta memory t cell Cd141-positive myeloid dendritic cell Memory b cell Plasma cell Cd14-positive, cd16-negative classical monocyte Mature gamma-delta t cell Axl+ dendritic cell, human Cd1c-positive myeloid dendritic cell Naive thymus-derived cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta regulatory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Memory regulatory t cell Cd16-negative, cd56-bright natural killer cell, human Central memory cd8-positive, alpha-beta t cell Natural killer cell Platelet Erythrocyte Cd8-positive, alpha-beta memory t cell T cell Cd8aa(i) thymocyte Naive b cell Memory ccr4-positive regulatory t cell Naive regulatory t cell Transitional stage b cell Common lymphoid progenitor

Blood

35-year-old stage 27-year-old stage 26-year-old stage 36-year-old stage 30-year-old stage 29-year-old stage 28-year-old stage 31-year-old stage 37-year-old stage 34-year-old stage

Cytomegalovirus infection

Female

10x 3' v3

Cell

Danio rerio

Hepatoblast Pancreatic d cell Retinal ganglion cell Premigratory neural crest cell Sensory hair cell Notochordal vacuole cell Slow muscle cell Schwann cell Multiciliated epithelial cell Odontoblast Neural progenitor cell Fast muscle myoblast Kidney proximal convoluted tubule epithelial cell Ionocyte Pancreatic a cell Notochordal sheath cell Enterocyte Endodermal cell Neuroblast (sensu vertebrata) Kolmer-agduhr neuron Podocyte Cardiac endothelial cell Gabaergic neuron Glial cell Glycinergic neuron Myeloid lineage restricted progenitor cell Epidermal cell Spinal cord interneuron Taste receptor cell Amacrine cell Smooth muscle cell Peridermal cell Retina horizontal cell Retinal bipolar neuron Retinal progenitor cell Melanocyte Chondroblast Neutrophil Olfactory epithelial cell Epithelial cell Epithelial cell of distal tubule Stromal cell Splanchnic mesodermal cell Primordial germ cell Xanthoblast Cardiac muscle cell Purkinje cell Mesenchymal cell Chondrocyte Neuromast supporting cell Neurecto-epithelial cell Cranial motor neuron Epidermal mucus secreting cell Melanoblast Endocrine cell Retinal pigment epithelial cell Photoreceptor cell Thyroid follicular cell Motor neuron Pericyte Migratory cranial neural crest cell Hepatocyte Iridophore Lateral motor column neuron Goblet cell Xanthophore cell Mesodermal cell Slow muscle myoblast Muscle cell Muscle precursor cell Hatching gland cell Lens fiber cell Tendon cell Glutamatergic neuron Neuroplacodal cell Macrophage Migratory neural crest cell Hypertrophic chondrocyte Rohon-beard neuron Epithelial cell of exocrine pancreas Epithelial cell of esophagus Nonkeratinized cell of epidermis Erythrocyte Type b pancreatic cell Osteoblast Adaxial cell Myoblast Mesothelial cell Auditory epithelial supporting cell Ectodermal cell Notochordal cell Pancreatic endocrine cell Eye photoreceptor cell Enteric neuron Neuron Neural crest cell Lens epithelial cell Connective tissue cell Fast muscle cell Endothelial cell

