Homo sapiens

Natural killer cell Erythrocyte Naive b cell Cd8-positive, alpha-beta t cell Regulatory t cell Cd1c-positive myeloid dendritic cell Cd14-positive monocyte Monocyte Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Naive thymus-derived cd4-positive, alpha-beta t cell Gamma-delta t cell Dendritic cell T cell Cd14-low, cd16-positive monocyte Central memory cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta memory t cell Mature b cell Cd8-positive, alpha-beta cytotoxic t cell Cd16-negative, cd56-bright natural killer cell, human Conventional dendritic cell Double negative t regulatory cell Platelet Plasma cell Effector memory cd4-positive, alpha-beta t cell Mucosal invariant t cell Cd4-positive, alpha-beta cytotoxic t cell Plasmacytoid dendritic cell Cd141-positive myeloid dendritic cell Innate lymphoid cell Cd4-positive, alpha-beta t cell Cd16-positive, cd56-dim natural killer cell, human B cell

Blood

64-year-old stage 26-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 43-year-old stage 41-year-old stage 35-year-old stage 63-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 24-year-old stage 73-year-old stage 22-year-old stage 75-year-old stage 34-year-old stage 31-year-old stage 42-year-old stage 49-year-old stage 59-year-old stage 54-year-old stage 25-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 21-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage 47-year-old stage 36-year-old stage 32-year-old stage 45-year-old stage 69-year-old stage 67-year-old stage 40-year-old stage 60-year-old stage 62-year-old stage 19-year-old stage 39-year-old stage 28-year-old stage 38-year-old stage 23-year-old stage 30-year-old stage 72-year-old stage 27-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage 33-year-old stage

Normal

Female Male

10x 5' v2

Cell

Mus musculus

Erythroid progenitor cell

Embryo

Theiler stage 26 Theiler stage 16 Theiler stage 13 Theiler stage 14 Theiler stage 19 Theiler stage 25 Theiler stage 23 Theiler stage 17 Theiler stage 27 Theiler stage 20 Theiler stage 22 Theiler stage 12 Theiler stage 24 Theiler stage 21 Theiler stage 15 Theiler stage 18

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Oligodendrocyte Unipolar brush cell Interneuron Molecular layer interneuron Pericyte Cerebellar golgi cell Purkinje cell Oligodendrocyte precursor cell Microglial cell Granule cell Endothelial cell Bergmann glial cell Astrocyte

Normal Essential tremor

Parse evercode whole transcriptome v2

Homo sapiens

Erythroblast Oligodendrocyte Syncytiotrophoblast cell Professional antigen presenting cell Megakaryocyte Endocardial cell Unipolar brush cell Epithelial cell of thymus Corneal epithelial cell Schwann cell Endothelial cell of lymphatic vessel Cell of skeletal muscle Visceromotor neuron Ciliated epithelial cell Ganglion interneuron Mesangial cell Hepatoblast Enteric neuron Amacrine cell Hematopoietic cell Cortical cell of adrenal gland Squamous epithelial cell Epithelial cell of lower respiratory tract Mueller cell Neuron associated cell (sensu vertebrata) Tuft cell Endothelial cell of vascular tree Endocrine cell Inhibitory interneuron Purkinje cell Extravillous trophoblast Intestinal epithelial cell Stellate neuron Retinal ganglion cell Mesothelial cell Chorionic trophoblast cell Retinal pigment epithelial cell Glial cell Skeletal muscle satellite cell Myeloid cell Ventricular cardiac muscle cell Pancreatic ductal cell Hepatic stellate cell Blood vessel endothelial cell Acinar cell Regular atrial cardiac myocyte Trophoblast giant cell Microglial cell Stromal cell Photoreceptor cell Taste receptor cell Goblet cell Sympathetic neuron Neuron Chromaffin cell Granule cell Cardiac muscle cell Bipolar neuron Neuroendocrine cell Gabaergic neuron Innate lymphoid cell Macroglial cell Smooth muscle cell Dermis microvascular lymphatic vessel endothelial cell Glutamatergic neuron Epicardial adipocyte Hematopoietic stem cell Lens fiber cell Astrocyte Thymocyte Retina horizontal cell

