Homo sapiens

L2/3 intratelencephalic projecting glutamatergic neuron Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Committed oligodendrocyte precursor Vascular leptomeningeal cell Cerebral cortex gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron Pvalb gabaergic interneuron Astrocyte Sst gabaergic interneuron

Lobe of cerebral hemisphere Frontal lobe Temporal lobe Parietal lobe

2-year-old stage 15-year-old stage 50-year-old stage 12-year-old stage 3-year-old stage 32-year-old stage 18-year-old stage 31-year-old stage

Isolated focal cortical dysplasia type ii

Female Male

10x multiome

Nucleus

Homo sapiens

Endocardial cell Endothelial cell Endothelial cell of artery Capillary endothelial cell Smooth muscle cell Adipocyte Cardiac mesenchymal cell Innate lymphoid cell Myeloid cell Fetal cardiomyocyte Vein endothelial cell Mesothelial cell of epicardium Cardiac muscle cell Pericyte Neuron Fibroblast

Heart right ventricle Basal zone of heart Right cardiac atrium Apex of heart Heart left ventricle Left cardiac atrium Interventricular septum

Sixth decade stage 10th week post-fertilization stage Seventh decade stage Embryonic stage Eighth decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Stromal cell Natural killer cell Endothelial cell of lymphatic vessel Secretory cell Endothelial cell Mast cell Smooth muscle cell Macrophage Ciliated epithelial cell B cell Pericyte

Ampulla of fallopian tube Fimbria of fallopian tube Isthmus of fallopian tube

65-year-old stage 61-year-old stage 55-year-old stage 72-year-old stage 62-year-old stage 70-year-old stage

Normal

Female

10x 3' v3 Drop-seq

Cell

Mus musculus

Osteoblast Ectodermal cell Neural cell Mesenchymal cell Blood cell Chondrocyte

Pharyngeal arch system

Theiler stage 22 Theiler stage 17 Theiler stage 19 Theiler stage 20 Theiler stage 21 Theiler stage 23

Normal

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Endothelial cell of lymphatic vessel Endothelial cell Endothelial cell of artery Capillary endothelial cell Vein endothelial cell

Ascending colon Colonic mucosa Stomach Duodenum Colonic epithelium Ileal epithelium Rectosigmoid junction Pyloric antrum Caecum Small intestine Gingiva Ileum Ileum lamina propria Colon Epithelium of esophagus Intestine Buccal mucosa Body of stomach Vermiform appendix Pylorus Rectum Esophagus Jejunum Transverse colon Periodontium Parotid gland Descending colon Sigmoid colon Labial gland Mesenteric lymph node

66-year-old stage 69-year-old stage Carnegie stage 19 37-year-old stage 75-year-old stage Pediatric stage 19th week post-fertilization stage 21-year-old stage 13-year-old stage 34-year-old stage 65-year-old stage 26-year-old stage Sixth decade stage 87-year-old stage 13th week post-fertilization stage 85-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 29-year-old stage 56-year-old stage Fifth decade stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 50-year-old stage 80-year-old stage 28-year-old stage 51-year-old stage 17th week post-fertilization stage 57-year-old stage 12-year-old stage 72-year-old stage 12th week post-fertilization stage Third decade stage 16th week post-fertilization stage 81-year-old stage 9th week post-fertilization stage 9-year-old stage 10th week post-fertilization stage 14-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage Seventh decade stage 58-year-old stage Embryonic stage 59-year-old stage Adult stage 67-year-old stage 18th week post-fertilization stage Carnegie stage 17 2-month-old stage 32-year-old stage 77-year-old stage 33-year-old stage Carnegie stage 22 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 31-year-old stage Fourth decade stage 22-year-old stage Newborn stage (0-28 days) Carnegie stage 16 Eighth decade stage 76-year-old stage Prime adult stage 11-year-old stage 6-year-old stage Young adult stage Carnegie stage 18 4-year-old stage 11th week post-fertilization stage Juvenile stage (5-14 yo)

Gastric cancer Inflammatory bowel disease Colorectal cancer Ulcerative colitis Normal Crohn disease

Female Male

10x 3' v1 10x 5' v2 10x 5' transcription profiling 10x 5' v1 10x 3' v3 10x 3' v2

Cell

Mus musculus

T cell Granulocyte Stromal cell Colon endothelial cell Lymph node lymphatic vessel endothelial cell Enteroglial cell Epithelial cell Plasma cell B cell Myofibroblast cell Mononuclear phagocyte

Normal

10x 3' v3

Homo sapiens

Blood vessel endothelial cell Endothelial cell of lymphatic vessel Secretory cell Mature nk t cell Mast cell Smooth muscle cell Macrophage Ciliated epithelial cell B cell Pericyte Myofibroblast cell Fibroblast

Ampulla of fallopian tube Fimbria of fallopian tube Fallopian tube Isthmus of fallopian tube

52-year-old stage 30-year-old stage 46-year-old stage 31-year-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Endothelial cell of umbilical vein

Endothelial cell

Newborn stage (0-28 days)

Normal

10x 3' v2

Cell

Homo sapiens

Effector cd8-positive, alpha-beta t cell Natural killer cell Erythrocyte Igg memory b cell Cd8-positive, alpha-beta t cell Platelet Cd4-positive helper t cell Classical monocyte Intermediate monocyte Effector cd4-positive, alpha-beta t cell Igg-negative class switched memory b cell Blood cell Dendritic cell Non-classical monocyte

Blood

75-year-old stage 61-year-old stage 54-year-old stage 68-year-old stage 38-year-old stage 56-year-old stage 82-year-old stage 67-year-old stage 62-year-old stage 70-year-old stage 46-year-old stage 78-year-old stage 63-year-old stage 73-year-old stage

Covid-19 Normal Influenza

Female Male

10x 3' v3

Cell

Homo sapiens

Natural killer cell Alpha-beta t cell Cd8-positive, alpha-beta t cell Platelet Plasmacytoid dendritic cell Plasmablast Cd4-positive, alpha-beta t cell B cell Monocyte Dendritic cell

Blood

80 year-old and over stage Adult stage 60-79 year-old stage

Covid-19 Normal

10x 5' v1

Cell

Homo sapiens

Midbrain-derived inhibitory neuron T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Dentate gyrus granule cell Cerebellar granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Cerebellar inhibitory gabaergic interneuron Ependymal cell Microglial cell Thalamic excitatory neuron B cell Pericyte Cerebral cortex neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron Mammillary body neuron Hippocampal ca4 neuron

Substantia nigra

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast

Heart right ventricle Right cardiac atrium Apex of heart Heart left ventricle Left cardiac atrium Interventricular septum

Sixth decade stage Fifth decade stage Seventh decade stage Eighth decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus Cell