Meninx Genitourinary system Gonad primordium Midbrain Lens vesicle Trigeminal ganglion Cleithrum Head connective tissue Cloaca Vestibulocochlear ganglion Outer nuclear layer of retina Midbrain tectum Pronephric glomerulus Pronephric mesoderm Periderm Integument Retina Trunk neural crest Crista ampullaris Pectoral appendage bud Notochord Pigmented layer of retina Hatching gland Adenohypophysis Liver Lens of camera-type eye Hypochord Anterior lateral plate mesoderm Myotome Midbrain tegmentum Blood Habenula Pectoral fin Fast muscle tissue Parachordal cartilage Midbrain-hindbrain boundary Lateral plate mesoderm Brain Inner nuclear layer of retina Median fin fold Pancreatic epithelial bud Distal tubule Forebrain Neural rod Slow muscle tissue Somite Cerebellum Blood island Macula Floor plate Ectoderm-derived structure Skin epidermis Ventricular zone Spinal cord Sclerotome Epibranchial ganglion Interrenal primordium Lateral line Hypaxial musculature Taste bud Telencephalon Ganglionic layer of retina Neural crest Intestine Pharyngeal pouch Ear vesicle Enteric ganglion Proximal convoluted tubule Pancreas Pronephros Pharynx Heart Diencephalon Bulbus arteriosus Esophagus Dorsolateral placode Lymphatic vessel endothelium Blood vessel endothelium Anterior segment of eyeball Proepicardium Cranial ganglion Periocular mesenchyme Craniocervical muscle Endocardium Zona limitans intrathalamica Hindbrain Leptomeninx Semicircular canal Corpuscles of stannius Lateral line ganglion Tooth placode Thyroid follicle Intestinal epithelium Pharyngeal arch Swim bladder Multicellular anatomical structure Endocrine pancreas Olfactory system Head Posterior neural tube Presomitic mesoderm Liver primordium Heart primordium Olfactory epithelium

Hatching:pec-fin Larval:protruding-mouth Pharyngula:prim-15 Pharyngula:prim-25 Segmentation:14-19 somites Pharyngula:high-pec Segmentation:26+ somites Hatching:long-pec Segmentation:20-25 somites Pharyngula:prim-5

Normal

Sci-rna-seq3

Nucleus

Homo sapiens

Innate lymphoid cell Effector memory cd4-positive, alpha-beta t cell Basophil mast progenitor cell Double negative thymocyte Mucosal invariant t cell Common myeloid progenitor Cd16-positive, cd56-dim natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Cd14-low, cd16-positive monocyte Be cell Intermediate monocyte Central memory cd4-positive, alpha-beta t cell Cd4-positive, alpha-beta memory t cell Cd141-positive myeloid dendritic cell Memory b cell Plasma cell Cd14-positive, cd16-negative classical monocyte Mature gamma-delta t cell Axl+ dendritic cell, human Cd1c-positive myeloid dendritic cell Naive thymus-derived cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta regulatory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Memory regulatory t cell Cd16-negative, cd56-bright natural killer cell, human Central memory cd8-positive, alpha-beta t cell Natural killer cell Platelet Erythrocyte Cd8-positive, alpha-beta memory t cell T cell Cd8aa(i) thymocyte Naive b cell Memory ccr4-positive regulatory t cell Naive regulatory t cell Transitional stage b cell Common lymphoid progenitor

Blood

35-year-old stage 27-year-old stage 26-year-old stage 36-year-old stage 30-year-old stage 29-year-old stage 33-year-old stage 32-year-old stage 28-year-old stage 31-year-old stage 37-year-old stage 34-year-old stage

Cytomegalovirus infection

Male

10x 3' v3

Cell

Mus musculus

Cortical interneuron L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex L6b glutamatergic cortical neuron Astrocyte Lamp5 gabaergic interneuron Sst chodl gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron Oligodendrocyte Pyramidal neuron L6 corticothalamic-projecting glutamatergic cortical neuron Pericyte Hippocampal neuron L5/6 near-projecting glutamatergic neuron of the primary motor cortex Pvalb gabaergic interneuron Meis2 expressing cortical gabaergic cell L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Glutamatergic neuron Cajal-retzius cell Sncg gabaergic interneuron Central nervous system macrophage Sst gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Endothelial cell Vascular leptomeningeal cell (mmus)

Primary motor cortex Medial orbital frontal cortex Primary visual cortex Primary somatosensory cortex Posterior parietal association areas Lateral visual area Retrosplenial granular cortex Temporal cortex Auditory cortex Agranular insular cortex Entorhinal cortex Hippocampal formation Anterior cingulate cortex Parietal cortex Visual cortex Frontal lobe Subicular complex