Adrenal gland Cerebellum Eye Heart Intestine Kidney Liver Lung Muscle organ Pancreas Placenta Spleen Stomach Telencephalon Thymus

15th week post-fertilization stage 14th week post-fertilization stage 13th week post-fertilization stage 12th week post-fertilization stage 10th week post-fertilization stage 17th week post-fertilization stage 16th week post-fertilization stage 18th week post-fertilization stage

Normal Trisomy 18

Female Male

Sci-rna-seq3

Nucleus Cell

Homo sapiens

Oligodendrocyte Diffuse bipolar 3a cell Natural killer cell Retinal cone cell H2 horizontal cell Diffuse bipolar 6 cell Gabaergic amacrine cell Capillary endothelial cell Mast cell Vascular associated smooth muscle cell Retinal astrocyte S cone cell Diffuse bipolar 2 cell Fibroblast Diffuse bipolar 5 cell Pericyte Amacrine cell On parasol ganglion cell On-blue cone bipolar cell Rod bipolar cell Myelinating schwann cell Mueller cell Diffuse bipolar 4a cell Diffuse bipolar 4b cell Off parasol ganglion cell On midget ganglion cell Macrophage Dendritic cell T cell Retinal ganglion cell Non-myelinating schwann cell Retinal pigment epithelial cell Endothelial cell of venule Off midget ganglion cell Adipocyte Pigmented epithelial cell Flat midget bipolar cell Blood vessel endothelial cell Oligodendrocyte precursor cell Microglial cell Invaginating midget bipolar cell Diffuse bipolar 3b cell Diffuse bipolar 1 cell Giant bipolar cell Retinal rod cell H1 horizontal cell Fenestrated endothelial cell B cell Melanocyte Offx cell Glycinergic amacrine cell Astrocyte

Cranial nerve ii Optic disc

85-year-old stage 64-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 82-year-old stage 43-year-old stage 63-year-old stage 90 year-old and over stage 15-year-old stage 37-year-old stage 58-year-old stage 75-year-old stage 3-year-old stage 34-year-old stage 42-year-old stage 54-year-old stage 25-year-old stage 61-year-old stage 11-year-old stage 74-year-old stage 21-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 77-year-old stage 47-year-old stage 32-year-old stage 45-year-old stage 70-year-old stage 81-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage Newborn stage (0-28 days) 60-year-old stage 62-year-old stage 16-year-old stage 10-year-old stage 18-year-old stage 30-year-old stage 72-year-old stage 27-year-old stage 17-year-old stage 71-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Endothelial cell of lymphatic vessel Capillary endothelial cell Mast cell Vascular associated smooth muscle cell Fibroblast Pericyte Mesothelial cell Vein endothelial cell Myeloid cell Adipocyte Regular ventricular cardiac myocyte Lymphocyte Regular atrial cardiac myocyte Neuron Cardiac muscle cell Endothelial cell Smooth muscle cell Endothelial cell of artery

Apex of heart Heart left ventricle Heart right ventricle Interventricular septum Left cardiac atrium Right cardiac atrium

52-year-old stage 65-year-old stage 68-year-old stage 35-year-old stage Fifth decade stage 63-year-old stage 73-year-old stage 75-year-old stage 59-year-old stage 54-year-old stage 66-year-old stage 61-year-old stage Eighth decade stage 21-year-old stage 46-year-old stage 55-year-old stage 44-year-old stage Seventh decade stage 47-year-old stage 20-year-old stage 60-year-old stage 62-year-old stage Sixth decade stage 39-year-old stage 27-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3 10x 5' v1

Nucleus Cell

Homo sapiens

Mast cell Fibroblast Monocyte Dendritic cell T cell Plasma cell Fallopian tube secretory epithelial cell Endothelial cell B cell

Abdomen Abdominal wall Adnexa of uterus Ascitic fluid Caecum Diaphragm Fallopian tube Intestine Large intestine Left ovary Liver Lymph node Omentum Paracolic gutter Parietal peritoneum Peritoneum Right ovary Transverse colon Urinary bladder

