Homo sapiens

T cell Effector cd8-positive, alpha-beta t cell Erythrocyte Follicular dendritic cell Mature nk t cell Cd8-positive, alpha-beta t cell Exhausted t cell Plasmacytoid dendritic cell Cd4-positive, alpha-beta cytotoxic t cell Naive thymus-derived cd8-positive, alpha-beta t cell Regulatory t cell Myeloid cell Plasma cell Cd4-positive, alpha-beta t cell Malignant cell T follicular helper cell B cell Naive thymus-derived cd4-positive, alpha-beta t cell

Lymph node

Follicular lymphoma Normal

10x 5' v1

Cell

Macaca mulatta

Astrocyte

Dorsolateral prefrontal cortex Brodmann (1909) area 19 Medial dorsal nucleus of thalamus Primary visual cortex Ventral lateral nucleus of thalamus Inferior temporal gyrus Medulla oblongata Prefrontal cortex Midbrain Entorhinal cortex Nucleus accumbens Cerebrocerebellum Primary somatosensory cortex Primary auditory cortex Primary motor cortex Inferior parietal cortex Head of caudate nucleus Corpus callosum Hippocampal formation Perirhinal cortex Pons Cerebellar vermis Anterior cingulate cortex Superior temporal sulcus Superior parietal cortex Lateral geniculate body Amygdala

Juvenile stage Prime adult stage

Normal

Female Male

Sci-rna-seq3

Nucleus

Homo sapiens

Osteoblast Muscle cell Natural killer cell Endothelial cell of lymphatic vessel Erythrocyte Endothelial cell Fibroblast of dermis Mast cell Peridermal cell Hypertrophic chondrocyte Tendon cell Basal cell Endothelial cell of artery Schwann cell Melanocyte Smooth muscle cell Articular chondrocyte Connective tissue cell Early lymphoid progenitor Primitive red blood cell Chondroblast Macrophage Myelocyte Common myeloid progenitor Vein endothelial cell Mesenchymal cell Megakaryocyte Skeletal muscle myoblast Myoblast B cell Pericyte Neuron Reticulocyte Monocyte Conventional dendritic cell Fibroblast Schwann cell precursor Chondrocyte Muscle fibroblast

Hindlimb Forelimb

Carnegie stage 19 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage Carnegie stage 17 Carnegie stage 16 Carnegie stage 15 Carnegie stage 18

Normal

Female Male

10x 5' v1 10x 3' v2

Cell

Homo sapiens

Oligodendrocyte precursor cell Endothelial cell Oligodendrocyte Lymphocyte Macrophage Microglial cell Neoplastic cell B cell Pericyte Monocyte Vascular associated smooth muscle cell Astrocyte Fibroblast

Right temporal lobe

73-year-old stage

Glioblastoma

Male

10x 3' v3

Cell

Homo sapiens

Oligodendrocyte precursor cell Oligodendrocyte Vascular leptomeningeal cell Pvalb chandelier gabaergic interneuron Lamp5 gabaergic interneuron Microglial cell Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron L5 extratelencephalic projecting glutamatergic cortical neuron L6b glutamatergic cortical neuron Pvalb gabaergic interneuron Near-projecting glutamatergic cortical neuron Cerebral cortex endothelial cell Caudal ganglionic eminence derived interneuron Sncg gabaergic interneuron Astrocyte of the cerebral cortex Sst gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron

Anterior cingulate cortex

42-year-old stage 43-year-old stage 29-year-old stage 50-year-old stage 60-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Hepatocyte Natural killer cell Pro-t cell Neutrophilic myeloblast Endothelial cell Kupffer cell Pro-b cell Mast cell Multi fate stem cell Stem cell Erythroid lineage cell Plasmacytoid dendritic cell Precursor b cell Common dendritic progenitor Macrophage Innate lymphoid cell Common myeloid progenitor Hematopoietic multipotent progenitor cell Megakaryocyte B cell Granulocyte monocyte progenitor cell Common lymphoid progenitor Megakaryocyte-erythroid progenitor cell Fraction a pre-pro b cell Monocyte Conventional dendritic cell Fibroblast Mononuclear phagocyte

Yolk sac Liver Metanephros Zone of skin

Carnegie stage 14 13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 17th week post-fertilization stage 12th week post-fertilization stage 9th week post-fertilization stage Carnegie stage 23 10th week post-fertilization stage 18th week post-fertilization stage Carnegie stage 22 11th week post-fertilization stage

Normal

Male Female

10x genomics v2

Homo sapiens

Cycling t cell Natural killer cell Mast cell Cd8-positive, alpha-beta t cell Plasmacytoid dendritic cell, human Macrophage Cd4-positive, cd25-positive, alpha-beta regulatory t cell Myeloid cell Plasma cell T follicular helper cell B cell Naive thymus-derived cd4-positive, alpha-beta t cell Monocyte Conventional dendritic cell