8-week-old stage 7-week-old stage 9-week-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Small intestine goblet cell Fibroblast Pancreatic d cell Salivary gland cell Pancreatic pp cell Serous cell of epithelium of trachea Innate lymphoid cell Enteroendocrine cell Regular atrial cardiac myocyte Pulmonary ionocyte Retinal ganglion cell Pancreatic ductal cell Enterocyte of epithelium proper of jejunum Slow muscle cell Schwann cell Luminal epithelial cell of mammary gland Endothelial cell of vascular tree Common myeloid progenitor Multiciliated columnar cell of tracheobronchial tree Intestinal crypt stem cell of small intestine Myeloid cell Ionocyte Pancreatic a cell Serous cell of epithelium of bronchus Pancreatic acinar cell Spermatid Mast cell Langerhans cell Stratified squamous epithelial cell Acinar cell Luminal cell of prostate epithelium Endothelial cell of arteriole Keratocyte Paneth cell of colon Cardiac endothelial cell Glial cell Paneth cell of epithelium of small intestine Granulocyte Vein endothelial cell Mesenchymal stem cell Intermediate monocyte Taste receptor cell Neuro-medullary thymic epithelial cell Progenitor cell of mammary luminal epithelium Epithelial cell of uterus Smooth muscle cell Intestinal tuft cell Myeloid dendritic cell Hematopoietic precursor cell Retina horizontal cell Mural cell Hematopoietic cell Retinal bipolar neuron Basophil Melanocyte Enterocyte of epithelium proper of small intestine Neutrophil Tracheal goblet cell Epithelial cell Enteroglial cell Conjunctival epithelial cell Stromal cell Mononuclear phagocyte Respiratory tract goblet cell Type l enteroendocrine cell Interstitial cell of cajal Cd8-positive, alpha-beta thymocyte Oocyte Enterocyte of epithelium of large intestine Enterochromaffin-like cell Plasma cell Colon endothelial cell B cell Gamma-delta t cell Regulatory t cell Mesenchymal cell Transit amplifying cell of small intestine Myoepithelial cell Leydig cell Intrahepatic cholangiocyte Vascular associated smooth muscle cell Large intestine goblet cell Capillary endothelial cell Erythroid progenitor cell Naive thymus-derived cd4-positive, alpha-beta t cell Medullary thymic epithelial cell Retinal pigment epithelial cell Mucus secreting cell Enterocyte of epithelium proper of ileum Myeloid leukocyte Pericyte Enterocyte of epithelium proper of duodenum Spermatogonium Myofibroblast cell Club cell Activated cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Ovarian surface epithelial cell Hepatocyte Vestibular dark cell Hematopoietic stem cell Non-classical monocyte Kidney epithelial cell Stromal cell of ovary Colon macrophage Pulmonary alveolar type 2 cell Plasmacytoid dendritic cell Skeletal muscle satellite stem cell Erythroid lineage cell Glandular secretory epithelial cell Activated cd8-positive, alpha-beta t cell Muscle cell Peritubular myoid cell Thymic fibroblast type 1 Leukocyte Adipocyte Alveolar adventitial fibroblast Duct epithelial cell Cd8-positive, alpha-beta t cell Endothelial cell of venule Basal cell of prostate epithelium Myo-medullary thymic epithelial cell Pulmonary alveolar type 1 cell Blood vessel smooth muscle cell Endothelial cell of lymphatic vessel Tendon cell Natural killer cell Macrophage Theca cell Tuft cell of colon Thymic fibroblast type 2 Hepatic stellate cell Ciliated epithelial cell Sebocyte Platelet Myometrial cell Bladder urothelial cell Transit amplifying cell of colon Bronchial smooth muscle cell Erythrocyte Best4+ enterocyte Type b pancreatic cell Mesenchymal stem cell of adipose tissue Radial glial cell Thymocyte Monocyte Mueller cell Cd4-positive, alpha-beta thymocyte Mature nk t cell Basal cell Corneal epithelial cell Supporting cell of vestibular epithelium Male germ cell Classical monocyte Retinal blood vessel endothelial cell Mesothelial cell Adventitial cell Pancreatic stellate cell Cd4-positive, alpha-beta t cell Microglial cell Fibroblast of cardiac tissue T cell Epithelial fate stem cell Spermatocyte Eye photoreceptor cell Lung multiciliated epithelial cell Neuron Intestinal crypt stem cell of colon Acinar cell of salivary gland Tongue muscle cell Enteroendocrine cell of small intestine T follicular helper cell Connective tissue cell Fast muscle cell Tissue-resident macrophage Fibroblast of breast Endothelial cell Ventricular cardiac muscle cell Endothelial cell of artery

