Homo sapiens

Natural killer cell Cd8-positive, alpha-beta t cell Follicular dendritic cell Endothelial cell of lymphatic vessel Regulatory t cell Fibroblast Monocyte Pericyte Monocyte-derived dendritic cell Macrophage Dendritic cell Adipocyte Conventional dendritic cell Plasmacytoid dendritic cell Endothelial cell Cd4-positive, alpha-beta t cell T follicular helper cell Smooth muscle cell

Lymph node

Tenth decade stage Fifth decade stage Ninth decade stage Eighth decade stage Fourth decade stage Seventh decade stage Sixth decade stage Third decade stage

Normal B-cell non-hodgkin lymphoma

Female Male

10x multiome

Nucleus

Macaca fascicularis Mus musculus

Oligodendrocyte Unipolar brush cell Interneuron Fibroblast Cerebellar golgi cell Endothelial stalk cell Connective tissue cell Purkinje cell Central nervous system macrophage Ependymal cell Oligodendrocyte precursor cell Cerebellar granule cell Microglial cell Neuron Brain pericyte Bergmann glial cell Cell Astrocyte

Normal

10x 3' v3

Mus musculus musculus

Oligodendrocyte Fibroblast Mural cell Oligodendrocyte precursor cell Microglial cell Brain microvascular endothelial cell Neuron Choroid plexus epithelial cell Astrocyte

Normal

10x 3' transcription profiling

Homo sapiens

Endocardial cell Endothelial cell of lymphatic vessel Mast cell Vascular associated smooth muscle cell Cardiac neuron Pericyte Macrophage Mesothelial cell Cardiac ventricle fibroblast Adipocyte Lymphocyte Cardiac muscle cell Cardiac endothelial cell

Normal Dilated cardiomyopathy Hypertrophic cardiomyopathy

10x 3' v3

Homo sapiens

Mature nk t cell Non-classical monocyte Natural killer cell Activated cd8-positive, alpha-beta t cell Erythrocyte Neutrophil Classical monocyte Cd8-positive, alpha-beta t cell Regulatory t cell Mast cell Cd4-positive, alpha-beta thymocyte Leukocyte Erythroid progenitor cell Monocyte Cd8-positive, alpha-beta thymocyte Common myeloid progenitor Hematopoietic cell Myeloid leukocyte Basophil Naive thymus-derived cd8-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Naive thymus-derived cd4-positive, alpha-beta t cell Macrophage Gamma-delta t cell T cell Hematopoietic precursor cell Mononuclear phagocyte Myeloid cell Granulocyte Erythroid lineage cell Langerhans cell Platelet Plasma cell Microglial cell Tissue-resident macrophage Plasmacytoid dendritic cell Myeloid dendritic cell Innate lymphoid cell Cd4-positive, alpha-beta t cell T follicular helper cell Intermediate monocyte B cell Hematopoietic stem cell Colon macrophage Thymocyte

Abdominal aorta Adipose tissue Anterior part of tongue Anterior segment of eyeball Aorta Ascending colon Bladder organ Blood Bone marrow Brown adipose tissue Buccal mucosa Cardiac atrium Cardiac ventricle Chorioretinal region Conjunctiva Cornea Coronary artery Cortex of kidney Crista ampullaris Duodenum Endocrine pancreas Endometrium Exocrine pancreas Eye Eyelid Heart Heart right ventricle Ileum Inferior vena cava Inguinal lymph node Jejunum Kidney Lacrimal gland Large intestine Left coronary artery Left ovary Liver Lung Lymph node Mammary gland Mesenteric lymph node Mucosa of stomach Muscle of abdomen Muscle of pelvic diaphragm Muscularis mucosae of stomach Myometrium Ocular surface region Ovary Parotid gland Posterior part of tongue Posterior segment of eyeball Prostate gland Retinal neural layer Right cardiac atrium Right ovary Sclera Sigmoid colon Skin of abdomen Skin of body Skin of chest Small intestine Spleen Stomach Stomach smooth muscle Subcutaneous adipose tissue Sublingual gland Submandibular gland Testis Thoracic aorta Thymus Trachea Uterus Utricle of membranous labyrinth Vasculature

26-year-old stage 37-year-old stage 22-year-old stage 42-year-old stage 59-year-old stage 61-year-old stage 57-year-old stage 74-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 36-year-old stage 45-year-old stage 69-year-old stage 67-year-old stage 40-year-old stage 60-year-old stage 38-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v3 Smart-seq3 10x 5' v2 Smart-seq2

