Homo sapiens

Myeloid cell Mast cell Mural cell Cardiac muscle cell Lymphocyte Adipocyte Cardiac neuron Fibroblast of cardiac tissue Endothelial cell

Heart left ventricle Apex of heart Interventricular septum Heart right ventricle

Third decade stage Postnatal stage Sixth decade stage Fourth decade stage Eighth decade stage Fifth decade stage Pediatric stage Seventh decade stage

Non-compaction cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Homo sapiens

Fibroblast Mast cell Endothelial cell of arteriole Myelinating schwann cell Melanocyte Plasma cell Dendritic cell B cell Non-myelinating schwann cell Retinal pigment epithelial cell Pericyte Endothelial cell of venule Blood vessel smooth muscle cell Natural killer cell Macrophage Platelet Fenestrated endothelial cell Monocyte Classical monocyte T cell Endothelial cell of artery

Chorioretinal region

62-year-old stage 27-year-old stage 80 year-old and over stage 72-year-old stage 21st week post-fertilization stage 53-year-old stage 14th week post-fertilization stage 21-year-old stage 81-year-old stage Newborn stage (0-28 days) 82-year-old stage 17-year-old stage 86-year-old stage 30-year-old stage 10-year-old stage 58-year-old stage 50-year-old stage 64-year-old stage 68-year-old stage 15th week post-fertilization stage 77-year-old stage 11-year-old stage 11th week post-fertilization stage 13th week post-fertilization stage 69-year-old stage 32-year-old stage 12th week post-fertilization stage 24th week post-fertilization stage 63-year-old stage 60-year-old stage 18th week post-fertilization stage 25-year-old stage 46-year-old stage 43-year-old stage 65-year-old stage 17th week post-fertilization stage 71-year-old stage 34-year-old stage 16-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3 10x 5' v2

Nucleus

Homo sapiens

Plasmablast Enucleated reticulocyte Mucosal invariant t cell Mast cell Dendritic cell B cell Gamma-delta t cell Blood cell Hematopoietic stem cell Non-classical monocyte Cd8-positive, alpha-beta t cell Megakaryocyte-erythroid progenitor cell Natural killer cell Double negative t regulatory cell Classical monocyte Cd4-positive, alpha-beta t cell Double-positive, alpha-beta thymocyte

Blood

Ninth decade stage Sixth decade stage Fourth decade stage Eighth decade stage 90 year-old and over stage Young adult stage Fifth decade stage Seventh decade stage

Covid-19 Influenza Normal

Female Male

10x 5' v1

Cell

Homo sapiens

Fibroblast Schwann cell Mast cell Keratocyte Myelinating schwann cell Smooth muscle cell Melanocyte Epithelial cell Conjunctival epithelial cell B cell Blood vessel endothelial cell Pericyte Lymphocyte Leukocyte Progenitor cell Endothelial cell of lymphatic vessel Macrophage Monocyte Corneal endothelial cell Endothelial cell

Tunica fibrosa of eyeball Corneal endothelium Cornea Sclera Ocular surface region Corneal epithelium Corneo-scleral junction Substantia propria of cornea

39-year-old stage 62-year-old stage 27-year-old stage 74-year-old stage 72-year-old stage 21st week post-fertilization stage 53-year-old stage 14th week post-fertilization stage 83-year-old stage Postnatal stage 61-year-old stage 13-year-old stage Newborn stage (0-28 days) 1-year-old stage 86-year-old stage 48-year-old stage 19th week post-fertilization stage 70-year-old stage 45-year-old stage 41-year-old stage Eighth decade stage 10-year-old stage 55-year-old stage 2-year-old stage 23rd week post-fertilization stage 75-year-old stage 90 year-old and over stage 22-year-old stage 51-year-old stage 64-year-old stage 20th week post-fertilization stage 15th week post-fertilization stage 77-year-old stage 11-year-old stage 11th week post-fertilization stage 13th week post-fertilization stage 33-year-old stage 69-year-old stage 32-year-old stage 22nd week post-fertilization stage 87-year-old stage 18th week post-fertilization stage 84-year-old stage 25-year-old stage 67-year-old stage 43-year-old stage 65-year-old stage 17th week post-fertilization stage 34-year-old stage 16-year-old stage

