Homo sapiens

Endothelial cell Mast cell Cardiac neuron Lymphocyte Adipocyte Mural cell Myeloid cell Cardiac muscle cell Fibroblast of cardiac tissue

Heart right ventricle Apex of heart Heart left ventricle Interventricular septum

Pediatric stage Sixth decade stage Fifth decade stage Third decade stage Seventh decade stage Postnatal stage Fourth decade stage Eighth decade stage

Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Normal Non-compaction cardiomyopathy

Female Male

10x 3' v2 10x 3' v3

Nucleus

Homo sapiens

Central memory cd4-positive, alpha-beta t cell T cell Effector memory cd4-positive, alpha-beta t cell Memory regulatory t cell Naive regulatory t cell Memory ccr4-positive regulatory t cell Cd4-positive, alpha-beta memory t cell Cd8-positive, alpha-beta regulatory t cell

Blood

66-year-old stage 69-year-old stage 75-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 61-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 44-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 80 year-old and over stage 49-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 83-year-old stage 40-year-old stage

Cytomegalovirus infection Normal

Female Male

10x gene expression flex

Cell

Homo sapiens

Natural killer cell Double negative t regulatory cell Gamma-delta t cell Enucleated reticulocyte Mast cell Cd8-positive, alpha-beta t cell Double-positive, alpha-beta thymocyte Classical monocyte Plasmablast Hematopoietic stem cell Cd4-positive, alpha-beta t cell B cell Mucosal invariant t cell Megakaryocyte-erythroid progenitor cell Blood cell Dendritic cell Non-classical monocyte

Blood

Sixth decade stage Fifth decade stage Seventh decade stage 90 year-old and over stage Fourth decade stage Eighth decade stage Ninth decade stage Young adult stage

Covid-19 Normal Influenza

Female Male

10x 5' v1

Cell

Homo sapiens

Blood vessel endothelial cell Endothelial cell of lymphatic vessel Conjunctival epithelial cell Endothelial cell Mast cell Schwann cell Melanocyte Leukocyte Smooth muscle cell Epithelial cell Lymphocyte Macrophage B cell Pericyte Progenitor cell Monocyte Fibroblast Myelinating schwann cell Keratocyte Corneal endothelial cell

Corneal epithelium Cornea Tunica fibrosa of eyeball Sclera Substantia propria of cornea Ocular surface region Corneal endothelium Corneo-scleral junction

69-year-old stage 75-year-old stage 19th week post-fertilization stage 13-year-old stage 21st week post-fertilization stage 34-year-old stage 65-year-old stage 23rd week post-fertilization stage 43-year-old stage 87-year-old stage 13th week post-fertilization stage 53-year-old stage 61-year-old stage 2-year-old stage 48-year-old stage 14th week post-fertilization stage 39-year-old stage 55-year-old stage 84-year-old stage 15th week post-fertilization stage 20th week post-fertilization stage 51-year-old stage 17th week post-fertilization stage 72-year-old stage 74-year-old stage 16-year-old stage 25-year-old stage 67-year-old stage 18th week post-fertilization stage 90 year-old and over stage 32-year-old stage 77-year-old stage 33-year-old stage 64-year-old stage Postnatal stage 22nd week post-fertilization stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 1-year-old stage 22-year-old stage Newborn stage (0-28 days) Eighth decade stage 83-year-old stage 11-year-old stage 27-year-old stage 10-year-old stage 11th week post-fertilization stage

Normal

Female Male

10x 3' v2 10x 3' v3 10x multiome

Nucleus Cell

Mus musculus

T cell Neutrophil Germinal center b cell Cycling t cell Cytotoxic t cell Mature nk t cell Centrocyte Group 2 innate lymphoid cell Natural t-regulatory cell Leukocyte Plasmacytoid dendritic cell Group 3 innate lymphoid cell Marginal zone b cell of lymph node T-helper 17 cell Macrophage Follicular b cell Cd103-positive dendritic cell Plasmablast Common myeloid progenitor Plasma cell Eosinophil Bm3 b cell Naive t cell Mucosal invariant t cell Lymphoid tissue–inducer cell Transitional stage b cell Naive b cell Basophil Conventional dendritic cell

Normal

10x 3' v3

Homo sapiens

Club cell Epithelial cell of stomach Stromal cell Ciliated cell Luminal cell of prostate epithelium Lung secretory cell Best4+ enterocyte Endothelial cell Kupffer cell Neuroendocrine cell Interstitial cell of cajal Epithelial cell of pancreas Hepatoblast Stem cell Basal cell Schwann cell Smooth muscle cell Paneth cell Epithelial cell Intestinal tuft cell Hepatic stellate cell Pancreatic a cell Enteroendocrine cell Mesodermal cell Goblet cell Thymocyte Pancreatic d cell Pulmonary alveolar type 1 cell Enterocyte Type b pancreatic cell Acinar cell Mesothelial cell Pancreatic epsilon cell Pericyte Neuron Colon epithelial cell Pancreatic ductal cell Hematopoietic cell Pulmonary alveolar type 2 cell M cell of gut

Bronchus Lung Stomach Corpus Biliary system Duodenum Pyloric antrum Intrahepatic bile duct Nasopharynx Ileum Liver Thyroid gland Colon Alveolar sac Intestine Pancreas Common bile duct Lung epithelium Gallbladder Prostate gland Salivary gland epithelium

Normal

10x 3' v2 10x 3' v3 10x 5' v1 10x multiome Cel-seq2 Sort-seq Seq-well s3 Smart-seq

Nucleus Cell

Homo sapiens

Blood vessel endothelial cell Natural killer cell Endothelial cell of lymphatic vessel Fibroblast of mammary gland Perivascular cell Mature nk t cell Mammary gland epithelial cell Cd4-positive helper t cell Luminal epithelial cell of mammary gland Leukocyte Cd8-positive, alpha-beta memory t cell Macrophage Unswitched memory b cell Tc1 cell Luminal adaptive secretory precursor cell of mammary gland Innate lymphoid cell Mural cell Basal-myoepithelial cell of mammary gland Plasma cell Luminal hormone-sensing cell of mammary gland Naive thymus-derived cd4-positive, alpha-beta t cell Naive b cell Dendritic cell Class switched memory b cell Effector memory cd8-positive, alpha-beta t cell

Breast

37-year-old stage 21-year-old stage 34-year-old stage 65-year-old stage 53-year-old stage 52-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 29-year-old stage 38-year-old stage 56-year-old stage 55-year-old stage 28-year-old stage 57-year-old stage 24-year-old stage 23-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 33-year-old stage 45-year-old stage 62-year-old stage 41-year-old stage 46-year-old stage 31-year-old stage 36-year-old stage 19-year-old stage 63-year-old stage 20-year-old stage 27-year-old stage 40-year-old stage

Normal

Female

10x 3' v3

Cell

Homo sapiens

Naive thymus-derived cd4-positive, alpha-beta t cell

Blood

66-year-old stage 69-year-old stage 75-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 61-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 44-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 80 year-old and over stage 49-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 83-year-old stage 40-year-old stage

Cytomegalovirus infection Normal

Female Male

10x gene expression flex

Cell

Mus musculus Homo sapiens

Cerebellar neuron Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Astrocyte of the cerebellum Cerebellar granule cell Cerebellar golgi cell Inhibitory interneuron Ependymal cell Macrophage Microglial cell Obsolete excitatory neuron Endothelial stalk cell Interneuron Bergmann glial cell Purkinje cell Fibroblast

Normal

10x 3' v3

Homo sapiens

T cell Natural killer cell Pro-b cell Erythroid lineage cell Plasmacytoid dendritic cell Promonocyte Hematopoietic stem cell Common myeloid progenitor Plasma cell B cell Granulocyte monocyte progenitor cell Megakaryocyte-erythroid progenitor cell Monocyte Conventional dendritic cell

Bone marrow

66-year-old stage 75-year-old stage 21-year-old stage 13-year-old stage 65-year-old stage 42-year-old stage 26-year-old stage 43-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 61-year-old stage 2-year-old stage 52-year-old stage 54-year-old stage 48-year-old stage 30-year-old stage 39-year-old stage 44-year-old stage 17-year-old stage 29-year-old stage 38-year-old stage 56-year-old stage 8-year-old stage 55-year-old stage 84-year-old stage 15-year-old stage 50-year-old stage 80-year-old stage 28-year-old stage 51-year-old stage 57-year-old stage 12-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 9-year-old stage 14-year-old stage 24-year-old stage 16-year-old stage 23-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage Adult stage 67-year-old stage 2-month-old stage 3-year-old stage 32-year-old stage 77-year-old stage 33-year-old stage 8-month-old stage 18-month-old stage 64-year-old stage 45-year-old stage 62-year-old stage 19-month-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 31-year-old stage 36-year-old stage 1-year-old stage 22-year-old stage 19-year-old stage 63-year-old stage 20-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 5-year-old stage 11-year-old stage 6-year-old stage 7-year-old stage 10-year-old stage 4-year-old stage

Myeloid leukemia Normal

Female Male

10x 3' v1 10x 3' v2 10x 3' v3 10x 5' v1 10x 5' v2 10x transcription profiling Sort-seq Seq-well Smart-seq2

Cell

Homo sapiens

Central memory cd4-positive, alpha-beta t cell T cell Effector memory cd4-positive, alpha-beta t cell Memory regulatory t cell Naive regulatory t cell Memory ccr4-positive regulatory t cell Cd4-positive, alpha-beta memory t cell Naive thymus-derived cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta regulatory t cell Double negative thymocyte

Blood

34-year-old stage 65-year-old stage 26-year-old stage 61-year-old stage 30-year-old stage 29-year-old stage 56-year-old stage 55-year-old stage 28-year-old stage 57-year-old stage 12-year-old stage 35-year-old stage 58-year-old stage 59-year-old stage 25-year-old stage 32-year-old stage 33-year-old stage 64-year-old stage 62-year-old stage 60-year-old stage 31-year-old stage 36-year-old stage 63-year-old stage 11-year-old stage 27-year-old stage

Cytomegalovirus infection Normal

Female Male

10x 3' v3

Cell

Homo sapiens

Mature gamma-delta t cell Cd8aa(i) thymocyte Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Mucosal invariant t cell Central memory cd8-positive, alpha-beta t cell Double negative thymocyte Effector memory cd8-positive, alpha-beta t cell

Blood

66-year-old stage 69-year-old stage 75-year-old stage 65-year-old stage 42-year-old stage 89-year-old stage 43-year-old stage 87-year-old stage 71-year-old stage 85-year-old stage 53-year-old stage 61-year-old stage 88-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 44-year-old stage 56-year-old stage 55-year-old stage 84-year-old stage 82-year-old stage 50-year-old stage 80-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 81-year-old stage 74-year-old stage 80 year-old and over stage 49-year-old stage 58-year-old stage 59-year-old stage 67-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 86-year-old stage 41-year-old stage 70-year-old stage 46-year-old stage 60-year-old stage 78-year-old stage 63-year-old stage 47-year-old stage 76-year-old stage 79-year-old stage 73-year-old stage 83-year-old stage 40-year-old stage

Cytomegalovirus infection Normal

Female Male

10x gene expression flex

Cell