Cell

Homo sapiens

Megakaryocyte Natural killer cell Erythrocyte Neutrophil Late pro-b cell Regulatory t cell Granulocyte monocyte progenitor cell Fraction a pre-pro b cell Mast cell Vascular associated smooth muscle cell Fibroblast Promonocyte Monocyte Common myeloid progenitor Megakaryocyte-erythroid progenitor cell Group 3 innate lymphoid cell Naive thymus-derived cd8-positive, alpha-beta t cell Group 2 innate lymphoid cell Double negative thymocyte Naive thymus-derived cd4-positive, alpha-beta t cell Macrophage B-2 b cell Dendritic cell Hematopoietic multipotent progenitor cell T cell Mature b cell Large pre-b-ii cell Common dendritic progenitor Small pre-b-ii cell Granulocyte Promyelocyte Osteoclast Pro-b cell Langerhans cell Kupffer cell Plasma cell B-1 b cell Double-positive, alpha-beta thymocyte Plasmacytoid dendritic cell Early lymphoid progenitor Innate lymphoid cell Myelocyte Pre-conventional dendritic cell Immature b cell Hematopoietic stem cell Cd8-alpha-alpha-positive, alpha-beta intraepithelial t cell

Bone marrow Gut wall Kidney Liver Mesenteric lymph node Skin of body Spleen Thymus Yolk sac

15th week post-fertilization stage 11th week post-fertilization stage 14th week post-fertilization stage 9th week post-fertilization stage 13th week post-fertilization stage Carnegie stage 23 Carnegie stage 22 12th week post-fertilization stage 10th week post-fertilization stage 17th week post-fertilization stage 16th week post-fertilization stage Carnegie stage 19 Carnegie stage 20 Carnegie stage 13

Normal

Female Male

10x 3' v2 10x 5' v1

Cell

Homo sapiens

Pulmonary artery endothelial cell Non-classical monocyte Natural killer cell Nasal mucosa goblet cell Respiratory tract hillock cell Alveolar type 1 fibroblast cell Classical monocyte Cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Pulmonary alveolar type 1 cell Tracheobronchial goblet cell Bronchial goblet cell Capillary endothelial cell Mast cell Cd1c-positive myeloid dendritic cell Fibroblast Club cell Alveolar adventitial fibroblast Elicited macrophage Epithelial cell of lower respiratory tract Tracheobronchial smooth muscle cell Respiratory basal cell Multiciliated columnar cell of tracheobronchial tree Dendritic cell T cell Mesothelial cell Tracheobronchial serous cell Multiciliated epithelial cell Bronchus fibroblast of lung Vein endothelial cell Pulmonary alveolar epithelial cell Brush cell of tracheobronchial tree Acinar cell Conventional dendritic cell Lung macrophage Pulmonary alveolar type 2 cell Plasma cell Lung pericyte Stromal cell Ionocyte Alveolar macrophage Myofibroblast cell Pulmonary neuroendocrine cell Plasmacytoid dendritic cell Serous secreting cell Cd4-positive, alpha-beta t cell Smooth muscle cell B cell Mucus secreting cell Hematopoietic stem cell

Lung parenchyma Nose Respiratory airway

64-year-old stage 26-year-old stage 52-year-old stage 68-year-old stage 41-year-old stage 35-year-old stage Fifth decade stage 63-year-old stage 15-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 24-year-old stage 22-year-old stage 75-year-old stage 34-year-old stage 31-year-old stage 42-year-old stage 49-year-old stage 59-year-old stage 54-year-old stage 25-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 21-year-old stage 53-year-old stage Fourth decade stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage Seventh decade stage 47-year-old stage 36-year-old stage 76-year-old stage 69-year-old stage 40-year-old stage 62-year-old stage Sixth decade stage 10-year-old stage 18-year-old stage 38-year-old stage 23-year-old stage 30-year-old stage 27-year-old stage 51-year-old stage 71-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3 10x 5' v2 10x 3' v1 10x 5' v1

