Mus musculus

Glutamatergic neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Macrophage Astrocyte Gabaergic neuron

Primary motor cortex

Prime adult stage

Normal

Female

10x 3' v3

Nucleus

Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Microglial cell B cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Monocyte Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron

Claustrum of brain

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Eccentric medium spiny neuron

Brodmann (1909) area 25 Lateral amygdaloid nucleus Anterior nuclear group Corticomedial nuclear complex Medial dorsal nucleus of thalamus Claustrum of brain Globus pallidus Piriform cortex Hippocampal field Lateral nuclear group of thalamus Brodmann (1909) area 13 Central amygdaloid nucleus Ventral anterior nucleus of thalamus Septal nuclear complex Epithalamus Lateral entorhinal cortex Supraoptic nucleus Medial entorhinal cortex Brodmann (1909) area 40 Inferior frontal gyrus Substantia nigra Agranular insular cortex Brodmann (1909) area 43 Nucleus accumbens Substantia innominata Anterior cortical amygdaloid nucleus Brodmann (1909) area 14 Anterior olfactory nucleus Accessory basal amygdaloid nucleus Primary auditory cortex Hypothalamus Primary motor cortex Brodmann (1909) area 24 Brodmann (1909) area 46 Basolateral amygdaloid nuclear complex Perirhinal cortex Granular insular cortex Dentate gyrus of hippocampal formation Lateral posterior nucleus of thalamus Superior temporal gyrus Body of caudate nucleus Uncal ca1 Bed nucleus of stria terminalis Superior parietal cortex Lateral geniculate body Putamen Preoptic area

42-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Microglial cell

Middle temporal gyrus

69-year-old stage 75-year-old stage 65-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 85-year-old stage 88-year-old stage 68-year-old stage 29-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 72-year-old stage 81-year-old stage 80 year-old and over stage Adult stage 77-year-old stage 86-year-old stage 70-year-old stage 60-year-old stage 78-year-old stage 83-year-old stage

Normal Dementia

Female Male

10x multiome 10x 3' v3

Nucleus

Mus musculus

Adipocyte

Periovarian fat pad Inguinal fat pad Epididymal fat pad

19-week-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

T cell Neutrophil Natural killer cell Endothelial cell of lymphatic vessel Tissue-resident macrophage Endothelial cell Mature nk t cell Hematopoietic precursor cell Mast cell Cd8-positive, alpha-beta t cell Basal cell Endothelial cell of artery Leukocyte Classical monocyte Ionocyte Intermediate monocyte Myeloid dendritic cell Myoepithelial cell Macrophage Duct epithelial cell Acinar cell of salivary gland Plasma cell Cd4-positive, alpha-beta t cell B cell Pericyte Adventitial cell Monocyte Vascular associated smooth muscle cell Fibroblast Non-classical monocyte Salivary gland cell

Sublingual gland Submandibular gland Parotid gland

69-year-old stage 59-year-old stage 45-year-old stage 60-year-old stage

Normal

Female Male

Smart-seq2 10x 3' v3

Cell

Homo sapiens

T cell Club cell Endothelial cell of lymphatic vessel Endothelial cell Lung multiciliated epithelial cell Pulmonary alveolar type 1 cell Fibroblast of lung Monocyte Pulmonary alveolar type 2 cell

Lung

75-year-old stage 44-year-old stage 56-year-old stage 50-year-old stage 49-year-old stage 45-year-old stage 46-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage

Normal

Female Male

10x 3' v2

Cell

Homo sapiens

Classical monocyte Intermediate monocyte Plasmacytoid dendritic cell Monocyte Dendritic cell Non-classical monocyte

Blood

Sixth decade stage Fifth decade stage Seventh decade stage Fourth decade stage

Covid-19 Normal

Female Male

10x 5' v2 10x 5' v1

Cell

Homo sapiens

Natural killer cell Basal cell of epithelium of lobular bronchiole Capillary endothelial cell Plasmacytoid dendritic cell, human Plasmacytoid dendritic cell Macrophage Regulatory t cell Activated cd8-positive, alpha-beta t cell Parietal cell Plasma cell Salivary gland glandular cell Malignant cell Cd4-positive, alpha-beta memory t cell Pericyte Mucous cell of stomach Conventional dendritic cell Muscle fibroblast

Bronchus Stomach Duodenum Arm skin Cervical lymph node External iliac lymph node

Adult stage

Primary cutaneous diffuse large b-cell lymphoma, leg type Diffuse large b-cell lymphoma

10x gene expression flex

Cell

Homo sapiens

T cell Central nervous system macrophage Natural killer cell Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Amygdala excitatory neuron Committed oligodendrocyte precursor Lamp5 lhx6 neuron Eccentric medium spiny neuron Pvalb chandelier gabaergic interneuron Medial ganglionic eminence derived interneuron Microglial cell B cell Pericyte Cerebral cortex neuron Near-projecting glutamatergic cortical neuron Neuron Intratelencephalic-projecting glutamatergic cortical neuron Caudal ganglionic eminence derived interneuron Vascular associated smooth muscle cell Sst chodl gabaergic interneuron Astrocyte Fibroblast Medium spiny neuron

Agranular insular cortex

42-year-old stage 29-year-old stage 50-year-old stage

Normal

Male

10x 3' v3

Nucleus

Homo sapiens

Stromal cell Endothelial cell Lymphocyte Glial cell Pericyte Myofibroblast cell Fibroblast

Ascending colon Colonic epithelium Lamina propria of mucosa of colon Colon Mucosa of transverse colon Cecum mucosa Mucosa of sigmoid colon Descending colon Sigmoid colon

Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Adult stage Fourth decade stage Eighth decade stage

Normal Crohn disease

Female Male

10x 3' v1 10x 3' v3 10x 3' v2

Cell

Homo sapiens

T cell Blood vessel endothelial cell Retinal pigment epithelial cell Schwann cell Choroidal melanocyte Macrophage B cell Pericyte Fibroblast

Age-related macular degeneration Normal

10x multiome