Homo sapiens

T cell of anorectum Myeloid cell Colon epithelial cell Plasma cell Stromal cell of lamina propria of colon

Colonic mucosa

21-year-old stage 61-year-old stage 49-year-old stage 48-year-old stage 45-year-old stage 23-year-old stage 22-year-old stage 51-year-old stage 68-year-old stage 66-year-old stage 33-year-old stage 63-year-old stage 56-year-old stage 46-year-old stage 43-year-old stage 65-year-old stage

Crohn disease Normal Ulcerative colitis

Female Male

10x 3' v3

Cell

Mus musculus

Skin fibroblast

Skin of body Skin of back

12-month-old stage 2-month-old stage 5-week-old stage 7-week-old stage 22-day-old stage 9-week-old stage 21-day-old stage Prime adult stage 18-month-old stage

Injury Normal

Female Male

10x 3' v3 10x 3' v1 10x 3' v2

Cell

Homo sapiens

Fibroblast Mast cell Vein endothelial cell Alveolar macrophage Smooth muscle cell Epithelial cell Dendritic cell B cell Blood vessel endothelial cell Chondrocyte Vascular associated smooth muscle cell Pericyte Myofibroblast cell Club cell Pulmonary alveolar type 2 cell Goblet cell Enucleate erythrocyte Pulmonary alveolar type 1 cell Natural killer cell Macrophage Ciliated cell Monocyte Basal cell T cell Pulmonary neuroendocrine cell Endothelial cell Endothelial cell of artery

Lung

3-year-old stage 31st week post-fertilization stage 31-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Fibroblast Astrocyte Oligodendrocyte precursor cell Oligodendrocyte Vascular associated smooth muscle cell Bergmann glial cell Pericyte Leukocyte Ependymal cell Central nervous system macrophage Choroid plexus epithelial cell Neuron Endothelial cell

Pulvinar nucleus

42-year-old stage 50-year-old stage 29-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Exhausted t cell Gamma-delta t cell Regulatory t cell Cd4-positive helper t cell Effector cd8-positive, alpha-beta t cell Cd8-positive, alpha-beta memory t cell

Adrenal gland Lung Pleural effusion Liver Brain Bone spine Axilla Lymph node

62-year-old stage 78-year-old stage 73-year-old stage 74-year-old stage 72-year-old stage 85-year-old stage 81-year-old stage 57-year-old stage 82-year-old stage 70-year-old stage 55-year-old stage 75-year-old stage 79-year-old stage 64-year-old stage 68-year-old stage 77-year-old stage 69-year-old stage 76-year-old stage 80-year-old stage 84-year-old stage 67-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 47-year-old stage

Normal Lung adenocarcinoma Small cell lung carcinoma

Female Male

10x 3' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Cardiac endothelial cell Lymphoid lineage restricted progenitor cell Cardiac muscle myoblast Neuronal receptor cell Pericyte Immature innate lymphoid cell Smooth muscle myoblast Fibroblast of cardiac tissue

Heart left ventricle

74-year-old stage 61-year-old stage 57-year-old stage 52-year-old stage 40-year-old stage 38-year-old stage 59-year-old stage 55-year-old stage 58-year-old stage 51-year-old stage 64-year-old stage 66-year-old stage 63-year-old stage 60-year-old stage 43-year-old stage 44-year-old stage 47-year-old stage

Myocardial infarction Normal

Female Male

10x scatac-seq

Nucleus

Mus musculus

Striosomal d1 medium spiny neuron Astrocyte Neuroblast (sensu vertebrata) Contractile cell Oligodendrocyte Indirect pathway medium spiny neuron Cholinergic neuron Interneuron Neural cell Ependymal cell Glutamatergic neuron Neuron associated cell Neural stem cell Direct pathway medium spiny neuron Vascular leptomeningeal cell Microglial cell Endothelial cell

Postnatal subventricular zone

5-week-old stage

Normal

Mixed sex

10x genomics v2

Homo sapiens

Neural progenitor cell Astrocyte Inhibitory interneuron Oligodendrocyte precursor cell Medial ganglionic eminence derived interneuron Caudal ganglionic eminence derived interneuron Oligodendrocyte Vascular associated smooth muscle cell Pericyte Glutamatergic neuron Radial glial cell Microglial cell Endothelial cell

Dorsolateral prefrontal cortex Cortical plate

39-year-old stage Infant stage 4-year-old stage 19th week post-fertilization stage 6-year-old stage 14-year-old stage 23rd week post-fertilization stage 24th week post-fertilization stage 18th week post-fertilization stage 20-year-old stage

Normal

Female Male

10x multiome

Nucleus

Homo sapiens

Astrocyte Cerebellar granule cell Gabaergic neuron Committed oligodendrocyte precursor Mural cell Oligodendrocyte precursor cell Oligodendrocyte Vascular associated smooth muscle cell Capillary endothelial cell Leukocyte Glutamatergic neuron Central nervous system macrophage Microglial cell Neuron Endothelial cell of artery

Brodmann (1909) area 4 Cervical spinal cord white matter White matter of cerebellum

39-year-old stage 73-year-old stage 74-year-old stage 72-year-old stage 61-year-old stage 42-year-old stage 40-year-old stage 45-year-old stage 63-year-old stage 37-year-old stage 71-year-old stage 44-year-old stage 34-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

L2/3-6 intratelencephalic projecting glutamatergic neuron

Middle temporal gyrus

Adult stage 78-year-old stage 80 year-old and over stage 72-year-old stage 83-year-old stage 85-year-old stage 81-year-old stage 82-year-old stage 86-year-old stage 70-year-old stage 75-year-old stage 50-year-old stage 89-year-old stage 68-year-old stage 29-year-old stage 77-year-old stage 69-year-old stage 88-year-old stage 87-year-old stage 60-year-old stage 80-year-old stage 84-year-old stage 43-year-old stage 65-year-old stage

Dementia Normal

Female Male

10x multiome 10x 3' v3

Nucleus

Homo sapiens

Neuron

Intralaminar nuclear group Primary motor cortex Perirhinal cortex Inferior temporal gyrus Dentate gyrus of hippocampal formation Primary visual cortex Ventral anterior nucleus of thalamus Brodmann (1909) area 46 Subthalamic nucleus Globus pallidus Nucleus accumbens Primary somatosensory cortex Midbrain tectum Lateral nuclear group of thalamus Inferior frontal gyrus Epithalamus Cuneus cortex Retrosplenial region Medial dorsal nucleus of thalamus Medial zone of hypothalamus Putamen Lateral geniculate body Brodmann (1909) area 25 Nucleus of medulla oblongata Red nucleus Corticomedial nuclear complex Nucleus of dorsal thalamus Brodmann (1909) area 14 Brodmann (1909) area 19 Piriform cortex Pontine tegmentum Accessory basal amygdaloid nucleus Anterior olfactory nucleus Hypothalamus Granular insular cortex Centromedian nucleus of thalamus Brodmann (1909) area 32 Superior temporal gyrus Substantia nigra Primary auditory cortex Brodmann (1909) area 24 Uncal ca1 Anterior cortical amygdaloid nucleus Lateral entorhinal cortex Septal nuclear complex Basolateral amygdaloid nuclear complex Preoptic area Middle temporal gyrus Brodmann (1909) area 38 Agranular insular cortex Pulvinar nucleus Body of caudate nucleus Temporal fusiform gyrus Extrastriate cortex Brodmann (1909) area 23 Medial entorhinal cortex Lateral amygdaloid nucleus Supraoptic nucleus Posterior parahippocampal gyrus Pontine nuclear group Median tuberal portion Superior parietal cortex Dorsal tegmental nucleus Substantia innominata Bed nucleus of stria terminalis Brodmann (1909) area 13 Medial geniculate body Gray matter of midbrain Mammillary body Anterior nuclear group Central amygdaloid nucleus Subicular complex Brodmann (1909) area 43 Hippocampal field Rostral ca3 Brodmann (1909) area 40 Claustrum of brain Pretectal region Lateral posterior nucleus of thalamus

42-year-old stage 50-year-old stage 29-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Secretory cell Fibroblast Myeloid cell Mast cell Basal cell of olfactory epithelium Neutrophil Plasma cell Goblet cell Glandular secretory epithelial cell Eosinophil Macrophage Ciliated cell T cell Endothelial cell

Normal Chronic rhinitis

Seq-well