Vasculature Skin of body Trachea Cardiac ventricle Chorioretinal region Myometrium Brown adipose tissue Left coronary artery Lacrimal gland Stomach Cortex of kidney Ascending colon Endometrium Sigmoid colon Lung Crista ampullaris Bladder organ Aorta Subcutaneous adipose tissue Mesenteric lymph node Liver Mucosa of stomach Conjunctiva Exocrine pancreas Ileum Blood Stomach smooth muscle Right cardiac atrium Muscle of abdomen Cornea Inferior vena cava Right ovary Prostate gland Skin of chest Abdominal aorta Large intestine Bone marrow Sclera Cardiac atrium Tongue Posterior part of tongue Kidney Sublingual gland Adipose tissue Eyelid Ovary Spleen Anterior part of tongue Thoracic aorta Uterus Muscle of pelvic diaphragm Small intestine Muscularis mucosae of stomach Thymus Left ovary Ocular surface region Buccal mucosa Posterior segment of eyeball Heart Skin of abdomen Retinal neural layer Jejunum Heart right ventricle Anterior segment of eyeball Coronary artery Duodenum Parotid gland Mammary gland Submandibular gland Testis Inguinal lymph node Lymph node Endocrine pancreas Eye Utricle of membranous labyrinth

74-year-old stage 26-year-old stage 61-year-old stage 57-year-old stage 42-year-old stage 36-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 59-year-old stage 55-year-old stage 22-year-old stage 33-year-old stage 69-year-old stage 60-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 67-year-old stage

Normal

Female Male

10x 3' v3 Smart-seq3 10x 5' v2 Smart-seq2

Cell

Homo sapiens

Astrocyte Mast cell Mural cell Neutrophil Oligodendrocyte precursor cell Malignant cell Plasma cell Oligodendrocyte Dendritic cell B cell Mature t cell Natural killer cell Macrophage Radial glial cell Monocyte Microglial cell Neuron Endothelial cell

Right temporal lobe Left frontal lobe Basal ganglion Parietal lobe Right parietal lobe Temporal lobe Brain Forebrain Right occipital lobe Occipital lobe Left temporal lobe Left parietal lobe Temporoparietal junction Frontal lobe Right frontal lobe

54-year-old stage 35-year-old stage Adult stage 62-year-old stage 78-year-old stage 74-year-old stage 72-year-old stage 53-year-old stage 21-year-old stage 83-year-old stage 61-year-old stage 57-year-old stage 42-year-old stage 36-year-old stage 52-year-old stage 48-year-old stage 70-year-old stage 45-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 50-year-old stage 51-year-old stage 64-year-old stage 68-year-old stage 66-year-old stage 77-year-old stage 33-year-old stage 69-year-old stage 76-year-old stage 63-year-old stage 60-year-old stage 80-year-old stage 56-year-old stage 46-year-old stage 24-year-old stage 67-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 34-year-old stage

Glioblastoma

Female Male

Microwell-seq Bd rhapsody whole transcriptome analysis Cel-seq2 10x 3' v3 Strt-seq Drop-seq Smart-seq2 10x 5' v1 10x 3' v2

Cell Nucleus

Macaca mulatta

Glutamatergic neuron

Primary motor cortex Perirhinal cortex Inferior temporal gyrus Midbrain Cerebrocerebellum Primary visual cortex Nucleus accumbens Dorsolateral prefrontal cortex Primary somatosensory cortex Medial dorsal nucleus of thalamus Lateral geniculate body Ventral lateral nucleus of thalamus Amygdala Brodmann (1909) area 19 Inferior parietal cortex Primary auditory cortex Cerebellar vermis Pons Entorhinal cortex Hippocampal formation Anterior cingulate cortex Prefrontal cortex Superior parietal cortex Superior temporal sulcus Corpus callosum Medulla oblongata Head of caudate nucleus