80 year-old and over stage 64-year-old stage 50-year-old stage 68-year-old stage 41-year-old stage 63-year-old stage 58-year-old stage 75-year-old stage 59-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 77-year-old stage 78-year-old stage 47-year-old stage 45-year-old stage 70-year-old stage 76-year-old stage 69-year-old stage 60-year-old stage 71-year-old stage

Malignant ovarian serous tumor

Female

10x 3' v3

Cell

Mus musculus

Natural killer cell Endothelial cell of lymphatic vessel Regulatory t cell Mast cell Fibroblast Colon glandular cell Monocyte Malignant cell Macrophage Dendritic cell T cell Colon epithelial cell Intestinal crypt stem cell of colon Granulocyte Colonocyte Blood vessel endothelial cell Enteroendocrine cell of colon Myofibroblast cell B cell Cell

Colorectal carcinoma Normal

Spatial transcriptomics 10x 3' v2 10x 3' v3 Slide-seqv2

Homo sapiens

Megakaryocyte Cell of skeletal muscle Fibroblast Progenitor cell T cell Myeloid cell Granulocyte Erythroid lineage cell Innate lymphoid cell Smooth muscle cell B cell Cell

Normal

10x 3' v2 10x 5' v2

Homo sapiens

Megakaryocyte Natural killer cell Erythrocyte Neutrophil Late pro-b cell Cell of skeletal muscle Interstitial cell of cajal Regulatory t cell Granulocyte monocyte progenitor cell Fraction a pre-pro b cell Mast cell Vascular associated smooth muscle cell Fibroblast Promonocyte Monocyte Common myeloid progenitor Megakaryocyte-erythroid progenitor cell Group 3 innate lymphoid cell Epithelial cell of nephron Naive thymus-derived cd8-positive, alpha-beta t cell Enteroendocrine cell Group 2 innate lymphoid cell Double negative thymocyte Naive thymus-derived cd4-positive, alpha-beta t cell Macrophage B-2 b cell Dendritic cell Hematopoietic multipotent progenitor cell T cell Mesothelial cell Mature b cell Osteoblast Glial cell Skeletal muscle satellite cell Large pre-b-ii cell Common dendritic progenitor Small pre-b-ii cell Granulocyte Promyelocyte Epithelial cell Hepatocyte Osteoclast Pro-b cell Langerhans cell Kupffer cell Plasma cell B-1 b cell Eurydendroid cell Double-positive, alpha-beta thymocyte Stromal cell Myofibroblast cell Neuron Plasmacytoid dendritic cell Endothelial cell Early lymphoid progenitor Innate lymphoid cell Chondrocyte Myelocyte Smooth muscle cell Pre-conventional dendritic cell Immature b cell Keratinocyte Melanocyte Hematopoietic stem cell Cd8-alpha-alpha-positive, alpha-beta intraepithelial t cell

Bone marrow Gut wall Kidney Liver Mesenteric lymph node Skin of body Spleen Thymus Yolk sac

15th week post-fertilization stage 11th week post-fertilization stage 14th week post-fertilization stage 9th week post-fertilization stage 13th week post-fertilization stage Carnegie stage 23 Carnegie stage 22 12th week post-fertilization stage 10th week post-fertilization stage 17th week post-fertilization stage 16th week post-fertilization stage Carnegie stage 19 Carnegie stage 20 Carnegie stage 13

Normal

Female Male

10x 3' v2 10x 5' v1

Cell

Homo sapiens

Pulmonary artery endothelial cell Non-classical monocyte Natural killer cell Neutrophil Classical monocyte Cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Pulmonary alveolar type 1 cell Regulatory t cell Capillary endothelial cell Mast cell Cd1c-positive myeloid dendritic cell Pericyte Club cell Malignant cell Epithelial cell of lung Macrophage Dendritic cell Mesothelial cell Multiciliated epithelial cell Bronchus fibroblast of lung Vein endothelial cell Myeloid cell Conventional dendritic cell Pulmonary alveolar type 2 cell Plasma cell Stromal cell Alveolar macrophage Plasmacytoid dendritic cell Fibroblast of lung Cd4-positive, alpha-beta t cell Smooth muscle cell B cell