Cell

Homo sapiens

Endothelial cell of lymphatic vessel Pulmonary alveolar type 1 cell Capillary endothelial cell Mast cell Fibroblast Monocyte Tracheobronchial smooth muscle cell Nkp46-positive innate lymphoid cell, human Macrophage Dendritic cell T cell Multiciliated epithelial cell Vein endothelial cell Pulmonary alveolar type 2 cell Circulating fibrocyte Myofibroblast cell Secretory cell Endothelial cell of artery B cell Basal cell Lung secretory cell

Lung parenchyma Nose Respiratory airway

64-year-old stage 26-year-old stage 50-year-old stage 52-year-old stage 68-year-old stage 41-year-old stage 35-year-old stage 63-year-old stage 15-year-old stage 37-year-old stage 29-year-old stage 58-year-old stage 24-year-old stage 22-year-old stage 75-year-old stage 34-year-old stage 31-year-old stage 42-year-old stage 49-year-old stage 59-year-old stage 54-year-old stage 25-year-old stage 66-year-old stage 61-year-old stage 57-year-old stage 21-year-old stage 53-year-old stage 46-year-old stage 56-year-old stage 55-year-old stage 44-year-old stage 47-year-old stage 36-year-old stage 32-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 40-year-old stage 62-year-old stage 10-year-old stage 18-year-old stage 38-year-old stage 23-year-old stage 30-year-old stage 27-year-old stage 71-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3 10x 5' v2 10x 3' v1 10x 5' v1

Cell

Homo sapiens

Schwann cell Keratocyte Endothelial cell of lymphatic vessel Capillary endothelial cell Mast cell Fibroblast Corneal endothelial cell Monocyte Pericyte Myelinating schwann cell Macrophage Endothelial cell of venule Epithelial cell Lymphocyte Conjunctival epithelial cell Smooth muscle cell Endothelial cell of artery B cell Melanocyte

Cornea Corneal endothelium Corneal epithelium Corneo-scleral junction Ocular surface region Sclera Substantia propria of cornea Tunica fibrosa of eyeball

64-year-old stage 65-year-old stage 43-year-old stage 41-year-old stage 90 year-old and over stage 22-year-old stage 75-year-old stage 84-year-old stage 34-year-old stage 86-year-old stage 25-year-old stage 61-year-old stage 11-year-old stage 2-year-old stage 74-year-old stage Eighth decade stage 1-year-old stage 83-year-old stage 53-year-old stage 55-year-old stage 77-year-old stage 32-year-old stage 45-year-old stage 70-year-old stage 69-year-old stage 67-year-old stage Newborn stage (0-28 days) Postnatal stage 13-year-old stage 87-year-old stage 62-year-old stage 16-year-old stage 10-year-old stage 39-year-old stage 72-year-old stage 27-year-old stage 48-year-old stage 51-year-old stage 33-year-old stage

Normal

Female Male

10x 3' v2 10x 3' v3

Cell

Homo sapiens

Gabaergic amacrine cell Amacrine cell Starburst amacrine cell Glycinergic amacrine cell

Fovea centralis Macula lutea Macula lutea proper Peripheral region of retina

80 year-old and over stage 85-year-old stage 80-year-old stage 64-year-old stage 50-year-old stage 52-year-old stage 65-year-old stage 68-year-old stage 82-year-old stage 43-year-old stage 41-year-old stage 63-year-old stage 90 year-old and over stage 15-year-old stage 58-year-old stage 24-year-old stage 73-year-old stage Late adult stage 75-year-old stage 3-year-old stage 84-year-old stage 34-year-old stage 86-year-old stage 25-year-old stage 66-year-old stage 11-year-old stage 74-year-old stage Eighth decade stage 21-year-old stage 83-year-old stage 53-year-old stage 46-year-old stage 77-year-old stage 78-year-old stage 47-year-old stage 32-year-old stage 60-79 year-old stage 70-year-old stage 81-year-old stage 76-year-old stage 69-year-old stage 67-year-old stage 88-year-old stage 60-year-old stage 62-year-old stage 16-year-old stage 10-year-old stage 18-year-old stage Prime adult stage 30-year-old stage 72-year-old stage 27-year-old stage 17-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Gabaergic amacrine cell Amacrine cell Starburst amacrine cell Glycinergic amacrine cell