Prime adult stage Juvenile stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Fibroblast Pigmented ciliary epithelial cell Schwann cell Mast cell Myelinating schwann cell Melanocyte B cell Blood vessel endothelial cell Trabecular meshwork cell Pericyte Lymphocyte Macrophage Non-pigmented ciliary epithelial cell Ciliary muscle cell Endothelial cell

Eye trabecular meshwork Uvea Ciliary body

54-year-old stage 62-year-old stage 27-year-old stage 78-year-old stage 80 year-old and over stage 73-year-old stage 72-year-old stage 53-year-old stage 21-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage 82-year-old stage 17-year-old stage 52-year-old stage 70-year-old stage 30-year-old stage 58-year-old stage 15-year-old stage 18-year-old stage 50-year-old stage 51-year-old stage 64-year-old stage 68-year-old stage 66-year-old stage 77-year-old stage 69-year-old stage 76-year-old stage 63-year-old stage 60-year-old stage 56-year-old stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 20-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 34-year-old stage 16-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Iga plasma cell Fibroblast Afferent neuron Enteroendocrine cell Plasmablast Mucosal invariant t cell Inhibitory motor neuron Transit amplifying cell Keratinocyte Ionocyte Germinal center b cell Cd16-positive, cd56-dim natural killer cell, human Mast cell Langerhans cell Enterocyte Igg plasma cell Type x enteroendocrine cell Effector memory cd8-positive, alpha-beta t cell Dendritic cell, human Neuroblast (sensu vertebrata) Type ec enteroendocrine cell Vein endothelial cell Type g enteroendocrine cell Fibroblastic reticular cell Tuft cell of small intestine Smooth muscle cell Melanocyte Pro-b cell Epithelial cell Enteroglial cell Cd4-positive, alpha-beta memory t cell Interstitial cell of cajal Memory b cell Follicular dendritic cell Gamma-delta t cell Regulatory t cell Mesenchymal cell T-helper 17 cell Neutrophil progenitor cell Megakaryocyte Myoepithelial cell Vascular associated smooth muscle cell Capillary endothelial cell Naive thymus-derived cd4-positive, alpha-beta t cell Paneth cell Motor neuron Pericyte Salivary gland glandular cell Cycling basal cell Myofibroblast cell Angiogenic pericyte Fibroblast of gingiva Glandular cell of esophagus Naive thymus-derived cd8-positive, alpha-beta t cell Precursor b cell Plasmacytoid dendritic cell, human Intestine goblet cell Interneuron Mesodermal cell Muscle cell Eosinophil Progenitor cell Igm plasma cell Gastrointestinal tract (lamina propria) macrophage Endothelial cell of lymphatic vessel Trem2-positive macrophage Cd16-negative, cd56-bright natural killer cell, human Mucous neck cell of gastric gland Macrophage Foveolar cell of stomach Colonocyte Erythrocyte Best4+ enterocyte Group 3 innate lymphoid cell Conventional dendritic cell Monocyte Parietal cell Intestinal crypt stem cell Basal cell Cd8-positive, alpha-beta memory t cell Mesothelial cell Cycling t cell Enteric neuron Peptic cell Naive b cell Acinar cell of salivary gland Immature pericyte M cell of gut T follicular helper cell Endothelial cell Endothelial cell of artery

Epithelium of rectum Ileum lamina propria Ileal epithelium Epithelium of esophagus Stomach Ascending colon Sigmoid colon Transverse colon Pyloric antrum Caecum Colonic epithelium Colonic mucosa Mesenteric lymph node Ileum Vermiform appendix Descending colon Rectosigmoid junction Small intestine Duodenal epithelium Periodontium Body of stomach Intestine Buccal mucosa Esophagus Jejunum Epithelium of stomach Rectum Labial gland Duodenum Pylorus Gingiva Epithelium of small intestine Parotid gland Lamina propria of mucosa of colon Lamina propria of small intestine Colon