Normal

Female Male

10x multiome 10x 3' v3 10x 3' v2

Cell Nucleus

Mus musculus

Cytotoxic t cell Plasmablast Mucosal invariant t cell Common myeloid progenitor Follicular b cell Germinal center b cell Group 2 innate lymphoid cell Naive t cell Basophil Neutrophil Bm3 b cell Plasma cell Lymphoid tissue–inducer cell Cd103-positive dendritic cell T-helper 17 cell Centrocyte Natural t-regulatory cell Plasmacytoid dendritic cell Leukocyte Eosinophil Macrophage Marginal zone b cell of lymph node Group 3 innate lymphoid cell Conventional dendritic cell Mature nk t cell T cell Cycling t cell Naive b cell Transitional stage b cell

Normal

10x 3' v3

Homo sapiens

Hepatoblast Pancreatic d cell Enteroendocrine cell Kupffer cell Pancreatic ductal cell Schwann cell Epithelial cell of stomach Pancreatic a cell Colon epithelial cell Enterocyte Acinar cell Luminal cell of prostate epithelium Smooth muscle cell Intestinal tuft cell Hematopoietic cell Lung secretory cell Epithelial cell Stromal cell Pancreatic epsilon cell Interstitial cell of cajal Paneth cell Pericyte Club cell Pulmonary alveolar type 2 cell Goblet cell Mesodermal cell Pulmonary alveolar type 1 cell Hepatic stellate cell Neuroendocrine cell Epithelial cell of pancreas Best4+ enterocyte Type b pancreatic cell Ciliated cell Thymocyte Basal cell Mesothelial cell Neuron M cell of gut Stem cell Endothelial cell

Biliary system Nasopharynx Stomach Lung Pyloric antrum Corpus Liver Bronchus Ileum Prostate gland Thyroid gland Intestine Pancreas Alveolar sac Common bile duct Salivary gland epithelium Duodenum Lung epithelium Gallbladder Intrahepatic bile duct Colon

Normal

10x multiome Cel-seq2 Sort-seq 10x 3' v3 Seq-well s3 Smart-seq 10x 5' v1 10x 3' v2

Cell Nucleus

Homo sapiens

Perivascular cell Luminal epithelial cell of mammary gland Mural cell Mammary gland epithelial cell Blood vessel endothelial cell Leukocyte Endothelial cell of lymphatic vessel Fibroblast of mammary gland Luminal hormone-sensing cell of mammary gland Basal-myoepithelial cell of mammary gland Luminal adaptive secretory precursor cell of mammary gland

Breast

35-year-old stage 39-year-old stage 62-year-old stage 27-year-old stage 53-year-old stage 19-year-old stage 21-year-old stage 57-year-old stage 36-year-old stage 52-year-old stage 48-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 23-year-old stage 58-year-old stage 29-year-old stage 33-year-old stage 28-year-old stage 31-year-old stage 63-year-old stage 25-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 24-year-old stage 20-year-old stage 65-year-old stage 34-year-old stage

Normal

Female

10x 3' v3

Cell

Mus musculus Homo sapiens

Fibroblast Cerebellar granule cell Inhibitory interneuron Cerebellar neuron Cerebellar golgi cell Oligodendrocyte precursor cell Oligodendrocyte Astrocyte of the cerebellum Purkinje cell Bergmann glial cell Interneuron Obsolete excitatory neuron Ependymal cell Endothelial stalk cell Macrophage Microglial cell Endothelial cell

Normal

10x 3' v3

Homo sapiens

Common myeloid progenitor Pro-b cell Plasma cell B cell Hematopoietic stem cell Plasmacytoid dendritic cell Erythroid lineage cell Promonocyte Megakaryocyte-erythroid progenitor cell Granulocyte monocyte progenitor cell Natural killer cell Conventional dendritic cell Monocyte T cell

