Homo sapiens

Hippocampal ca1-3 neuron

Subthalamic nucleus Medial geniculate body Brodmann (1909) area 25 Lateral amygdaloid nucleus Corticomedial nuclear complex Rostral ca3 Subicular complex Piriform cortex Hippocampal field Middle temporal gyrus Septal nuclear complex Supraoptic nucleus Medial entorhinal cortex Substantia nigra Brodmann (1909) area 14 Anterior olfactory nucleus Accessory basal amygdaloid nucleus Pulvinar nucleus Hypothalamus Primary motor cortex Brodmann (1909) area 46 Posterior parahippocampal gyrus Basolateral amygdaloid nuclear complex Retrosplenial region Dentate gyrus of hippocampal formation Mammillary body Uncal ca1 Bed nucleus of stria terminalis Lateral geniculate body

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Pancreatic a cell

Islet of langerhans

66-year-old stage 37-year-old stage 21-year-old stage 34-year-old stage 42-year-old stage 26-year-old stage 53-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 48-year-old stage 30-year-old stage 38-year-old stage 55-year-old stage 50-year-old stage 51-year-old stage 57-year-old stage 49-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 32-year-old stage 45-year-old stage 62-year-old stage 60-year-old stage 63-year-old stage 40-year-old stage

Prediabetes syndrome Normal Type 2 diabetes mellitus

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Endothelial cell of lymphatic vessel Mature nk t cell Mast cell Endothelial cell of artery Schwann cell Smooth muscle cell Adipocyte Macrophage Urothelial cell Plasma cell Vein endothelial cell Monocyte Vascular associated smooth muscle cell Fibroblast Dendritic cell

Ureteral orifice Ureterovesical junction Dome of urinary bladder Neck of urinary bladder

21-year-old stage 26-year-old stage 15-year-old stage 23-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Muscle cell Type ii muscle cell Type i muscle cell

Intercostal muscle

Sixth decade stage Third decade stage Seventh decade stage Fourth decade stage Eighth decade stage Young adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Mus musculus

Smooth muscle cell

Aorta

15-week-old stage 13-week-old stage 24-week-old stage 20-week-old stage 11-week-old stage 17-week-old stage 8-week-old stage

Atherosclerosis

Male

10x 3' v3

Cell

Callithrix jacchus

Neuron

Thalamic complex Medial dorsal nucleus of thalamus Ventral lateral nucleus of thalamus Lateral nuclear group of thalamus Ventral thalamus Dorsal thalamus Lateral geniculate body

Late adult stage Prime adult stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Pyramidal neuron Central nervous system macrophage Glutamatergic neuron L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Endothelial cell Oligodendrocyte Hippocampal neuron Meis2 expressing cortical gabaergic cell Vascular leptomeningeal cell (mmus) Lamp5 gabaergic interneuron Cajal-retzius cell L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron L6 corticothalamic-projecting glutamatergic cortical neuron Pvalb gabaergic interneuron Pericyte L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Sncg gabaergic interneuron Sst chodl gabaergic interneuron Astrocyte L5/6 near-projecting glutamatergic neuron of the primary motor cortex Sst gabaergic interneuron Cortical interneuron Corticothalamic-projecting glutamatergic cortical neuron

Auditory cortex Secondary somatosensory cortex Primary visual cortex Claustrum of brain Temporal cortex Subicular complex Prefrontal cortex Frontal cortex Lateral entorhinal cortex Gustatory cortex Medial entorhinal cortex Posterior parietal association areas Agranular insular cortex Primary somatosensory cortex Primary motor cortex Hippocampal formation Visual cortex Medial orbital frontal cortex Anterior cingulate cortex Retrosplenial region

9-week-old stage 15-week-old stage 13-week-old stage 12-week-old stage 14-week-old stage 11-week-old stage 7-week-old stage 10-week-old stage 8-week-old stage