54-year-old stage 35-year-old stage Adult stage 39-year-old stage 62-year-old stage Carnegie stage 19 74-year-old stage 26-year-old stage 72-year-old stage 9-year-old stage 21st week post-fertilization stage Third decade stage Carnegie stage 18 10th week post-fertilization stage 21-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage Juvenile stage (5-14 yo) Sixth decade stage Newborn stage (0-28 days) Embryonic stage 4-year-old stage 16th week post-fertilization stage Fourth decade stage 52-year-old stage 86-year-old stage 48-year-old stage Carnegie stage 22 19th week post-fertilization stage 70-year-old stage 6-year-old stage 12-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage Eighth decade stage 30-year-old stage 10-year-old stage 2-month-old stage 55-year-old stage 23-year-old stage 58-year-old stage 75-year-old stage 22-year-old stage 50-year-old stage 51-year-old stage 68-year-old stage 29-year-old stage 66-year-old stage 15th week post-fertilization stage 77-year-old stage 11th week post-fertilization stage 13th week post-fertilization stage 33-year-old stage 32-year-old stage 12th week post-fertilization stage 28-year-old stage 76-year-old stage Young adult stage Fifth decade stage 31-year-old stage Carnegie stage 17 87-year-old stage 63-year-old stage 60-year-old stage 80-year-old stage Prime adult stage 18th week post-fertilization stage 84-year-old stage 56-year-old stage 37-year-old stage Pediatric stage 9th week post-fertilization stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 65-year-old stage 17th week post-fertilization stage Seventh decade stage 44-year-old stage 34-year-old stage Carnegie stage 16

Normal

Female Male

10x 5' transcription profiling 10x 3' v3 10x 3' v1 10x 5' v2 10x 5' v1 10x 3' v2

Cell

Mus musculus musculus

Fibroblast Astrocyte Glial cell Brain microvascular endothelial cell Oligodendrocyte precursor cell Oligodendrocyte Ependymal cell Macrophage Microglial cell Neuron

Normal

10x 3' v3

Homo sapiens

Innate lymphoid cell Effector memory cd4-positive, alpha-beta t cell Mucosal invariant t cell Cd16-positive, cd56-dim natural killer cell, human Cd14-low, cd16-positive monocyte Cd14-positive monocyte Cd4-positive, alpha-beta cytotoxic t cell Central memory cd4-positive, alpha-beta t cell Cd141-positive myeloid dendritic cell Memory b cell Plasma cell Dendritic cell B cell Gamma-delta t cell Regulatory t cell Cd1c-positive myeloid dendritic cell Naive thymus-derived cd4-positive, alpha-beta t cell Naive thymus-derived cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell Cd8-positive, alpha-beta t cell Cd16-negative, cd56-bright natural killer cell, human Natural killer cell Mature b cell Double negative t regulatory cell Platelet Erythrocyte Conventional dendritic cell Monocyte Cd8-positive, alpha-beta memory t cell Cd4-positive, alpha-beta t cell T cell Naive b cell Cd8-positive, alpha-beta cytotoxic t cell

Blood

54-year-old stage 35-year-old stage 39-year-old stage 62-year-old stage 27-year-old stage 73-year-old stage 26-year-old stage 72-year-old stage 53-year-old stage 19-year-old stage 21-year-old stage 61-year-old stage 57-year-old stage 49-year-old stage 42-year-old stage 36-year-old stage 52-year-old stage 48-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 23-year-old stage 58-year-old stage 75-year-old stage 22-year-old stage 50-year-old stage 51-year-old stage 64-year-old stage 68-year-old stage 29-year-old stage 66-year-old stage 33-year-old stage 69-year-old stage 32-year-old stage 28-year-old stage 31-year-old stage 63-year-old stage 60-year-old stage 25-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 34-year-old stage 47-year-old stage

Normal

Female Male

10x 5' v2

Cell