Normal

10x 3' v3

Drosophila melanogaster

Adult renal stem cell Adult brain cell body glial cell Proximal medullary amacrine neuron pm4 Dopaminergic neuron Hemocyte Adult malpighian tubule stellate cell of main segment Columnar neuron t1 Enteroblast Transmedullary y neuron tmy14 Transmedullary neuron tm2 Lamina monopolar neuron l5 Adult neuron Transmedullary neuron tm20 Alpha/beta kenyon cell Distal medullary amacrine neuron dm11 Transmedullary y neuron tmy4 Adult alary muscle cell Lamina monopolar neuron l2 Distal medullary amacrine neuron dm10 Transmedullary neuron tm5c Tendon cell Outer photoreceptor cell Adult malpighian tubule bar-shaped cell of initial segment Gustatory receptor neuron Enteroendocrine cell Ensheathing glial cell Gamma kenyon cell Medulla intrinsic neuron mi9 Johnston organ neuron Adult glial cell Adult olfactory receptor neuron or13a Ovarian sheath muscle cell Spermatid Male accessory gland secondary cell Polar follicle cell Adult olfactory receptor neuron gr21a/63a Early elongation stage spermatid Transmedullary neuron tm9 Labral sense organ mechanosensory neuron T3 neuron Adult brain perineurial glial cell Germline cell Adult midgut enterocyte Nociceptive neuron Transmedullary y neuron tmy8 Follicle cell Leg taste bristle chemosensory neuron Medulla intrinsic neuron mi1 Adult olfactory receptor neuron or65 Lamina monopolar neuron l1 Enterocyte of posterior adult midgut epithelium Photoreceptor cell r7 Adult malpighian tubule principal cell of lower ureter Lobula columnar neuron lc17 Lobula columnar neuron lc10 Dorsal appendage forming follicle cell Early-mid elongation-stage spermatid Epithelial cell T2 neuron Stretch follicle cell Optic-lobe-associated cortex glial cell Adult malpighian tubule principal cell of initial segment Multidendritic neuron Lamina wide-field 2 neuron Transmedullary neuron tm1 Adult enterocyte Distal medullary amacrine neuron dm12 Medulla intrinsic neuron mi15 Lamina monopolar neuron l3 Chordotonal neuron Olfactory receptor neuron Visceral muscle cell Transmedullary neuron tm4 Proximal medullary amacrine neuron pm2 Adult oenocyte Antennal lobe projection neuron Mechanosensory neuron of leg chordotonal organ Escort cell Eye photoreceptor cell Adult malpighian tubule principal cell Adult differentiating enterocyte Distal medullary amacrine neuron dm8a Distal medullary amacrine neuron dm3 Mid-late elongation-stage spermatid Gustatory receptor neuron of the labellum Pigment cell Adult optic chiasma glial cell Leg muscle motor neuron Alpha'/beta' kenyon cell Cardial cell Intestinal stem cell Midgut large flat cell Auditory sensory neuron Maxillary palp olfactory receptor neuron Cell body glial cell Adult olfactory receptor neuron or88a Stalk follicle cell Cns surface glial cell Subperineurial glial cell Male accessory gland main cell Indirect flight muscle cell Embryonic/larval crystal cell Transmedullary y neuron tmy5a Kenyon cell Distal medullary amacrine neuron dm9 Centrifugal neuron c3 Adult malpighian tubule principal cell of lower segment Muscle cell Adult olfactory receptor neuron or92a Transmedullary neuron tm3 Adult olfactory receptor neuron ir75d Adult abdominal pericardial cell Centrifugal neuron c2 Sensory neuron Spermatocyte Lamina wide-field 1 neuron Adult astrocyte-like glial cell Eo sensory organ accessory cell Ocellar retinula cell Medulla intrinsic neuron mi4 Adult olfactory receptor neuron or67d Lobula columnar neuron lc12 Adult olfactory receptor neuron or47b Lamina monopolar neuron l4 Adult lobula astrocyte-like glial cell Cone cell Adult dopaminergic pam neuron Mechanosensory neuron Enterocyte of anterior adult midgut epithelium Adult heart ventral longitudinal muscle cell Adult somatic muscle cell of head Tormogen cell Copper cell Spermatogonium Photoreceptor cell r8 T2a neuron

Antenna Heart Oenocyte Gut Malpighian tubule Proboscis Maxillary palp Haltere Head Leg Ovary Testis Trachea Wing Fat body Body wall Male reproductive gland

Day 2 of adulthood Day 5 of adulthood Day 3 of adulthood Day 1 of adulthood

Normal

Female Male Mixed sex

10x 3' v3