Normal

Female Male

Smart-seq v4

Cell

Homo sapiens

Periportal region hepatocyte Blood vessel endothelial cell Natural killer cell Centrilobular region hepatocyte Kupffer cell Midzonal region hepatocyte Inflammatory macrophage Erythroid lineage cell Hepatic stellate cell Endothelial cell of pericentral hepatic sinusoid Cholangiocyte B cell

Caudate lobe of liver

Prime adult stage Young adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus Cell

Homo sapiens

Cardiac endothelial cell Endothelial cell of venule Endothelial cell of lymphatic vessel Endothelial cell Colon endothelial cell Endothelial cell of arteriole Endothelial cell of artery Capillary endothelial cell Endothelial cell of vascular tree Vein endothelial cell Retinal blood vessel endothelial cell

Inferior vena cava Skin of abdomen Skin of body Lung Ascending colon Heart right ventricle Thymus Brown adipose tissue Conjunctiva Stomach Testis Duodenum Inguinal lymph node Thoracic aorta Crista ampullaris Uterus Small intestine Anterior part of tongue Utricle of membranous labyrinth Exocrine pancreas Mucosa of stomach Left ovary Trachea Endometrium Aorta Coronary artery Cornea Sublingual gland Ileum Liver Endocrine pancreas Subcutaneous adipose tissue Ovary Right cardiac atrium Muscle of pelvic diaphragm Stomach smooth muscle Chorioretinal region Anterior segment of eyeball Cardiac ventricle Kidney Eye Right ovary Cardiac atrium Buccal mucosa Heart Abdominal aorta Sclera Submandibular gland Mammary gland Jejunum Myometrium Posterior segment of eyeball Large intestine Eyelid Spleen Muscle of abdomen Left coronary artery Parotid gland Lacrimal gland Lymph node Posterior part of tongue Bladder organ Bone marrow Adipose tissue Skin of chest Sigmoid colon Vasculature Prostate gland Mesenteric lymph node

69-year-old stage 37-year-old stage 26-year-old stage 61-year-old stage 38-year-old stage 56-year-old stage 55-year-old stage 57-year-old stage 74-year-old stage 59-year-old stage 67-year-old stage 33-year-old stage 45-year-old stage 46-year-old stage 60-year-old stage 36-year-old stage 40-year-old stage

Normal

Female Male

10x 5' v2 Smart-seq3 Smart-seq2 10x 3' v3

Cell

Homo sapiens

T cell Natural killer cell Mast cell Myeloid cell Plasma cell B cell

Pleural effusion Lung Axilla Liver Bone spine Brain Adrenal gland Lymph node

69-year-old stage 75-year-old stage 65-year-old stage 71-year-old stage 85-year-old stage 68-year-old stage 44-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 80-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 62-year-old stage 70-year-old stage 78-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage

Lung adenocarcinoma Normal Small cell lung carcinoma

Female Male

10x 3' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Diffuse bipolar 1 cell Diffuse bipolar 4 cell Diffuse bipolar 2 cell Offx cell Rod bipolar cell Invaginating midget bipolar cell Retinal bipolar neuron Flat midget bipolar cell Diffuse bipolar 3a cell On-blue cone bipolar cell Diffuse bipolar 6 cell Giant bipolar cell Diffuse bipolar 3b cell

Peripheral region of retina Macula lutea proper Fovea centralis Chorioretinal region Retinal neural layer

69-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 71-year-old stage 53-year-old stage 54-year-old stage 68-year-old stage 82-year-old stage 80-year-old stage 74-year-old stage Adult stage 64-year-old stage 86-year-old stage 60-year-old stage 78-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Dendritic cell, human Stromal cell Natural killer cell Cd8-positive, alpha-beta t cell Macrophage Cd4-positive, alpha-beta t cell B cell Monocyte

Cerebrospinal fluid

69-year-old stage 34-year-old stage 71-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 56-year-old stage 55-year-old stage 58-year-old stage 67-year-old stage 45-year-old stage 70-year-old stage 60-year-old stage 63-year-old stage 73-year-old stage 40-year-old stage

Glioblastoma Lymphoma Inflammatory disease Brain cancer

Female Male

10x 5' v2

Cell