Bone marrow

54-year-old stage 35-year-old stage Adult stage 39-year-old stage 62-year-old stage 78-year-old stage 73-year-old stage 74-year-old stage 26-year-old stage 72-year-old stage 9-year-old stage 53-year-old stage 19-year-old stage 21-year-old stage 85-year-old stage 81-year-old stage 61-year-old stage 57-year-old stage 13-year-old stage 18-month-old stage 42-year-old stage 36-year-old stage 17-year-old stage 1-year-old stage 7-year-old stage 4-year-old stage 52-year-old stage 48-year-old stage 70-year-old stage 6-year-old stage 12-year-old stage 38-year-old stage 45-year-old stage 41-year-old stage 59-year-old stage 3-year-old stage 30-year-old stage 10-year-old stage 2-month-old stage 55-year-old stage 23-year-old stage 58-year-old stage 14-year-old stage 2-year-old stage 75-year-old stage 22-year-old stage 15-year-old stage 50-year-old stage 51-year-old stage 79-year-old stage 64-year-old stage 29-year-old stage 66-year-old stage 77-year-old stage 11-year-old stage 33-year-old stage 32-year-old stage 28-year-old stage 76-year-old stage 5-year-old stage 31-year-old stage 19-month-old stage 8-year-old stage 63-year-old stage 60-year-old stage 80-year-old stage 84-year-old stage 56-year-old stage 46-year-old stage 24-year-old stage 67-year-old stage 43-year-old stage 20-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 16-year-old stage 8-month-old stage 47-year-old stage

Myeloid leukemia Normal

Female Male

Sort-seq 10x 3' v3 Seq-well 10x 3' v1 10x 5' v2 Smart-seq2 10x transcription profiling 10x 5' v1 10x 3' v2

Cell

Homo sapiens

Effector memory cd4-positive, alpha-beta t cell Double negative thymocyte Central memory cd4-positive, alpha-beta t cell Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta regulatory t cell Memory regulatory t cell T cell Memory ccr4-positive regulatory t cell Naive regulatory t cell

Blood

35-year-old stage 62-year-old stage 27-year-old stage 26-year-old stage 61-year-old stage 57-year-old stage 36-year-old stage 12-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 58-year-old stage 64-year-old stage 29-year-old stage 11-year-old stage 33-year-old stage 32-year-old stage 28-year-old stage 31-year-old stage 63-year-old stage 60-year-old stage 25-year-old stage 56-year-old stage 65-year-old stage 34-year-old stage

Cytomegalovirus infection Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Fibroblast Myeloid cell Mast cell Smooth muscle cell Epithelial cell B cell Lymph node lymphatic vessel endothelial cell Pulmonary alveolar type 2 cell Lymphocyte Apoptosis fated cell Pulmonary alveolar type 1 cell Endothelial cell

Pulmonary systemic sclerosis Pulmonary fibrosis Normal Chronic obstructive pulmonary disease

10x 3' v3 10x 3' v1 10x 3' v2

Homo sapiens

Iga plasma cell Fibroblast Effector memory cd4-positive, alpha-beta t cell Class switched memory b cell Luminal epithelial cell of mammary gland Inflammatory macrophage Myeloid cell Mast cell Igg plasma cell Effector memory cd8-positive, alpha-beta t cell Unswitched memory b cell Vein endothelial cell Myeloid dendritic cell Neutrophil Mammary gland epithelial cell Gamma-delta t cell Regulatory t cell Vascular associated smooth muscle cell Capillary endothelial cell Pericyte Activated cd4-positive, alpha-beta t cell Non-classical monocyte Plasmacytoid dendritic cell Cd4-positive helper t cell Lymphocyte Activated cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Natural killer cell Macrophage Alternatively activated macrophage Conventional dendritic cell Mature nk t cell Basal cell Cd8-positive, alpha-beta memory t cell Classical monocyte Cd4-positive, alpha-beta t cell T cell Naive b cell Endothelial cell of artery

Breast

Adult stage Prime adult stage

Normal

Female

10x 3' v3 10x 3' v2

Cell