Adrenal tissue Brain Liver Lung Lymph node Pleural effusion

80-year-old stage 64-year-old stage 26-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 82-year-old stage 43-year-old stage 41-year-old stage 35-year-old stage 63-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 73-year-old stage 22-year-old stage 75-year-old stage 31-year-old stage 42-year-old stage 49-year-old stage 86-year-old stage 59-year-old stage 54-year-old stage 25-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage 21-year-old stage 83-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 77-year-old stage 78-year-old stage 47-year-old stage 20-year-old stage 36-year-old stage 32-year-old stage 45-year-old stage 70-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 40-year-old stage 60-year-old stage 62-year-old stage 28-year-old stage 23-year-old stage 79-year-old stage 72-year-old stage 48-year-old stage 51-year-old stage 71-year-old stage

Normal Non-small cell lung carcinoma Chronic obstructive pulmonary disease Lung adenocarcinoma Squamous cell lung carcinoma

Female Male

10x 3' v2 10x 3' v3 Bd rhapsody whole transcriptome analysis 10x 3' v1 Indrop Smart-seq2 10x 5' v1 Drop-seq Gexscope technology

Cell

Homo sapiens

Oligodendrocyte Vascular associated smooth muscle cell Fibroblast Pericyte Committed oligodendrocyte precursor Central nervous system macrophage Ependymal cell Oligodendrocyte precursor cell Microglial cell Endothelial cell Bergmann glial cell Choroid plexus epithelial cell Astrocyte

Brodmann (1909) area 13 Brodmann (1909) area 14 Brodmann (1909) area 19 Brodmann (1909) area 23 Brodmann (1909) area 24 Brodmann (1909) area 25 Brodmann (1909) area 32 Brodmann (1909) area 35 Brodmann (1909) area 38 Brodmann (1909) area 40 Brodmann (1909) area 43 Brodmann (1909) area 46 Accessory basal amygdaloid nucleus Agranular insular cortex Anterior cortical amygdaloid nucleus Anterior nuclear group Anterior olfactory nucleus Basolateral amygdaloid nuclear complex Bed nucleus of stria terminalis Body of caudate nucleus Central amygdaloid nucleus Centromedian nucleus of thalamus Cerebellar nuclear complex Cerebellar vermis Cerebrocerebellum Claustrum of brain Corticomedial nuclear complex Cuneus cortex Dentate gyrus of hippocampal formation Dorsal tegmental nucleus Epithalamus Extrastriate cortex Globus pallidus Granular insular cortex Gray matter of midbrain Hippocampal field Hypothalamus Inferior frontal gyrus Inferior olivary complex Inferior temporal gyrus Intralaminar nuclear group Lateral amygdaloid nucleus Lateral entorhinal cortex Lateral geniculate body Lateral nuclear group of thalamus Lateral posterior nucleus of thalamus Mammillary body Medial dorsal nucleus of thalamus Medial entorhinal cortex Medial geniculate body Medial zone of hypothalamus Median tuberal portion Midbrain nucleus Midbrain tectum Middle temporal gyrus Nucleus accumbens Nucleus of dorsal thalamus Nucleus of medulla oblongata Parabrachial nucleus Perirhinal cortex Piriform cortex Pontine nuclear group Pontine reticular formation Pontine tegmentum Posterior parahippocampal gyrus Preoptic area Pretectal region Primary auditory cortex Primary motor cortex Primary somatosensory cortex Primary visual cortex Pulvinar nucleus Putamen Red nucleus Retrosplenial region Rostral ca3 Septal nuclear complex Spinal cord Subicular complex Substantia innominata Substantia nigra Subthalamic nucleus Superior parietal cortex Superior temporal gyrus Supraoptic nucleus Temporal fusiform gyrus Uncal ca1 Ventral anterior nucleus of thalamus

50-year-old stage 29-year-old stage 42-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus