Homo sapiens

Neutrophil Transit amplifying cell of small intestine Endothelial cell of venule Natural killer cell Endothelial cell of lymphatic vessel Enterocyte of epithelium proper of small intestine Gamma-delta t cell Activated cd4-positive, alpha-beta t cell Best4+ enterocyte Mast cell Cd8-positive, alpha-beta t cell Endothelial cell of arteriole Enteroglial cell Intestinal tuft cell Myeloid dendritic cell Enterocyte of epithelium proper of jejunum Enterocyte of epithelium proper of duodenum Small intestine goblet cell Macrophage Innate lymphoid cell Regulatory t cell Paneth cell of epithelium of small intestine Activated cd8-positive, alpha-beta t cell Enteroendocrine cell of small intestine Enterocyte of epithelium proper of ileum Plasma cell Cd4-positive, alpha-beta t cell B cell Pericyte Naive thymus-derived cd4-positive, alpha-beta t cell Intestinal crypt stem cell of small intestine Monocyte Myofibroblast cell Fibroblast

Duodenum Small intestine Ileum Jejunum

37-year-old stage 61-year-old stage 56-year-old stage 59-year-old stage 60-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Mus musculus

Tracheal epithelial cell

Tracheal epithelial cell

Mature stage

Normal

10x 3' v3

Cell

Homo sapiens

Cardiac endothelial cell Pluripotent stem cell Hematopoietic stem cell Progenitor cell

Embryo Embryoid body Dorsal lateral plate region

Carnegie stage 11 Carnegie stage 14 Carnegie stage 13 Carnegie stage 10 Carnegie stage 17 Carnegie stage 16 Carnegie stage 15

Normal

Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Natural killer cell Gamma-delta t cell Mast cell Cd8-positive, alpha-beta t cell Colon macrophage Iga plasma cell Plasmacytoid dendritic cell T-helper 17 cell Macrophage Memory b cell Follicular b cell Innate lymphoid cell Regulatory t cell Cd4-positive, alpha-beta t cell T follicular helper cell B cell T-helper 1 cell Monocyte Conventional dendritic cell Dendritic cell Memory t cell

Caecum Transverse colon Sigmoid colon Mesenteric lymph node

Sixth decade stage Fifth decade stage Seventh decade stage

Normal

Female Male

10x 5' v2 10x 3' v2

Cell

Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Dentate gyrus granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Ependymal cell Microglial cell B cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast

Subicular complex

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Central memory cd4-positive, alpha-beta t cell Igg plasmablast Neutrophil Activated cd4-positive, alpha-beta t cell, human Natural killer cell Erythrocyte Gamma-delta t cell Platelet Classical monocyte Plasmacytoid dendritic cell, human Lymphocyte Naive thymus-derived cd8-positive, alpha-beta t cell Memory b cell Regulatory t cell Iga plasmablast Hematopoietic stem cell Naive thymus-derived cd4-positive, alpha-beta t cell Mucosal invariant t cell Transitional stage b cell Naive b cell Double negative thymocyte Conventional dendritic cell Cd16-negative, cd56-bright natural killer cell, human Effector memory cd8-positive, alpha-beta t cell Immature neutrophil Non-classical monocyte

Blood

37-year-old stage Sixth decade stage 48-year-old stage Fifth decade stage Third decade stage 80 year-old and over stage 49-year-old stage Seventh decade stage 36-year-old stage Fourth decade stage

Covid-19 Normal

Female Male

Seq-well

Cell

Drosophila melanogaster

Neuron Fat cell Adult olfactory receptor neuron or88a Tracheolar cell Adult olfactory receptor neuron or67d Adult olfactory receptor neuron or47b Glial cell Male germline cell Hemocyte Johnston organ neuron Epithelial cell Muscle cell Adult glial cell Adult olfactory receptor neuron gr21a/63a Sensory neuron Oenocyte Adult olfactory receptor neuron ir75d Neuron Adult olfactory receptor neuron or92a Adult olfactory receptor neuron or65 Adult olfactory receptor neuron or13a Female germline cell

Antenna

Day 5 of adulthood

Normal

Mixed sex Female Male

10x 3' v3

Homo sapiens

Neutrophil Endothelial cell Lymphocyte Mural cell Fibroblast Mononuclear phagocyte

Left atrium auricular region

Sixth decade stage Fifth decade stage Seventh decade stage Eighth decade stage Ninth decade stage

Mitral valve insufficiency Atrial fibrillation Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Cd8-positive, alpha-beta t cell Exhausted t cell Cd4-positive helper t cell Regulatory t cell Myeloid cell Plasma cell Malignant cell T follicular helper cell B cell

Lymph node

Adult stage

Metastatic melanoma

Slide-seqv2

Homo sapiens

Cd14-positive, cd16-positive monocyte Natural killer cell Activated cd4-positive, alpha-beta t cell Mature nk t cell Mast cell Cd4-positive, alpha-beta cytotoxic t cell Cd8-positive, alpha-beta cytotoxic t cell Macrophage Activated cd8-positive, alpha-beta t cell B cell Monocyte Dendritic cell

Heart right ventricle Right cardiac atrium Apex of heart Heart left ventricle Left cardiac atrium Interventricular septum

Sixth decade stage Fifth decade stage Seventh decade stage Eighth decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus Cell

Homo sapiens

Kupffer cell Plasmacytoid dendritic cell Macrophage Myeloid leukocyte Monocyte Conventional dendritic cell Non-classical monocyte

Liver

66-year-old stage 75-year-old stage 53-year-old stage 55-year-old stage 28-year-old stage 72-year-old stage 49-year-old stage Adult stage 77-year-old stage 46-year-old stage 73-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Midbrain-derived inhibitory neuron T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Cerebellar granule cell Hippocampal ca1-3 neuron Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Cerebellar inhibitory gabaergic interneuron Ependymal cell Microglial cell Thalamic excitatory neuron Choroid plexus epithelial cell Bergmann glial cell B cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron Hippocampal ca4 neuron

Septal nuclear complex

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus