Homo sapiens

Pancreatic a cell

Islet of langerhans

54-year-old stage 35-year-old stage 62-year-old stage 26-year-old stage 53-year-old stage 21-year-old stage 61-year-old stage 57-year-old stage 49-year-old stage 42-year-old stage 52-year-old stage 48-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 59-year-old stage 30-year-old stage 55-year-old stage 58-year-old stage 50-year-old stage 51-year-old stage 66-year-old stage 32-year-old stage 63-year-old stage 60-year-old stage 25-year-old stage 37-year-old stage 34-year-old stage

Type 2 diabetes mellitus Prediabetes syndrome Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Type ii muscle cell Type i muscle cell Muscle cell

Intercostal muscle

Third decade stage Sixth decade stage Fourth decade stage Eighth decade stage Young adult stage Seventh decade stage

Normal

Female Male

10x 3' v3 10x 3' v2

Nucleus

Callithrix jacchus

Neuron

Lateral nuclear group of thalamus Medial dorsal nucleus of thalamus Lateral geniculate body Ventral lateral nucleus of thalamus Ventral thalamus Dorsal thalamus Thalamic complex

Prime adult stage Late adult stage

Normal

Female Male

10x 3' v3

Nucleus

Mus musculus

Cortical interneuron L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex L6b glutamatergic cortical neuron Astrocyte Lamp5 gabaergic interneuron Sst chodl gabaergic interneuron Corticothalamic-projecting glutamatergic cortical neuron Vip gabaergic interneuron L2/3-6 intratelencephalic projecting glutamatergic neuron Oligodendrocyte Pyramidal neuron L6 corticothalamic-projecting glutamatergic cortical neuron Pericyte Hippocampal neuron L5/6 near-projecting glutamatergic neuron of the primary motor cortex Pvalb gabaergic interneuron Meis2 expressing cortical gabaergic cell L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Glutamatergic neuron Cajal-retzius cell Sncg gabaergic interneuron Central nervous system macrophage Sst gabaergic interneuron L5 extratelencephalic projecting glutamatergic cortical neuron L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex Endothelial cell Vascular leptomeningeal cell (mmus)

Primary motor cortex Medial orbital frontal cortex Primary visual cortex Primary somatosensory cortex Posterior parietal association areas Retrosplenial region Temporal cortex Lateral entorhinal cortex Auditory cortex Agranular insular cortex Gustatory cortex Hippocampal formation Anterior cingulate cortex Medial entorhinal cortex Prefrontal cortex Secondary somatosensory cortex Visual cortex Subicular complex Frontal cortex Claustrum of brain

14-week-old stage 12-week-old stage 11-week-old stage 8-week-old stage 7-week-old stage 9-week-old stage 13-week-old stage 10-week-old stage 15-week-old stage

Normal

Female Male

Smart-seq v4

Cell

Homo sapiens

Periportal region hepatocyte Kupffer cell Inflammatory macrophage Cholangiocyte B cell Midzonal region hepatocyte Blood vessel endothelial cell Centrilobular region hepatocyte Erythroid lineage cell Natural killer cell Hepatic stellate cell Endothelial cell of pericentral hepatic sinusoid

Caudate lobe of liver

Young adult stage Prime adult stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell Nucleus

Homo sapiens

Endothelial cell of vascular tree Endothelial cell of arteriole Cardiac endothelial cell Vein endothelial cell Colon endothelial cell Capillary endothelial cell Endothelial cell of venule Endothelial cell of lymphatic vessel Retinal blood vessel endothelial cell Endothelial cell Endothelial cell of artery

Vasculature Skin of body Trachea Cardiac ventricle Chorioretinal region Myometrium Brown adipose tissue Left coronary artery Lacrimal gland Stomach Ascending colon Endometrium Sigmoid colon Lung Crista ampullaris Bladder organ Aorta Subcutaneous adipose tissue Mesenteric lymph node Liver Mucosa of stomach Conjunctiva Exocrine pancreas Ileum Stomach smooth muscle Right cardiac atrium Muscle of abdomen Cornea Inferior vena cava Right ovary Prostate gland Skin of chest Abdominal aorta Large intestine Bone marrow Sclera Cardiac atrium Posterior part of tongue Kidney Sublingual gland Adipose tissue Eyelid Ovary Spleen Anterior part of tongue Thoracic aorta Uterus Muscle of pelvic diaphragm Small intestine Thymus Left ovary Buccal mucosa Posterior segment of eyeball Heart Skin of abdomen Jejunum Heart right ventricle Anterior segment of eyeball Coronary artery Duodenum Parotid gland Mammary gland Submandibular gland Testis Inguinal lymph node Lymph node Endocrine pancreas Eye Utricle of membranous labyrinth

74-year-old stage 26-year-old stage 61-year-old stage 57-year-old stage 36-year-old stage 40-year-old stage 38-year-old stage 45-year-old stage 59-year-old stage 55-year-old stage 33-year-old stage 69-year-old stage 60-year-old stage 56-year-old stage 37-year-old stage 46-year-old stage 67-year-old stage

Normal

Female Male

10x 3' v3 Smart-seq3 10x 5' v2 Smart-seq2

Cell

Homo sapiens

Myeloid cell Mast cell Plasma cell B cell Natural killer cell T cell

Adrenal gland Lung Pleural effusion Liver Brain Bone spine Axilla Lymph node

62-year-old stage 78-year-old stage 73-year-old stage 74-year-old stage 72-year-old stage 85-year-old stage 81-year-old stage 57-year-old stage 82-year-old stage 70-year-old stage 55-year-old stage 75-year-old stage 79-year-old stage 64-year-old stage 68-year-old stage 77-year-old stage 69-year-old stage 76-year-old stage 80-year-old stage 84-year-old stage 67-year-old stage 65-year-old stage 71-year-old stage 44-year-old stage 47-year-old stage

Normal Lung adenocarcinoma Small cell lung carcinoma

Female Male

10x 3' transcription profiling 10x 3' v3 10x 3' v2

Cell

Homo sapiens

Offx cell Invaginating midget bipolar cell Retinal bipolar neuron Diffuse bipolar 3b cell Diffuse bipolar 4 cell Diffuse bipolar 3a cell Diffuse bipolar 6 cell Giant bipolar cell On-blue cone bipolar cell Rod bipolar cell Flat midget bipolar cell Diffuse bipolar 1 cell Diffuse bipolar 2 cell

Chorioretinal region Peripheral region of retina Fovea centralis Retinal neural layer Macula lutea proper

54-year-old stage Adult stage 78-year-old stage 74-year-old stage 53-year-old stage 82-year-old stage 42-year-old stage 86-year-old stage 89-year-old stage 64-year-old stage 68-year-old stage 69-year-old stage 60-year-old stage 80-year-old stage 65-year-old stage 71-year-old stage

Normal

Female Male

10x 3' v3 10x 3' v2

Cell

Homo sapiens

Dendritic cell, human Stromal cell B cell Cd8-positive, alpha-beta t cell Natural killer cell Macrophage Monocyte Cd4-positive, alpha-beta t cell

Cerebrospinal fluid

54-year-old stage 73-year-old stage 61-year-old stage 70-year-old stage 40-year-old stage 45-year-old stage 55-year-old stage 58-year-old stage 69-year-old stage 63-year-old stage 60-year-old stage 56-year-old stage 67-year-old stage 71-year-old stage 34-year-old stage

Brain cancer Lymphoma Glioblastoma Inflammatory disease

Female Male

10x 5' v2

Cell

Homo sapiens

Enteroendocrine cell Transit amplifying cell Enterocyte Tuft cell of small intestine Paneth cell Intestine goblet cell Mucous neck cell of gastric gland Foveolar cell of stomach Best4+ enterocyte Intestinal crypt stem cell M cell of gut

Ileum lamina propria Ileal epithelium Mesenteric lymph node Ileum Small intestine Duodenal epithelium Jejunum Duodenum Epithelium of small intestine Lamina propria of small intestine

9-year-old stage Third decade stage 13-year-old stage Sixth decade stage 4-year-old stage 52-year-old stage 6-year-old stage 12-year-old stage 45-year-old stage Eighth decade stage 10-year-old stage 14-year-old stage 50-year-old stage 11-year-old stage Fifth decade stage 31-year-old stage 87-year-old stage 60-year-old stage Prime adult stage 67-year-old stage Seventh decade stage

Crohn disease Normal

Female Male

10x 5' transcription profiling 10x 3' v1 10x 5' v2 10x 5' v1 10x 3' v2

Cell

Homo sapiens

Fibro/adipogenic progenitor cell Schwann cell Myeloid cell Mast cell Smooth muscle cell Hematopoietic cell Pericyte Lymphocyte Adipocyte Endothelial cell of lymphatic vessel Macrophage Neuron associated cell Mesothelial cell Endothelial cell

Subcutaneous abdominal adipose tissue Visceral abdominal adipose tissue

54-year-old stage 35-year-old stage 62-year-old stage 27-year-old stage 26-year-old stage 53-year-old stage 21-year-old stage 41-year-old stage 18-year-old stage 51-year-old stage 66-year-old stage 28-year-old stage 37-year-old stage 47-year-old stage

Normal

Female Male

10x 3' v3

Nucleus

Homo sapiens

Endothelial cell of vascular tree Keratinocyte Neural progenitor cell Mesenchymal stem cell Epithelial cell Cd141-positive myeloid dendritic cell Malignant cell B cell Gamma-delta t cell Regulatory t cell Pericyte Myofibroblast cell Plasmacytoid dendritic cell Cd8-positive, alpha-beta t cell Endothelial cell of lymphatic vessel Granulocyte monocyte progenitor cell Natural killer cell Macrophage Mesenchymal stem cell of adipose tissue Basal cell Naive b cell Endothelial cell

Cervical cancer

10x 3' v3