Gingiva of lower jaw Hypopharynx Buccal mucosa Alveolar ridge of mandible Larynx Mandible Tongue Oropharynx Oral cavity Mouth floor

66-year-old stage 69-year-old stage 75-year-old stage 65-year-old stage 43-year-old stage 53-year-old stage 61-year-old stage 54-year-old stage 48-year-old stage 56-year-old stage 55-year-old stage 50-year-old stage 80-year-old stage 51-year-old stage 57-year-old stage 72-year-old stage 74-year-old stage 35-year-old stage 58-year-old stage 67-year-old stage 32-year-old stage 77-year-old stage 64-year-old stage 45-year-old stage 62-year-old stage 70-year-old stage 60-year-old stage 18-year-old stage 73-year-old stage

Head and neck squamous cell carcinoma

Female Male

10x 5' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Neutrophil Club cell Stromal cell Natural killer cell Erythrocyte Pulmonary capillary endothelial cell Gamma-delta t cell Mature nk t cell Mast cell Cd8-positive, alpha-beta t cell Platelet Basal cell Lung goblet cell Leukocyte Classical monocyte Smooth muscle cell Lung multiciliated epithelial cell Lung macrophage Regulatory t cell Lung endothelial cell Fibroblast of lung Plasma cell Cd4-positive, alpha-beta t cell Mesothelial cell B cell Pulmonary alveolar type 2 cell Lung pericyte Non-classical monocyte

Upper lobe of left lung

36-year-old stage

Covid-19

Male

10x 3' v3

Cell

Homo sapiens

Supporting cell Erythrocyte Endothelial cell Sertoli cell Epithelial cell Neural cell Mural cell Mesenchymal cell Mesothelial cell Germ cell Leydig cell Hematopoietic cell

Gonad

Carnegie stage 19 19th week post-fertilization stage 21st week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 17th week post-fertilization stage 12th week post-fertilization stage 16th week post-fertilization stage 9th week post-fertilization stage Carnegie stage 17 11th week post-fertilization stage

Normal

Male

10x 5' v2 10x 5' v1

Cell

Homo sapiens

Effector cd8-positive, alpha-beta t cell Activated cd4-positive, alpha-beta t cell Cd8-positive, alpha-beta t cell Exhausted t cell Naive thymus-derived cd8-positive, alpha-beta t cell T-helper 17 cell Regulatory t cell Myeloid cell Cd4-positive, alpha-beta t cell Cd4-positive, alpha-beta memory t cell, cd45ro-positive Effector memory cd8-positive, alpha-beta t cell

T cell

66-year-old stage 42-year-old stage 61-year-old stage 52-year-old stage 54-year-old stage 68-year-old stage 48-year-old stage 44-year-old stage 38-year-old stage 28-year-old stage 57-year-old stage 74-year-old stage 24-year-old stage 58-year-old stage 59-year-old stage 64-year-old stage 70-year-old stage 60-year-old stage 63-year-old stage

B-cell non-hodgkin lymphoma

Female Male

10x 5' v1

Cell

Homo sapiens

Glioblast

Striatum Medulla oblongata Hindbrain Telencephalon Cortex Midbrain Dorsal plus ventral thalamus Lower layers of the cortex Frontal cortex Entorhinal cortex Midbrain tectum Metencephalon Basal forebrain Cerebellum Brain Hypothalamus Cerebellar peduncular complex Upper layers of the cortex Caudate-putamen Hippocampal formation Diencephalon Pons Cerebral subcortex Occipital cortex Forebrain

13th week post-fertilization stage 14th week post-fertilization stage 15th week post-fertilization stage 12th week post-fertilization stage Carnegie stage 20 9th week post-fertilization stage 10th week post-fertilization stage Carnegie stage 22 Carnegie stage 16 Carnegie stage 15 Carnegie stage 18 11th week post-fertilization stage

Normal

10x 3' v3 10x 3' v2

Cell

Mus musculus Heterocephalus glaber

T cell Splenic red pulp macrophage Neutrophil Granulocyte Natural killer cell Erythrocyte Mast cell Cd8-positive, alpha-beta t cell Erythroid lineage cell Plasmacytoid dendritic cell Cd8-positive, alpha-beta memory t cell Naive thymus-derived cd8-positive, alpha-beta t cell Obsolete animal cell Splenic macrophage Memory b cell Plasma cell Type i nk t cell Cd4-positive, alpha-beta memory t cell B cell Cd8-alpha-positive cd11b-negative dendritic cell Naive t cell Naive thymus-derived cd4-positive, alpha-beta t cell Monocyte Blood cell Marginal zone b cell of spleen Dendritic cell

Spleen Blood

Post-juvenile adult stage 2-month-old stage

Normal

Male Female

10x genomics v2 Illumina