Mus musculus

Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Mature nk t cell Schwann cell Ependymal cell Macrophage Microglial cell Mature microglial cell Leptomeningeal cell Pericyte Neuron Astrocyte

Spinal cord

3-6 month-old mature stage

Spinal cord injury Normal

Female

10x 3' v2

Nucleus

Mus musculus

Club cell Aortic smooth muscle cell Endothelial cell of lymphatic vessel Multiciliated epithelial cell of the bronchus Endothelial cell of artery Capillary endothelial cell Pulmonary alveolar type 1 cell Vein endothelial cell Mesenchymal cell Mesothelial cell of visceral pleura Progenitor cell Mesenchymal stem cell Vascular associated smooth muscle cell Hematopoietic cell Pulmonary alveolar type 2 cell Enucleate erythrocyte

Lung

Theiler stage 27 Prime adult stage Theiler stage 25 2-week-old stage 7-day-old stage Theiler stage 21 Theiler stage 23

Normal

10x 3' v2

Cell

Homo sapiens

Dentate gyrus granule cell

Subthalamic nucleus Medial geniculate body Rostral ca3 Subicular complex Hippocampal field Middle temporal gyrus Substantia nigra Pulvinar nucleus Primary auditory cortex Primary motor cortex Dentate gyrus of hippocampal formation Lateral geniculate body

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus Tupaia belangeri Homo sapiens

Neuron

Normal

10x 3' v3

Homo sapiens

Hepatocyte Erythrocyte Endothelial cell Kupffer cell Mature nk t cell Hepatic stellate cell Lymphocyte Cholangiocyte Neoplastic cell B cell Neuron

Liver

Normal Blastoma

10x 3' v3

Nucleus

Homo sapiens

Natural killer cell Cd8-positive, alpha-beta t cell Platelet Erythroid lineage cell Cd16-positive, cd56-dim natural killer cell, human Cd4-positive, alpha-beta t cell Cd14-positive monocyte B cell Dendritic cell

Blood

91-year-old stage 65-year-old stage 89-year-old stage 71-year-old stage 85-year-old stage 61-year-old stage 68-year-old stage 48-year-old stage 39-year-old stage 50-year-old stage 80-year-old stage 81-year-old stage 74-year-old stage 58-year-old stage 67-year-old stage 77-year-old stage 70-year-old stage 60-year-old stage 78-year-old stage 73-year-old stage 83-year-old stage

Clonal hematopoiesis Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Microglial cell Neuron Astrocyte

Occipital cortex

66-year-old stage 65-year-old stage 88-year-old stage 68-year-old stage 84-year-old stage 74-year-old stage 58-year-old stage 67-year-old stage 62-year-old stage 70-year-old stage 63-year-old stage 73-year-old stage 83-year-old stage 96-year-old stage

Frontotemporal dementia Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Central memory cd4-positive, alpha-beta t cell Neutrophil Erythrocyte Small pre-b-ii cell Gamma-delta t cell Mature nk t cell Pro-b cell Mast cell Effector memory cd4-positive, alpha-beta t cell Erythroid lineage cell Classical monocyte Plasmacytoid dendritic cell, human Plasmacytoid dendritic cell Early lymphoid progenitor Megakaryocyte progenitor cell Common dendritic progenitor Thymocyte Effector memory cd8-positive, alpha-beta t cell, terminally differentiated Memory b cell Cd16-positive, cd56-dim natural killer cell, human Regulatory t cell Plasmablast Common myeloid progenitor Plasma cell Neutrophil progenitor cell Hematopoietic multipotent progenitor cell Megakaryocyte T follicular helper cell Granulocyte monocyte progenitor cell Mucosal invariant t cell Promyelocyte Megakaryocyte-erythroid progenitor cell Central memory cd8-positive, alpha-beta t cell Naive b cell Conventional dendritic cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Non-classical monocyte

Bone marrow

42-year-old stage Sixth decade stage 61-year-old stage 30-year-old stage 17-year-old stage Seventh decade stage 59-year-old stage 31-year-old stage 22-year-old stage Eighth decade stage

Normal

Female Male

10x 5' v2 10x 5' transcription profiling 10x 5' v1 Smart-seq2 10x 3' v3

Cell

Homo sapiens

T cell Neutrophil Bladder urothelial cell Natural killer cell Endothelial cell of lymphatic vessel Erythrocyte Endothelial cell Mature nk t cell Mast cell Cd8-positive, alpha-beta t cell Capillary endothelial cell Smooth muscle cell Macrophage Regulatory t cell Plasma cell Cd4-positive, alpha-beta t cell Vein endothelial cell B cell Pericyte Monocyte Myofibroblast cell Fibroblast

Bladder organ

61-year-old stage 56-year-old stage 59-year-old stage 45-year-old stage 60-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Homo sapiens

Neutrophil Club cell Respiratory tract goblet cell Serous cell of epithelium of bronchus Natural killer cell Endothelial cell of lymphatic vessel Mature nk t cell Mast cell Pulmonary ionocyte Cd8-positive, alpha-beta t cell Basal cell Endothelial cell of artery Capillary endothelial cell Classical monocyte Intermediate monocyte Plasmacytoid dendritic cell Myeloid dendritic cell Lung multiciliated epithelial cell Macrophage Pulmonary alveolar type 1 cell Bronchial smooth muscle cell Plasma cell Cd4-positive, alpha-beta t cell Vein endothelial cell Alveolar adventitial fibroblast Mesothelial cell B cell Pericyte Adventitial cell Monocyte Vascular associated smooth muscle cell Basophil Pulmonary alveolar type 2 cell Non-classical monocyte

Lung

61-year-old stage 59-year-old stage 60-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Mus musculus

T cell Natural killer cell Endothelial cell of lymphatic vessel Endothelial cell Epithelial cell Macrophage Mesenchymal stem cell of adipose tissue Mesothelial cell B cell Pericyte Monocyte Dendritic cell

Obesity disorder

10x 3' v3

Homo sapiens

Club cell Cd1c-positive myeloid dendritic cell Tracheobronchial serous cell Ciliated cell Natural killer cell Endothelial cell of lymphatic vessel Endothelial cell Myeloid dendritic cell, human Mature nk t cell Pulmonary ionocyte Pulmonary neuroendocrine cell Basal cell Effector memory cd4-positive, alpha-beta t cell Lung goblet cell Endothelial cell of artery Capillary endothelial cell Classical monocyte Intermediate monocyte Plasmacytoid dendritic cell, human Epithelial cell Lung multiciliated epithelial cell Lymphocyte Naive thymus-derived cd8-positive, alpha-beta t cell Mesothelial cell of pleura Macrophage Pulmonary alveolar type 1 cell Bronchial smooth muscle cell Respiratory basal cell Alveolar macrophage Plasma cell Vein endothelial cell Megakaryocyte Pulmonary interstitial fibroblast B cell Pericyte Naive thymus-derived cd4-positive, alpha-beta t cell Myeloid leukocyte Monocyte Mucus secreting cell Vascular associated smooth muscle cell Myofibroblast cell Fibroblast Dendritic cell Pulmonary alveolar type 2 cell Effector memory cd8-positive, alpha-beta t cell Non-classical monocyte

Lung Blood

75-year-old stage 51-year-old stage 46-year-old stage

Normal

Female Male

10x 3' v2

Cell